Protein Alignment CG2111 and Y42A5A.1

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_505820.1
• Gene: Y42A5A.1 / 179536
• WormBaseID: WBGene00012776
• Length: 1045
• Species: Caenorhabditis elegans
• Alignment Length: 969
• Identity: 219/969 - (22%)
• Similarity: 416/969 - (42%)
• Gaps: 145/969 - (14%)

  Fly    12 LFFHLEANKTAVGRLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAI 76
            |:.|:. |.....::|:..:||.|.|::  ::..|::|     .|...|:..:.:..:..|..:.
 Worm   140 LYVHIN-NTNHRLQIPQIHIPLLYEVEL--KLFVPWRP-----TISFGSDNFSVKGHVRVHFTSG 196

  Fly    77 GKRRAVTLSDKN---GNSVPVSSIQMDIKLSR--------LTVSLKRPLKVNVTYSMRVAFTSVL 130
            |..|.:..||..   |:.|....:..:|.:..        |.::|:..:...:.|::.|||.|.:
 Worm   197 GGSRILLHSDSKQHIGDCVVRDELNRNITVKLVGRQYSQILDLNLETDMIHGMNYTLDVAFKSAI 261

  Fly   131 R-NDNTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSN 194
            . |...|.:::.|...|.  |:::.|||.:.:.||..|||.|.|..:..|...:.||....:::|
 Worm   262 NLNLAYGLFAAPYTFENE--TRYVVATQLQISEARTVFPCIDVPDMKAQFDTVIIHPTGTTSIAN 324

  Fly   195 MPVQRTIRHASLKDYVW--TQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALS 257
            |     :.:::..|..|  |.|..:.||.|||.||.:|  |.|...:..........:..|..|.
 Worm   325 M-----MENSTKVDGEWTTTTFHRTPPMSTYLFAFSVS--DYPYLETFSGRGVRSRVYCDPTKLV 382

  Fly   258 QTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSID 322
            ..:.....:.|:|.||||.|...|..:|:|:|.:|..:..:.|||||....:.:.||...|.:|.
 Worm   383 DAQLITKSIGPVLDFYEDYFGIPYPLEKLDVVIVPALSVTAMENWGLITIRQTNGLYTEGRFAIS 447

  Fly   323 DQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSL-RPEWDYQERHALQLYL 386
            .:..|...||..:.:|||||||::.||:::||...||..:|...|..| ...|.|::..|....:
 Worm   448 QKHDVQEIVAHELAHQWFGNLVTMKWWNDLWLNEGFATLISVRAVDFLENTTWRYEDSSAESQCV 512

  Fly   387 SVLDYDAHVNTDLVTASVP---DESHIWAAYNEI-GE----RKAAVLFEMLHRVMGEEAWLTALR 443
            :       :..|.:.:..|   .::..:.:|.|| |:    :|:|::..|:.|::.|:.:...|:
 Worm   513 A-------LRADQIDSISPVSGKKNSNFDSYMEIQGKAIIYKKSAIIIRMIERLVEEDIFRQGLK 570

  Fly   444 RYLVVYANRTATSSDFWDLLQLQVDRN--GRL-GKGLNITRIMKCWLGQPGYPLVTVTRNYDHRT 505
            |:|..:..:.|...|.:::|....|.:  |.| |:..:::.:|..|:.|..:|::.|.|. :...
 Worm   571 RFLNTFLYKNADHEDLFNVLVYVHDSSAGGHLRGQNFSLSDVMDTWIRQAHFPVIHVNRK-EGSL 634

  Fly   506 AIVSQQRFFITPQFRNRWARNPCWWVPLSYTCP-SCQHSEIISFSRWLTCPTSKPSSKSNTVLLE 569
            ..:.|:::...|:..   .....|.:|:.|..| |.:|...     |||....|.......::::
 Worm   635 VTLRQEKYEHVPRDE---PEKQVWKIPIFYDDPVSGKHKVF-----WLTDTQPKVFDMGGLLVVD 691

  Fly   570 KLEAEPTDWILFNVQHTAPF-RVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSG 633
                          .|...: |:.||:..:..:...|.|  .|.:|...:|::|:||..::|.:|
 Worm   692 --------------PHQLTYMRLRYDMEMYSDITMALMD--DFTMIPTNSRSRLIDDTLAMAENG 740

  Fly   634 DIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSD 698
            .:.|.:...:..|:..|..:..:.......:........:..:.|:|.|:.|::...|.:..:..
 Worm   741 QLTYKVPFNLTMYMSREIAYRPFQTFSAYLDFFLPRMYIHEGWSIYKKYLELVVGIPFDKFNAEG 805

  Fly   699 LTSSSGNMTH----RPVIIRLACEYELPACVSLARREFMK------GTPEKGGWMTIRE-----R 748
            |..|..:.|.    |.:::..||..|...||.:|::.|.:      |..:....|...:     |
 Worm   806 LDVSFDHNTDLFHTRQIVVFRACGIEYEPCVRMAKQRFAELRVNCSGENQLLSGMECNKIPYYLR 870

  Fly   749 ETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQN 813
            ..|...|:..||:.|.|.:...:...::..|.:::.|.| |:.|:                 ::|
 Worm   871 PHVYSAAINDGTQEDFDFLYKKWMIEHYMMEHDNIFTGL-CTTNI-----------------REN 917

  Fly   814 ARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFK 878
            :.|.::.|:.|.     |::.|.|..|    .||....|...::..|.|      :.:|..:|..
 Worm   918 SDRAWRQVIKNG-----ARENVMVRAQ----LCSKKLSKNNFILDLLYE------DKVYLKEFVD 967

  Fly   879 E-----------ILRDMNGSERLIKILLERGNDNIH--WQRTKFRPMLQAI-RDIILWR 923
            :           :.|.:|..|.::|.      |.:.  :.:.::.|.|:|| .|.:.||
 Worm   968 KDRKSLFALQQLLYRKINYEEEVLKA------DEVFKPYPQLRWIPKLRAIASDRLDWR 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	123/479 (26%)
		ERAP1_C	578..897	CDD:463368	66/345 (19%)
Y42A5A.1	NP_505820.1	M1_APN-Q_like	160..618	CDD:341064	124/480 (26%)
		ERAP1_C	687..>939	CDD:463368	54/290 (19%)