Protein Alignment CG2111 and ltah-1.2

DIOPT Version :9

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_500385.1
• Gene: ltah-1.2 / 177123
• WormBaseID: WBGene00022610
• Length: 625
• Species: Caenorhabditis elegans
• Alignment Length: 683
• Identity: 139/683 - (20%)
• Similarity: 243/683 - (35%)
• Gaps: 188/683 - (27%)

  Fly    21 TAVGRLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLS 85
            ||:    ||.|....::.|            |...:..|......::||:..||:|
 Worm    27 TAI----KWTVSFQLKMII------------GQATLRCRCLTDATKLVLDVRDLSI--------- 66

  Fly    86 DKNGNSVPVSSIQMDIKL---------SRLTVSLKRP-------LKVNVTYSMRVAFTSVLRNDN 134
                .||.::.:..|.::         |:::|.|...       |:|.|.|.
 Worm    67 ----RSVSINGVDCDFRIAPNVYTFFGSKMSVYLPPQFQKAGTILQVTVAYG------------- 114

  Fly   135 TGFYSSNYVDHNTTLTQWLAA------------TQFEPNHAREAFPCFDDPIFRTPFKINLAHPY 187
                    ...:.|..||:..            :|.:..|||...||.|.|..::.::..:..|.
 Worm   115 --------TSPDATALQWMKKEQTADKRMPYLFSQCQAIHARSIVPCMDTPSVKSTYEAEVTVPT 171

  Fly   188 LYRALSNMPVQRTIRHASLKDYVWTQFVESHP--MQTYLVAFMISKFDRPGFTSSERSDCPISTW 250
            ....|.:     .|...|..|...|.|....|  :.:||:|.::...::...  |:|  |.:  |
 Worm   172 GMTCLMS-----AIGQGSKGDDDTTTFFYKQPVAIPSYLIAIVVGCLEKRDI--SDR--CAV--W 225

  Fly   251 ARPDALSQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVAL-PDFTFKSKENWGLPAFAEESLLY 314
            |.|..:.:..:.......:|:..|::... |...:.|:|.| |.|.|...||..| .|...:|
 Worm   226 AEPSVVDKAHWEFAETEDILASAEEIAGK-YIWGRYDMVCLPPSFPFGGMENPCL-TFLTPTL-- 286

  Fly   315 DSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQER 379
                  |...:.:...:|..:.:.|.||||:.:.|...||...|.:::.|.....|..| ||::.
 Worm   287 ------IAGDRSLVSVIAHEIAHSWSGNLVTNSSWEHFWLNEGFTMFIERKICGRLVSE-DYRQF 344

  Fly   380 HALQLYLSVL---DYDAHVNTDLVTASVPDESHI--WAAYNEIG-ERKAAVLFEMLHRVMGEEAW 438
            .|...:.:.|   .|:....|...|..:.|.:::  ..|::.:. |:.:|:||.:..::.|.|.:
 Worm   345 MAFNGWTNSLIPAVYEQFTPTHQFTKLIQDHTNVDPDVAFSCVPYEKGSALLFYLEQKLGGSEIF 409

  Fly   439 LTALRRYLVVYANRT--------------ATSSDFWDLLQLQVDRNG------RLGKGLNITR-- 481
            ...|:.||..:|::.              |...:..|.:...:..||      :...|.::..
 Worm   410 EAYLKDYLKTFAHQAIDSWQWKDHLYKYFADQKEVLDTVNFDLWFNGVGMPPEKPNYGQSMVEAC 474

  Fly   482 --IMKCWLGQPGYPLVTVTRNYDHRTA--IVSQQRFFITP-----QFRNRWARNPCWWVPLS--- 534
              ::|.||..            |..|.  |.|:..:.:.|     .....|..:|    |:.
 Worm   475 EVLLKKWLAA------------DESTVGDITSEDYYAMQPLQQIELLSQLWQHDP----PIEHYK 523

  Fly   535 -------YTCPSCQHSEIISFSRWL-TCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPF-R 590
                   |.....|:||::  ..|| .|..||         .|:...:..|::  |.|....| |
 Worm   524 LDALNKLYKLNDSQNSELL--LNWLRLCIKSK---------WEECIPKALDFV--NSQGRLKFCR 575

  Fly   591 VNY-DLRNWQLLNKTLADPNKFRLIHRVNRAQL 622
            ..| ||..|.:.||      |.|.::...|:|:
 Worm   576 PIYRDLAQWPIANK------KARDVYLKGRSQM 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	Peptidase_M1	25..421	CDD:279741	87/432 (20%)
		M1_APN_2	33..493	CDD:189008	101/520 (19%)
		ERAP1_C	579..897	CDD:288671	14/46 (30%)
ltah-1.2	NP_500385.1	M1_LTA4H	12..455	CDD:341062	100/499 (20%)
		Leuk-A4-hydro_C	500..614	CDD:378127	29/126 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910