Protein Alignment CG2111 and AC3.5

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 999
• Identity: 231/999 - (23%)
• Similarity: 394/999 - (39%)
• Gaps: 200/999 - (20%)

  Fly    26 LPKWLVPLSYRVDIVTRINQPYQPFG----GTVVIDLRSERSTKRIVLNAHDLAIGK-------- 78
            |||.:.|:.|.|.:..::.      |    |...:.|..|..|.:|||||.|:...:
 Worm   156 LPKNVQPVWYDVSLSPKVG------GNGTMGLAHVKLNIEEPTNKIVLNAKDIEFTRNLEKIQLS 214

  Fly    79 ----RRAVTLSDKNGNS-------------------------VPVSS----------IQMDIKLS 104
                :||....|...||                         .||||          |:.|..|.
 Worm   215 KEVTKRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSFVDTGIKVTNIEFDENLE 279

  Fly   105 RLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPC 169
            ::|::|.:.||...|..:::.|||.:.|:| |.....| .::....|.:..||...::.|..||.
 Worm   280 KVTLTLDQELKKGSTVVLKIPFTSKVSNNN-GLKEYKY-KNSEGKEQSMFTTQPSYSYLRHVFPS 342

  Fly   170 FDDPIFRTPFKINLAHPYLYRALSNMPVQ---------RTIRHASLKDYVWTQFVESHPMQTYLV 225
            ||...|:.|..|.|.|......::|..|:         .|:......|:|....|.|....|
 Worm   343 FDQEAFKAPAAITLMHSKGSIVVANTGVKTKDDGDAQTSTLNKVLDPDFVIGDLVASEVNTT--- 404

  Fly   226 AFMISKFDRPGFTSSERSDCPISTWARPDALSQTE----FANMVVAPLLSFYEDLFNSTYRQKKI 286
                             |...|..|.||:....||    :||..:..:    |.:..|....|.:
 Worm   405 -----------------SGITIRIWTRPEVKHSTEQSLDYANQAIDAM----EHILQSRLESKSL 448

  Fly   287 DLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHE 351
            |:||:|.|...::.:.......||.:||:.|.:.|:.:..:||.::..:..||||.:.:...:..
 Worm   449 DIVAVPGFQTGNRVSPSFIVLPEEDILYNEQSNDINQKTRIARMISNRIAAQWFGGITNPEEFGT 513

  Fly   352 IWLKNVFALYLSRFGVHSLR--------PEWDYQERHALQLYLSVLDYDAHVNTDLVTASVPDES 408
            .||......:|.   |.:|.        ..|.|:....|:...:.......|.....:|.:.:..
 Worm   514 FWLNEALPRFLE---VEALEKILDINSDDLWTYEMEKILERDATATSQPLRVKNVFSSADIAEID 575

  Fly   409 HIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRL 473
            |.:     ||::.|||| .|:.:.:|...:..|:|.::..|.:........|...:..:  .|:|
 Worm   576 HEF-----IGKKGAAVL-RMIQKSVGVNVFNKAIRSFVSSYRSAYPYDDGLWKSFEKAL--GGKL 632

  Fly   474 GKG-----LNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRF---------FITPQFRNR-- 522
             ||     |::.:.:..|:.|.|:|||:|.: .|..|..:||:||         |   :|||.
 Worm   633 -KGWNNEPLDVAKFVNTWVDQIGFPLVSVEK-LDDETVELSQERFKNDHKTKEQF---KFRNAKY 692

  Fly   523 WARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTA 587
            |..   |.|||     ..:.|..:....||......|.:.|:::.|             |.....
 Worm   693 WFN---WEVPL-----FLKSSGPVGNVSWLHEAFRLPLNTSDSIYL-------------NTDSNG 736

  Fly   588 PFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDE 652
            .:||||:.:.|..:.|.| :.:..:|..| .||:|:.|:|:||.||.:.::.||.:..||..|..
 Worm   737 VYRVNYEEKRWNDIAKQL-EKSHGKLSER-TRARLISDVFALANSGALPFETALNVTSYLPMETA 799

  Fly   653 FVVW-VATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTHR------- 709
            .|.| :||.| |:::....:..|......:::...:.::|:.:.||...:||..:.:|
 Worm   800 TVPWLIATRI-FKKLTERLEGAPIQDKLNSFIYQKIHKKFEEISSSPGEASSNYLKNRLYANLLD 863

  Fly   710 -PVIIR----------LACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKFGTEGD 763
             ..|::          |..|..|..|....  .|.....|..|.:    ||.|.|..|:||.:..
 Worm   864 LMAIVKPEKSNEKLNELFVEGFLAPCQFSG--NFSSDCSEVPGDL----REKVYCNGVEFGNDTV 922

  Fly   764 RDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSG-----VRKQNARRTFKAVVS 823
            .:.|..:.::....|||:.|..:|||.|:..||:|:::....|:.     :||.|:|
 Worm   923 FETVRELAEKEVDGAEKDLLQNSLACFRDPRALRRLILDNLNSTSTVTLLLRKMNSR-------- 979

  Fly   824 NSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRDMNGSE 888
             .:|..:|..::..|...:......:..:.:|.:......|...:|......|.:...:..:|.|
 Worm   980 -PVGKEIATNWIIDNWSTVLKKKFKNDPETLNAIADAGIILDNEREKSMIETFMEHHHKSTHGIE 1043

  Fly   889 RLIKILLERGNDNIHWQRTKFRPM 912
            .|.| .:|....:|:|::.|...:
 Worm  1044 SLDK-KIEEATTDIYWRKQKINEL 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	115/530 (22%)
		ERAP1_C	578..897	CDD:463368	80/342 (23%)
AC3.5	NP_001256214.1	GluZincin	165..651	CDD:472708	116/529 (22%)
		beta-trefoil_FSCN-like	<685..741	CDD:483951	17/79 (22%)
		ERAP1_C	728..1056	CDD:463368	82/359 (23%)