Protein Alignment CG2111 and lta4h

DIOPT Version :9

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_998451.1
• Gene: lta4h / 406575
• ZFINID: ZDB-GENE-040426-2477
• Length: 611
• Species: Danio rerio
• Alignment Length: 529
• Identity: 107/529 - (20%)
• Similarity: 192/529 - (36%)
• Gaps: 167/529 - (31%)

  Fly    60 SERSTKRIVLNAH---DLAIGKRR-AVT---LSDKNGNSVPVSSIQM---DIKLSRLTVSLK--- 111
            |:.|||.:.|..|   |..:.|.: |:|   |.||      .||:.:   |:|:|:::.:.:
Zfish    14 SKCSTKHLNLIYHVDFDRHVLKGKVALTVEVLEDK------FSSLTLDSKDLKISKVSANGQAAK 72

  Fly   112 -----------RPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNT----TLTQWLAA------ 155
                       .||::.:.:.:           :.|.:....:::.|    |..|||..
Zfish    73 FELGAKHKFKGSPLEITLPFEL-----------SRGQHVIVEIEYETSPTATALQWLTPKQTAGK 126

  Fly   156 ------TQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKD------ 208
                  :|.:..|.|...||.|.|..:          :.|.|..::|.:.....::|:|
Zfish   127 KHPYLFSQCQATHCRTMVPCQDTPSVK----------HTYYAQVSVPRELVALMSALRDGQEPDP 181

  Fly   209 ----YVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPIS-TWARPDALSQTEFANMVVAP 268
                .|..:|.:..||.:||:|.::...:       .|...|.| .|:..:.:.:..:.......
Zfish   182 SDSSRVIYRFRQPVPMPSYLIAIVVGALE-------SREIGPRSRVWSEKEYVDEAAYEFAETET 239

  Fly   269 LLSFYEDLFNSTYRQKKIDLVAL-PDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVA 332
            :|...|.| ...|...:.|::.| |.|.:...||..|.......|..|         :.:|..:|
Zfish   240 MLKTAESL-AGPYVWGQYDVLVLPPSFPYGGMENPCLTFVTPTVLAGD---------RSLAGVIA 294

  Fly   333 MMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPE----------WDYQERHALQLYLS 387
            ..:.:.|.||||:...|...||.....:|:.|.....:..|          |.       :|:.|
Zfish   295 HEISHSWTGNLVTNRTWEHFWLNEGHTVYIERMIARCMEGEQLRQFKGIGGWK-------ELHES 352

  Fly   388 VLDYDAH------------VNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLT 440
            |..:.|:            |:||...:|||        |    |:..|:|:.:...:.|.|.::.
Zfish   353 VKQFGANNVLTNLVPNLHEVDTDEAFSSVP--------Y----EKGFALLYHLEELMGGPEVFMG 405

  Fly   441 ALRRYLVVYANRTATSSDFW------------DLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYP 493
            .::.|:.::|..:.|:.: |            |:|. :||.|              .|:..||
Zfish   406 FVKSYIQLFAYGSVTTEE-WKNYLFTYFKDKVDILN-KVDWN--------------AWMHTPG-- 452

  Fly   494 LVTVTRNYD 502
            :..|...||
Zfish   453 MAPVRPQYD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	Peptidase_M1	25..421	CDD:279741	88/434 (20%)
		M1_APN_2	33..493	CDD:189008	104/518 (20%)
		ERAP1_C	579..897	CDD:288671
lta4h	NP_998451.1	leuko_A4_hydro	18..607	CDD:274120	105/525 (20%)
		M1_LTA4H	18..449	CDD:189006	100/509 (20%)
		Leuk-A4-hydro_C	467..606	CDD:286244

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900