Protein Alignment CG2111 and mnp-1

DIOPT Version :9

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_497878.1
• Gene: mnp-1 / 175564
• WormBaseID: WBGene00007139
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 769
• Identity: 146/769 - (18%)
• Similarity: 259/769 - (33%)
• Gaps: 204/769 - (26%)

  Fly    27 PKWLVPLSYRVDIVTR-INQP-----YQPFGGT----VVIDLRSERSTKRIVLNAHDLAIGKRRA 81
            |....|:.|.::|..| :.:|     .|.|..|    ..|.|.|        :..|:|. .:.|.
 Worm   172 PSKFQPIHYVLNITIRDVRKPVLEGHMQLFASTKDQVQAISLHS--------VKIHNLE-NRDRI 227

  Fly    82 VTLSDKNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSN---YV 143
            ..::...|.::.||.:.....|..|.::......||            ||.|..||.|::   :|
 Worm   228 HVVNCNTGETICVSRVHQIDDLIHLELAQSISSGVN------------LRVDIDGFISADSGPHV 280

  Fly   144 DHNTTLTQW----LAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHA 204
            .......:|    :..:.|||..||..||.||....::.|.:.|.|.....|::|..:...:..:
 Worm   281 FKQIPTAKWRVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINPNVSTS 345

  Fly   205 SLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDA----------LSQT 259
            .:     :.|.::.|:....::|:..:...|.|.::...|...    .|:.          ..|.
 Worm   346 GI-----SCFEKTVPLIAQQLSFVAFEKTNPLFYNTTTMDGAY----LPEIDMIFNLNAKNFKQY 401

  Fly   260 EFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQ 324
            |:.:..|:.:::........:|...::::|..|  ........|:.....:::.|....|:.:
 Worm   402 EWIHSEVSKVMALMSKWSGFSYPLTRLEIVVAP--VQAGHSALGVITLPAQAIAYQKHTSTHE-- 462

  Fly   325 QGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVL 389
                 .:...|:.||...:|:..  |..:.|.:.| |:          ||...|.  ||:.....
 Worm   463 -----TLIKEVIGQWMEGVVTTE--HTCFEKALIA-YV----------EWKINEE--LQIVKKTR 507

  Fly   390 DYDAHV----NTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYA 450
            ..:...    |.:....||.....|.:..:.:...:...:|..|....|:|..:..:|.....:|
 Worm   508 KMEVSKIRPRNLNETADSVRVLRQIKSQSSNLCSPRFVEVFYTLDETYGQETVIGMIRVIFDKFA 572

  Fly   451 NRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI 515
            ..|||.||:....:...  .||...|..|.:    |.    .|..|::|..  ..|:||..
 Worm   573 FSTATISDWASAAETAT--GGRPEAGALIHQ----WY----RPSSTISRPV--LRAVVSSN---- 621

  Fly   516 TPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEP---TD 577
            :.:|..  .....|.|||          ||           |..:.....|:.||.:|.|   :|
 Worm   622 SVEFNQ--LTEETWTVPL----------EI-----------SGSAGTQLAVISEKKQAIPFVSSD 663

  Fly   578 WILFNVQHTAPFRVNYDLRNWQLLNKTLAD---PNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDM 639
            :::.:....:...|.||...:..|.:...|   |:|           .:..:||     |:...:
 Worm   664 YVVVDAGRKSHAFVVYDADTYLRLIRCFGDSRCPSK-----------EIGGIFS-----DLGAAL 712

  Fly   640 ALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSG 704
            ...||...|::|                 |||       :|:.        ||.:...::...:.
 Worm   713 LANILPKPENQD-----------------VAK-------WKSV--------FKFMAQQNIVEGTA 745

  Fly   705 NMTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKF 758
                       ||      ||..|.||.     .|..:..|::    |||.:.|
 Worm   746 -----------AC------CVEHAIREM-----RKCSYWDIQD----VCTKIDF 773

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	Peptidase_M1	25..421	CDD:279741	77/424 (18%)
		M1_APN_2	33..493	CDD:189008	91/490 (19%)
		ERAP1_C	579..897	CDD:288671	33/183 (18%)
mnp-1	NP_497878.1	Peptidase_M1	172..556	CDD:279741	79/437 (18%)
		GluZincin	<294..>480	CDD:301352	34/203 (17%)
		GluZincin	<547..602	CDD:301352	15/60 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910