Protein Alignment CG2111 and CG40470

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001036635.1
• Gene: CG40470 / 3355093
• FlyBaseID: FBgn0058470
• Length: 941
• Species: Drosophila melanogaster
• Alignment Length: 947
• Identity: 229/947 - (24%)
• Similarity: 405/947 - (42%)
• Gaps: 131/947 - (13%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHD---LAIGKRRAVTLSD 86
            ||||.::||||.|.|...::.  |.|.|::.:.||....:|::..:|||   :.:.:....||:.
  Fly    52 RLPKEVLPLSYEVLIEPHMDN--QNFEGSIRMHLRWIGDSKKVYFHAHDTLLIDVSQINLTTLNM 114

  Fly    87 KNGNSVPVSSIQMDIKLSR---LTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTT 148
            .:|.......|...::|.|   ..:.||..:|......:.:.|...:.....|.:.|.|.:....
  Fly   115 GDGTLDKNVIILRGVRLPRKPVFVLYLKDKIKKGSECLLDIYFQGNISETEEGLFRSYYTNSGND 179

  Fly   149 LTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQ 213
            ..:...||..:||:||..|||||:|..:.||.:::|.|..|..|.|.|:..||.|..|:.|....
  Fly   180 GEEIYLATNLKPNNARRLFPCFDEPGIKVPFNVSIARPKGYITLFNTPLHNTINHPKLRSYSLDF 244

  Fly   214 FVESHPMQTYLVAFMISK---FDRPGFTSSERSDCP-ISTWARPDALSQTEF------ANMVVAP 268
            |..:.||.|:...|:|.|   ::......|  ||.| |:.|:  :.||.|..      .|:....
  Fly   245 FHTTAPMSTHAFGFVILKLHMWNEHKIVKS--SDIPAINIWS--NNLSSTNLLDIQNKLNVAHTT 305

  Fly   269 LLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSI--DDQQGVARAV 331
            :..|    ||......|:|::|:|...       .||..:...:|. ::.|.|  .|...::|.
  Fly   306 IQHF----FNIPLPLTKLDVIAIPSLA-------TLPFISASGILI-ARESEILKKDVFEISRE- 357

  Fly   332 AMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVN 396
               ::.||.|..::..||.:..:......:::...|..:....::..::.:.:..| |.|:
  Fly   358 ---LIYQWIGIWITPEWWTDANVNKALISFIASEIVFEINGGIEFNGKYPMTILYS-LYYE---- 414

  Fly   397 TDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWD 461
               ::...|: |||....:|....|..::..||...:|:..:...::.::..|..:|..|||||:
  Fly   415 ---LSKRYPN-SHITGIKHEFASIKVQLIIRMLSLTVGKYTFRLGIQSFICDYKFKTYKSSDFWN 475

  Fly   462 LLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQ-----QRFFITPQFRN 521
            .:..|...:..|...|:|..|.:.||.....||||:.|:||..||||.|     :|....|.
  Fly   476 AITTQAKADNSLDSDLSILSIAESWLEHSRLPLVTIIRDYDSETAIVQQKVYLRERLHDVPD--- 537

  Fly   522 RWARNPCWWVPLSYTCPSCQHSEIISF-----SRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILF 581
              ..|..||:|:     :.:..:.:||     .:|:        :|:..:|:..|.:: ..:|:.
  Fly   538 --QDNMLWWIPI-----ALKRQDSLSFVNTGSFKWM--------NKTRQMLISNLPSK-NMFIIV 586

  Fly   582 NVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGY 646
            |.:...||.||||..||.:|:|.|....|...|....||:|:.|.::||::|::.:..||.:..:
  Fly   587 NEEEIGPFPVNYDDNNWNMLSKYLRTEEKRESIPVYTRAKLLHDAWNLAYAGELNFSTALNVTLF 651

  Fly   647 LEHEDEFVVWVATEISFERI-NNVAKSNPNYLIFKTYMRLLLERQFKRV----ISSDLTSSSGNM 706
            |::|...:||.......::: ..:.||:.|.. |:.|:..||...::.:    .:.|:     |:
  Fly   652 LKYERNHIVWSPVFTFLDQVGKRLEKSSINKK-FELYIIELLAPLYEYLGTAHFNEDI-----NI 710

  Fly   707 TH-RPVIIRLACEYELPACVSLARREFMKGTPEKGGWM--TIRERET-----VVCTAVKFGTEGD 763
            |. |.:.....|:.....|...|||.|       ..|:  :....||     .:|:..|:|:
  Fly   711 TELRKLTTSFLCKAGYFPCFKEARRAF-------NIWINSSFPNFETPVPNEYICSIFKWGS--- 765

  Fly   764 RDMVESM--------YKRSNFAAEKESLLTALA-CSRNVFALQRVLIWTFESSGVRKQ------- 812
              |.|.|        :.:|...:::..||..|| |     ..||..|:......:.|.
  Fly   766 --MKEWMFGLDRLCEFPKSRIQSDRTHLLKMLAGC-----PAQRDKIFILLELAILKNISIFSDT 823

  Fly   813 NARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFF 877
            :.......|.|.|:||.....::|.|..:|.:...|:|:....|::......||.:......||:
  Fly   824 DKMLIISTVTSRSIGYTTLLDFLSNNWDDIHHKFYNNTNIWTKLISSATGMFSTQEGYDLVKKFY 888

  Fly   878 KEILRDMNGSERLIKILLERGNDNIHWQRTKFRPMLQ 914
            .|.......::.:|:..|....:.|.|.:... |:::
  Fly   889 DEHYGHFGRAQHIIEKSLRNIKEGIQWSKQNI-PVIE 924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	113/471 (24%)
		ERAP1_C	578..897	CDD:463368	82/347 (24%)
CG40470	NP_001036635.1	GluZincin	60..502	CDD:472708	114/472 (24%)
		ERAP1_C	583..910	CDD:463368	82/349 (23%)