Protein Alignment CG2111 and anp-1

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001041160.1
• Gene: anp-1 / 179763
• WormBaseID: WBGene00011587
• Length: 988
• Species: Caenorhabditis elegans
• Alignment Length: 968
• Identity: 235/968 - (24%)
• Similarity: 412/968 - (42%)
• Gaps: 141/968 - (14%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQP------------FGGTVVIDLRSERSTKRIVLNAHD---- 73
            |||..:.|:||::.:.|     |.|            |.|.|:|:|...:|.|::.||:.|
 Worm    85 RLPTSVSPISYQLTVKT-----YLPGYGYTADKNNLTFEGQVLIELNITKSIKKVSLNSKDLNYT 144

  Fly    74 ---------LAIGKRRAVTLSDKNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSV 129
                     |..||..|.||.||....            .::..:|...::...:.:::|||.:.
 Worm   145 EEFIKKSSILVNGKSIAFTLDDKQSTH------------EKIFFNLDETVEPTTSATLKVAFGAP 197

  Fly   130 LRNDNTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSN 194
            ||.|.:|.|.:.|.:.... ::..|.||.||.:||...||||:|.::..:.:.:.||....|:||
 Worm   198 LRTDMSGLYQTTYTNSKGE-SKMAAVTQMEPVYARRMVPCFDEPAYKATWTVTVIHPNKTVAVSN 261

  Fly   195 MPVQRTIRHASLKD--------YVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWA 251
                      .::|        ::.:.|..:..|.:||:|..||:|:....|:  :|......|:
 Worm   262 ----------GIEDKVEDGQPGFIISTFKPTPRMSSYLLAIFISEFEYNEATT--KSGVRFRVWS 314

  Fly   252 RPDALSQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDS 316
            ||:..:.|.:|.......|.:||..:|.::...|.|:||||||:..:.|||||..:.|.:||||.
 Worm   315 RPEEKNSTMYAVEAGVKCLEYYEKYYNISFPLPKQDMVALPDFSAGAMENWGLITYRESALLYDP 379

  Fly   317 QRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRP------EWD 375
            :..|...::.||..:|..:.:|||||||::.||:::||...||..:...|...:..      ||
 Worm   380 RIYSGSQKRRVAVVIAHELAHQWFGNLVTLKWWNDLWLNEGFATLVEYLGTDEISDGNMRMREW- 443

  Fly   376 YQERHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLT 440
                ..:....|.|..|:..:|..:|..:.....:..:::.:...|...:..|:.:.:|||.:.|
 Worm   444 ----FTMDALWSALAADSVASTHPLTFKIDKAMEVLDSFDSVTYDKGGAVLAMVRKTIGEENFNT 504

  Fly   441 ALRRYLVVYANRTATSSDFWDLLQLQVDRN--GRLGKGLNITRIMKCWLGQPGYPLVTVTR-NYD 502
            .:..||..:....|.:.:....|..::..:  |..|..|||:..|..|..|.||||:..:| |..
 Worm   505 GINHYLTRHQFDNADAGNLLTALGEKIPDSVMGPKGVKLNISEFMDPWTKQLGYPLLNASRINNT 569

  Fly   503 HRTAIVSQQRF--FITPQFRNRWARNPCW---W-VPLSYTCPSCQHSEIISFSRWLTCPTSKPSS 561
            |  .||.|.||  ..|.:...::: ||.|   | ||:.|........|:    :|:
 Worm   570 H--IIVEQSRFKLLATGKEEEKYS-NPVWGFKWDVPVWYQVVGSSELEM----KWM--------- 618

  Fly   562 KSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDL 626
            |.|..|:.|.:..    ::.|.:....:|..|....|:.:::.|.:.::  ......|.:|:||.
 Worm   619 KRNEPLIIKSDKN----VIINAESNGFYRAGYSSGLWKEISEMLKENHE--QFSPQTRVRLIDDS 677

  Fly   627 FSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQF 691
            |:||.:|.:.|.:.|.::.||::|.|::.|.........:.::..|||...|...:|..|.|...
 Worm   678 FALARAGLLSYSIPLNLITYLKNEKEYLPWSGAIAKIRELIDMYGSNPEKDIVNKFMIALAENAP 742

  Fly   692 KRVISSDLTSSS-----------------------GNMTHRPVIIRLACEYELPACVSLARREFM 733
            .| .|.|..|.:                       |:...:..::::..|..|..|.:.......
 Worm   743 AR-RSIDFVSKNYLDEKKFYEVGAAQQIILNSCGFGDSVCQADMVKMFTEEVLAKCDATRILSEC 806

  Fly   734 KGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQR 798
            ...|..       .|....|.||:.|.....:.|...||......||.:|:|||.||:::..|::
 Worm   807 SQIPAP-------FRAESYCEAVRNGNSDTFEKVFHWYKTERNQVEKLNLMTALTCSKDILTLKK 864

  Fly   799 VLIWTF--ESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLI 861
            :|:...  |.|..|.|:....|..:.||.........::....::::...:........:::.::
 Worm   865 LLLDAMKPEGSSFRLQDCAALFAKISSNDATTDAMLNFLIDRWEDMQKRLATDHSGFSRVLSSIV 929

  Fly   862 ECLSTPKELLYFSKFFKEILRDMNGSERLIKILLERGNDNIHWQRTKFRPMLQAIRDI 919
            ..|.|...|....||.|:..:   .||..:..:.|.....:.|:.|..:.:.:.|.:|
 Worm   930 NTLKTRGGLDQLRKFRKKAPK---ASEFGLDKMEESAEVTVTWRETNLKFVTKIIEEI 984

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	129/494 (26%)
		ERAP1_C	578..897	CDD:463368	69/343 (20%)
anp-1	NP_001041160.1	M1_APN-Q_like	93..554	CDD:341064	130/495 (26%)
		ERAP1_C	632..953	CDD:463368	67/333 (20%)