Protein Alignment CG2111 and T16G12.1

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_499230.2
• Gene: T16G12.1 / 176416
• WormBaseID: WBGene00011803
• Length: 1890
• Species: Caenorhabditis elegans
• Alignment Length: 1001
• Identity: 238/1001 - (23%)
• Similarity: 395/1001 - (39%)
• Gaps: 203/1001 - (20%)

  Fly    19 NKTAVGRLPKW--------LVPLSYRVDIVTRI--NQPYQ-----PFGGTVVIDLRSERSTKRIV 68
            |...:|:.| |        :.|. |::|:...|  :.|||     .|..|..:..:....|..|.
 Worm   983 NLVVIGKTP-WEKTPNIDAVFPY-YKLDLQVNIPGSGPYQWYENMTFSATSTVTFQLVSPTSSIT 1045

  Fly    69 LNAHDLAIG--KRRAVTLSDKNGNS-VPV--SSIQMDIKLSRLTVSLKRPLKVNVT-----YSMR 123
            :|||.|...  ..|....:|:|.:: :|:  |.:..|.....:|:    |...|..     ||:.
 Worm  1046 INAHRLMFDPVSIRLYNENDENAHTPIPIDFSKVMKDYDKGTVTI----PTMNNTVLYPNQYSLF 1106

  Fly   124 VAFTS-VLRNDNTGFYSSNYVDHNTTLTQWLAATQFE--PNHAREAFPCFDDPIFRTPFKINLAH 185
            :.:|. :.:|.:.|..|:.|:........|:..|.||  |. ||...||:|:|.::..|::::.|
 Worm  1107 IEYTGFIFQNPDEGDASNTYLGGLNNRKGWIFTTDFEGGPG-ARSLLPCWDEPSYKGQFEVSVFH 1170

  Fly   186 PYLYRALSN-MPVQRTIRHASLKDYVW--TQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPI 247
            |....|||| :.:||||     .|..|  |:|..::.|.|||:|..:..|.  ...:..|:....
 Worm  1171 PTDMIALSNEVDIQRTI-----YDNGWTTTKFATTNQMSTYLLALCVGHFS--NLATVTRTGVLT 1228

  Fly   248 STWARPDALSQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFK--SKENWGLPAFAEE 310
            ..|.........|||..|.|..:.|.|:.|:..:..||:|::|||::|..  :.||||| ...|.
 Worm  1229 RVWTWSGMEQYGEFALNVTAGTIDFMENYFSYDFPLKKLDVMALPEYTMNAGAMENWGL-IIGEY 1292

  Fly   311 SL-LYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEW 374
            || ::|...::..|...||...|..||:||||::|::.||::|:|...||.|....|:.:..|
 Worm  1293 SLFMFDPDYATTRDITEVAETTAHEVVHQWFGDIVTLDWWNDIFLNEGFAQYWFANGIDNTFP-- 1355

  Fly   375 DYQERHALQL-----YLS--VLDYDAHVN-TDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHR 431
               |:||..:     |::  .|.||.... ...|.:..|....|...|      |.:.|..:|:.
 Worm  1356 ---EQHAYSIDYNRFYMNHIALKYDCIPGVAKPVISDTPPVFGIEPYY------KGSALLNLLNN 1411

  Fly   432 VMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRL---GKGLNITRIMKCWLGQPGYP 493
            |:....:...|..||..|....|:..:.|..|.:...|:...   |:.|:::..|..:..|..||
 Worm  1412 VLTPAVFQEGLSSYLTQYGYVNASPRNLWTSLTVAAQRHNITDWNGQPLDVSSFMDPYTLQTSYP 1476

  Fly   494 LVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSK 558
            ::|:|.. ...|...:||         :..:....|.|||....|..     :.|: |....|
 Worm  1477 IITLTLR-GTSTVQANQQ---------SCMSDETLWNVPLFTQTPGA-----LDFN-WFVNFT-- 1523

  Fly   559 PSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLV 623
              ..::...|..|   ||.:.:.|...|:..|:|||.::|..:...|.  :....:....||.|:
 Worm  1524 --GGNDATWLRPL---PTGYRVDNAGSTSFARINYDDKSWYSIQAQLL--SNMNTMSSTTRAMLL 1581

  Fly   624 DDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNP------NYLIFKTY 682
            ||......||..|....|.:..||.:||....|......|..:.|..:..|      ||:|..|
 Worm  1582 DDANFFYQSGRWEMTKFLDLTLYLVNEDSLAPWEQAIEFFTEMLNRFQYQPEIDTVRNYVIQIT- 1645

  Fly   683 MRLLLERQFKRVISSDLTSSSG-------------------NMTHRPVIIR------LACEYELP 722
                     |..:|....:::|                   |...|.|.:.      |.|:|.|
 Worm  1646 ---------KNAVSKFQWNTNGLWANDRIVQLLVNVNNLAVNRQSRQVALTLFNNFVLKCKYSL- 1700

  Fly   723 ACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKFGTE-GDRDMVESMY-----KRSNFAAEKE 781
                       .||.:..| :....|:...|..::.... .|...|.::|     .......:..
 Worm  1701 -----------SGTGKCSG-IHPNLRQPTYCYGLRQSNNIDDFTTVNNLYSWFVQNAGYLQTDGS 1753

  Fly   782 SLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYC 846
            :||.||.|.:|: .||:.::                 ::::|......|... ::|:
 Worm  1754 NLLNALGCVQNL-DLQKTML-----------------RSILSGDYPPSLLNS-IAVH-------- 1791

  Fly   847 SNSTDKVVN-LMTPLIECLSTPKEL-LYFSKFFK--------EILRDMNGSE--RLI----KILL 895
            .:|:|.:.| |:....:.|:.|.:. ||....|:        |:.:|...|.  .|:    |.:.
 Worm  1792 DDSSDVLYNFLLDNTQDILNAPFDFSLYVKAMFQNWSTSNQLELAKDFQNSSNYNLLNAAQKNIY 1856

  Fly   896 ERG----NDNIHWQRTKFRPMLQAIR 917
            ::|    |.|.:|......|.|:.|:
 Worm  1857 KQGILTVNSNANWMLIYKTPFLEWIQ 1882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	134/490 (27%)
		ERAP1_C	578..897	CDD:463368	72/371 (19%)
T16G12.1	NP_499230.2	M1_APN-Q_like	90..544	CDD:341064
		ERAP1_C	639..931	CDD:463368
		M1_APN-Q_like	1005..1471	CDD:341064	134/489 (27%)
		ERAP1_C	1542..1839	CDD:463368	68/348 (20%)