Protein Alignment CG2111 and Lta4h

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 669
• Identity: 145/669 - (21%)
• Similarity: 232/669 - (34%)
• Gaps: 182/669 - (27%)

  Fly    52 GTVVIDLRSERSTKR-IVLNAHDLAI------GKRRAVTLSDKNGNSVPVSSIQMDIKLSRLTVS 109
            ||..:.::|:....| :.|:..||.|      |:....||.:..|           .|.|.:.:|
  Rat    37 GTAALTVQSQEDNLRSLTLDTKDLTIEKVVINGQEVKYTLGESQG-----------YKGSPMEIS 90

  Fly   110 LKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAA------------TQFEPNH 162
            |...|..|....:.::|.:               ...::..|||..            :|.:..|
  Rat    91 LPIALSKNQEVVIEISFET---------------SPKSSALQWLTPEQTSGKQHPYLFSQCQAIH 140

  Fly   163 AREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHA--------SLKDYVWTQFVESHP 219
            .|...||.|.|..:..:...::.|....||.:     .||..        |.|.|.:.|.|   |
  Rat   141 CRAILPCQDTPSVKLTYTAEVSVPKELVALMS-----AIRDGEAPDPEDPSRKIYRFNQRV---P 197

  Fly   220 MQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLSFYEDLFNSTYRQK 284
            :..||:|.::      |...|.:.......|:..:.:.::.:.......:|...||| ...|...
  Rat   198 IPCYLIALVV------GALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDL-GGPYVWG 255

  Fly   285 KIDLVAL-PDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAW 348
            :.||:.| |.|.:...||..|.......|..|...|::         :|..:.:.|.||||:...
  Rat   256 QYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNV---------IAHEISHSWTGNLVTNKT 311

  Fly   349 WHEIWLKNVFALYLSRFGVHSLRPEWDYQERHAL----QLYLSVLDY-DAHVNTDLVTASV---P 405
            |...||.....:||.|.....|..| .::..|||    :|..::..: ::|..|.||....   |
  Rat   312 WDHFWLNEGHTVYLERHICGRLFGE-KFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDP 375

  Fly   406 DESHIWAAYNEIG-ERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFW--------- 460
            |     .||:.|. |:..|:||.:...:.|.|.:|..|:.|:..::.::.|:.| |
  Rat   376 D-----VAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDD-WKSFLYAHFK 434

  Fly   461 ---DLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNR 522
               |||. |||.|              .||..||.|  .|..|||
  Rat   435 DKVDLLN-QVDWN--------------AWLYAPGLP--PVKPNYD-------------------- 462

  Fly   523 WARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTA 587
                    |.|:..|       |....||:|......:|.| ...|:.|.:...:..|..|...|
  Rat   463 --------VTLTNAC-------IALSQRWVTAKEEDLNSFS-IEDLKDLSSHQLNEFLAQVLQKA 511

  Fly   588 PFRVNY-----DLRNWQLLNKT----------------LADPNKFRLIHRVNRAQLVDDLFSLAW 631
            |..:.:     ::.|:..:|.:                .|.|...::.....|.:....||....
  Rat   512 PLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLA 576

  Fly   632 SGDIEYDMALGILGYLEHE 650
            :.|..:|.|  :..|.||:
  Rat   577 AFDKSHDQA--VRTYQEHK 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	108/483 (22%)
		ERAP1_C	578..897	CDD:463368	17/94 (18%)
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	145/669 (22%)