Protein Alignment CG2111 and LOC3290884

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_061503389.1
• Gene: LOC3290884 / 3290884
• VectorBaseID: AGAMI1_007830
• Length: 956
• Species: Anopheles gambiae
• Alignment Length: 919
• Identity: 237/919 - (25%)
• Similarity: 417/919 - (45%)
• Gaps: 98/919 - (10%)

  Fly    26 LPKWLVPLSYR--VDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKN 88
            |||...|::|.  :||.   |..:..:.|||.|..|.........||:..|.|. ..::.::..:
Mosquito    42 LPKVSEPINYNLFLDIT---NYDFYSYNGTVEITFRYTGDQNHFYLNSDGLVIA-TESIKVTGPD 102

  Fly    89 GNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWL 153
            |..|||:::....:..::....:..|:....|.:.::|.:.:..:..|.|.|:|...||  |::|
Mosquito   103 GTDVPVANVIYMEEFEQIYFGFRDRLQTGEQYKIAISFLNNIGTELKGLYRSSYKAGNT--TRYL 165

  Fly   154 AATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQFVESH 218
            |.|.||..:||..|||:|:|.::..|.:.:.|...||||||||   .|...::.||..|.|..:.
Mosquito   166 ATTHFESTYARSVFPCYDEPSYKATFNVKIRHRSEYRALSNMP---AINSVTVGDYTETTFDTTP 227

  Fly   219 PMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLSFYEDLFNSTYRQ 283
            .|.|||:||:||.|.    |.|..|| ....:|....::.|.:|...:...|...|:.|...|:.
Mosquito   228 LMSTYLLAFVISDFK----TLSHESD-RFRVFAAESKVAHTGYALEFLGNSLRTLENFFGRQYQL 287

  Fly   284 KKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAW 348
            .|:||:|:|||...:.|||||..|.|:.|:|:...::...:|.:|..:...:.:.||||.|:..|
Mosquito   288 PKVDLIAIPDFAMGAMENWGLITFREQYLIYEEGVTTARTKQNIADLITHELTHMWFGNEVTPEW 352

  Fly   349 WHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAA 413
            |..:||...||.|...:....|.|.|:..::..:....|.|..|.:.|..:::....:.:.:...
Mosquito   353 WTYLWLSEGFARYFEYYITSQLEPTWNLWQQFIVNNVHSALSQDCNSNNRMMSYYATNPAVLNDL 417

  Fly   414 YNEIGERKAAVLFEMLHRVMGEEAWLTAL------RRYLVVYANRTATSSDFWDLLQLQVDRNGR 472
            ::.:...|:|.:..|:..|:|.:.:..:|      |.||........||.:.:..:.|..
Mosquito   418 FDYVVYAKSASVIRMIQNVIGFDTFRQSLNDYLRSRSYLTTRPQYLYTSIEKFRTVDLPA----- 477

  Fly   473 LGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI-----TPQFRNRWARNPCWWVP 532
                 ::..|.:.|...||||:|||:.:...||...||:||::     ||      .:|..:::|
Mosquito   478 -----SVEVIFESWANTPGYPVVTVSIDRTTRTLTASQKRFWMPNEIDTP------PQNMLFYIP 531

  Fly   533 LSY--TCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDL 595
            ::|  ..|:....|..:.:.|||     |...:.||.||    ...:|::.|.|.|..:|||||.
Mosquito   532 VNYGSNVPTSTDFEDTTPTFWLT-----PQDPTATVTLE----AGVEWVVVNKQQTGYYRVNYDD 587

  Fly   596 RNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATE 660
            .:|..|.:.|........:..:||||||||:.:||.:|::.||:||.::.|||.|.|::.|....
Mosquito   588 ESWHKLIEVLNSDQFEDQLPVINRAQLVDDVANLARAGEVGYDVALSLMQYLERETEYIPWATAY 652

  Fly   661 ISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMT--HRPVIIRLACEYELPA 723
            .:...::.:..|:..|..|:|::|.:....::.::   ||.....::  ||...:.|||...:..
Mosquito   653 NALLYLDRMFSSHEEYSRFETFLRTITGCMYENIL---LTGPMDQISRLHRGNTVYLACYSGVKK 714

  Fly   724 CVSLARREFMKGTPEKGGWMTIRE--RETVVCTAVKFGT---EGDRDMVESMYKRSNFAAEKESL 783
            |:..|.....|...:..  .||.|  :.:|.|...|:.:   ....|:.|.....:|...:.:.:
Mosquito   715 CLDDAHALANKAVQDSS--FTIPEEVQASVFCALHKYPSATLNAQTDLFEKYVTSANSPEDLDMI 777

  Fly   784 ---LTALACSRNVFALQ---RVLIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNI 842
               |.::.|:||...::   .:|.:.:....|......:.:..:::.|.|.|.|.      :|.:
Mosquito   778 NRFLASVGCARNETIMEYYLTLLAYNYPGLPVTAGQRSQIYLGLINGSPGTRQAA------LQYL 836

  Fly   843 RNYCSNST---DKVVNLMTPLIECLSTPKELLYFSKFFKEILRDM---------NGSERLIKILL 895
            ..:.|..|   ..|..:.|.|...::|        :...|:|:::         ..::......|
Mosquito   837 YEHFSTVTYLLTSVTPIFTELGNRINT--------RLQHEVLKNIVDEYRHMLTTAAKAAADAAL 893

  Fly   896 ERGNDNIHW 904
            .:...||.|
Mosquito   894 VKAEQNIRW 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	124/461 (27%)
		ERAP1_C	578..897	CDD:463368	77/343 (22%)
LOC3290884	XP_061503389.1	None