Protein Alignment CG2111 and CG5849

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Alignment Length: 946
• Identity: 229/946 - (24%)
• Similarity: 388/946 - (41%)
• Gaps: 156/946 - (16%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNG 89
            |||....||.|::.|.:.|::....|.|...||:...:||..|||:|               ||.
  Fly    30 RLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHA---------------KNL 79

  Fly    90 NSVPVSSIQMDIKLSRLTVSLKRPLKVNVT------------------YSMRVAFTSVLRNDNTG 136
            ..:.::..::..:.|.:...|...|.....                  |.:.:.:|:::.:...|
  Fly    80 TDIQITVHRLMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASRPAG 144

  Fly   137 FYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTI 201
            .|..:|.|.....|.::||||.||.:.|..|||:|:|.|::.|.|.:.|...:.|:|||||:..:
  Fly   145 LYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAISNMPVKEVL 209

  Fly   202 RHASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTEFANMVV 266
            .|..||.   |.|..:.|:.||||||:||.|   |..|........|.:..|.:..:.:.|....
  Fly   210 AHGDLKT---TSFHTTPPISTYLVAFVISDF---GSISETYRGITQSIYTSPTSKEKGQVALKNA 268

  Fly   267 APLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAV 331
            ...::..||.|..:|...|:|.|||......:.|||||..:.:.:||   :..|.|.|:   |.:
  Fly   269 VRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLITYKDVNLL---KNISSDGQK---RKL 327

  Fly   332 AMM-----VVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDY 391
            .::     :.:||||||||..||...|:...||.|.|......:.|.....:........|...|
  Fly   328 DLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSY 392

  Fly   392 DAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATS 456
            ::..:...::..|..|..|...::.|..::.|.:.:|.|....::.::..:..:|..|....|..
  Fly   393 NSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYSVANE 457

  Fly   457 SDFWDLL--QLQVDRN-GRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQ 518
            .:.:|.|  :||.|.. ........|..||..|......|::.|||||::.|...:|
  Fly   458 LNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQ-------- 514

  Fly   519 FRNRWARNPCWWVPLSYT---CPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPT--DW 578
             |:...::..||:|:::.   .|:.:.:::..|         .|.....||.||.|....:  ||
  Fly   515 -RSVHMKDELWWIPINFATTQSPNFEDTQVDMF---------MPPQPQYTVSLEDLNIHVSGRDW 569

  Fly   579 ILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIE-YDMALG 642
            |:.|.|||..:.|.||..|...:.:.|  .....:||.:||..|..||..|....:|| .::...
  Fly   570 IMVNKQHTGFYLVRYDTDNLMAIARQL--QTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFE 632

  Fly   643 ILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRV-ISSDLTSSSGNM 706
            :|.|||.|::.:.|...:.:.|.:........:..:|..::|.|:...|:|| :...:..:...|
  Fly   633 LLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYVEQGVNLAEDGM 697

  Fly   707 THRPVIIRLACEYELPACVSLARREFMKGTPEK------GGWMTIRERETVVCTAVKFGTEGD-R 764
            ...  |:.:||..:||.|:...||...:...:|      ..:..|  .::|:|..|::.::.| :
  Fly   698 FRG--ILEIACSADLPECLEYTRRLAKEHIIDKIYFKDGSDYHAI--IDSVLCMGVRYLSDQDFQ 758

  Fly   765 DMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVSNSMGYR 829
            .:::.|.:....:...:.::.||.|:::    .|.|::..|                  ..||
  Fly   759 RIIDMMQEIDRASVYYDDIIYALRCTQS----HRHLLYYLE------------------GLMG-- 799

  Fly   830 LAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRD----MNGSERL 890
                             .|||..|          ||..::|:|....:|..|..    ....||.
  Fly   800 -----------------ENSTHMV----------LSEFEDLMYLLYIYKSNLASRPVIWQYIERN 837

  Fly   891 IKILLERGNDNIHW----------QRTKFRPMLQAI 916
            .|:|....|...|:          ||:.|..:.|.|
  Fly   838 YKVLCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTI 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	124/479 (26%)
		ERAP1_C	578..897	CDD:463368	72/331 (22%)
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	125/480 (26%)
		ERAP1_C	569..841	CDD:463368	71/328 (22%)