Protein Alignment CG2111 and T12E12.6

DIOPT Version :9

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 150/660 - (22%)
• Similarity: 249/660 - (37%)
• Gaps: 177/660 - (26%)

  Fly    27 PKWLVPLSYRVDIVTRIN-QPYQPFGGTVVIDLRSERSTKRIVLNAHDL----AIGKRRAVTLSD 86
            |..::||||  |::.::. ..:..|.|::|:.......:..|.|:|.||    .|...|:..|::
 Worm    19 PHNIIPLSY--DLLFKLPIHEFNGFTGSMVLHFNLSSLSDNITLDAVDLHSFRNISLIRSADLTE 81

  Fly    87 KNGNSVPVSSIQMDIKLSR--------LTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYV 143
            ....|:.:...::::|..:        ||:.         .|:.|:           |..|....
 Worm    82 PTLKSIKILKEKVELKFEKSLFPGQYLLTIG---------EYNGRI-----------GNSSEALF 126

  Fly   144 DHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIR---HAS 205
            :....|   |..|..:|||||..|||.|.|..:..|::::.||....|.||     ||.   |..
 Worm   127 ERRNPL---LYTTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTDTVAQSN-----TIAMDVHVE 183

  Fly   206 LKDYVWTQFVESHPMQTYLVAF--------MISKFDRPGFT----SSERS------DCPISTWAR 252
            .:.:..|.|..:..:..|||||        .:|:....|.|    ...|.      ||
 Worm   184 NRKWQRTIFQATPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVRVNGESRGLVLRVLDC------- 241

  Fly   253 PDALSQTE-FANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDS 316
              ||:..| .|.::..||            ...|||.:.:|::. ...||||....:|      :
 Worm   242 --ALASFEILAGLIDVPL------------PLNKIDFILVPEYD-GGMENWGHITVSE------T 285

  Fly   317 QRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHA 381
            ..:|.||.. :...:|..:.:.|.||..::..|:.|.|:.....:::...|.:|..:....:|..
 Worm   286 LATSGDDAH-LIYLIAHEIAHHWIGNRATIDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQ 349

  Fly   382 LQLYLSV------------LDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMG 434
            |..|:.:            |...:.:|.:|:      ..|.:.        |..||.:.|..|:|
 Worm   350 LAQYVEIQLVEDFLSPGHSLYMPSKINQELI------NRHCYL--------KGVVLLDTLESVVG 400

  Fly   435 EEAWLTALRRYLVVYANRTATS-SDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVT 498
            |:...:.::..:..::....|: :.::|  |::||||..:|      :|.:.|....|||.:.|.
 Worm   401 EQFMYSVIKSLVGSHSTYNLTTFTSYFD--QIRVDRNATVG------QIYEYWYTTGGYPSILVE 457

  Fly   499 RNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYT----CPSCQHSEIISFSRWLTCPTSKP 559
            .|               .|..|.:....|.|  ||..|    .|....||.|.|:.
 Worm   458 NN---------------GPSSRLQQLSRPLW--PLKMTSTLAIPQFVFSESIVFAS--------- 496

  Fly   560 SSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVD 624
                        |..|   :|.|:..|:..|||||...|..:.|.:.:..:  |...|.|||||.
 Worm   497 ------------ENAP---LLVNLNFTSFMRVNYDSLTWTAIFKYMFEEPE--LFSAVGRAQLVS 544

  Fly   625 DLFSLAWSGD 634
            | |...::.|
 Worm   545 D-FCYFYAND 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	Peptidase_M1	25..421	CDD:279741	94/440 (21%)
		M1_APN_2	33..493	CDD:189008	110/507 (22%)
		ERAP1_C	579..897	CDD:288671	20/56 (36%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:387391	98/449 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920