Protein Alignment CG2111 and ape2

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_595998.1
• Gene: ape2 / 2540648
• PomBaseID: SPBC1921.05
• Length: 882
• Species: Schizosaccharomyces pombe
• Alignment Length: 864
• Identity: 200/864 - (23%)
• Similarity: 367/864 - (42%)
• Gaps: 126/864 - (14%)

  Fly    26 LPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNGN 90
            |||.:.|:.|.:.:...:..  ..:||.||:.|.....:..|.|:..:|     |.:|.:.:.|
pombe    20 LPKNVKPIHYDLSLYPDLET--FTYGGKVVVTLDVLEDSNSITLHGINL-----RILTAALEWG- 76

  Fly    91 SVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAA 155
            |..|.:.::.....|:.:.....:..|....:.:.||:.:.:...|||.|:|||.:.. |::||.
pombe    77 SQTVWASEVSYGDERIVLQFPSTVPANSVAVLTLPFTARISSGMEGFYRSSYVDSDGN-TKYLAT 140

  Fly   156 TQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNM-PVQRTIRHASLKDYVWT-QFVESH 218
            ||.||..||.||||:|:|..:..|.|::.....|..|||| .|:.|:     ||.:.| :|.|:.
pombe   141 TQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAVEETV-----KDGLKTARFAETC 200

  Fly   219 PMQTYLVAFMISKFD-----RPGFTSSERSDC---PISTWARPDALSQTEFANMVVAPLLSFYED 275
            .|.|||:|:::::.:     .||      ..|   |:..:..|....|.:||..:.|..|.|:..
pombe   201 RMSTYLLAWIVAELEYVEYFTPG------KHCPRLPVRVYTTPGFSEQGKFAAELGAKTLDFFSG 259

  Fly   276 LFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWF 340
            :|...|...|.|:||:|||...:.|||||..:...::|. |:.|:....:.||..|...:.:|||
pombe   260 VFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILV-SEDSAATVIERVAEVVQHELAHQWF 323

  Fly   341 GNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASVP 405
            ||||::.:|..:||...||.::|.|..:...|||...|.:......|.|..||..::..:...:.
pombe   324 GNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYVTDNLQSALSLDALRSSHPIEVPIM 388

  Fly   406 DESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRN 470
            .:..|...::.|...|.:.:..|:.:.:||:.::..:::|:..:......:.|.|..|..:
pombe   389 HDYEINQIFDAISYSKGSCVIRMVSKYVGEDTFIKGIQKYISKHRYGNTVTEDLWAALSAE---- 449

  Fly   471 GRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSY 535
                .|.:|:..|..|..:.|||:::|:...|.. .::.|.||..|...:.. .....:|.||
pombe   450 ----SGQDISSTMHNWTKKTGYPVLSVSETNDGE-LLIEQHRFLSTGDVKPE-EDTVIYWAPL-- 506

  Fly   536 TCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLE-----KLEAEPTDWILFNVQHTAPFRVNYDL 595
                          :..|....|.......||.:     |::.|..:....|.:.:..:||||..
pombe   507 --------------KLKTMKDGKAVVDEKAVLSDRSKKIKVDKEALESYKLNSEQSGIYRVNYSA 557

  Fly   596 RNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVW---- 656
            .:.:.|::...:...:..:.  :||.|:.|:.||:.:|..:....|.::...:.|..|||:
pombe   558 DHLKKLSQIAVEKPDYLSVE--DRAGLIADVASLSRAGYGKVSSTLDLIKTWKDEPNFVVFAEML 620

  Fly   657 -----VATEISFERINNVA---------------------KSNPNYLIFKTYMRLLLERQFKRVI 695
                 :.:.:.||..:.:|                     |:|.:::|          ||||
pombe   621 ARLNGIKSTLRFESSDIIAAMKKLVLEVSATKAHSLGWEFKANDDHII----------RQFK--- 672

  Fly   696 SSDLTSSSGNMTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRE--RETVVCTAVKF 758
             |.:.:.:|......|:.....:::..|               .|....|.:  |..|...|:::
pombe   673 -STVYNYAGLFGDDKVVKDALSKFDAYA---------------SGNKSAINDNLRSAVFNIAIRY 721

  Fly   759 GTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVS 823
            |.....|.:..:|.::|....:.|.|.|...:.:...:|:.|..|.:.. |::|:.......:.:
pombe   722 GGAKSWDQLLEIYTKTNDPYVRNSCLRAFGVTEDEKYIQKTLDLTLDPI-VKEQDIYLILVTLST 785

  Fly   824 NSMGYRLAKKYVSVNMQNI 842
            :..|.....|:.:.|...:
pombe   786 HKNGVLAMWKFATSNWDKL 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	125/463 (27%)
		ERAP1_C	578..897	CDD:463368	52/297 (18%)
ape2	NP_595998.1	M1_APN-Q_like	27..463	CDD:341064	126/464 (27%)
		ERAP1_C	541..858	CDD:463368	52/296 (18%)