Protein Alignment CG2111 and LOC1278754

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_318379.6
• Gene: LOC1278754 / 1278754
• VectorBaseID: AGAMI1_000623
• Length: 880
• Species: Anopheles gambiae
• Alignment Length: 853
• Identity: 220/853 - (25%)
• Similarity: 365/853 - (42%)
• Gaps: 148/853 - (17%)

  Fly     5 YLTILTALFFHLEANKTAVGRLPKWLVPLSYRVDI-VTRINQPYQPFGGTVVIDLRSERSTKRIV 68
            ||.|:..:        ||.|||....:||.|.:.: .|.:......:.|.|.|.:.....|..:|
Mosquito    14 YLVIVPVV--------TANGRLSNNTLPLHYDLHLEATGLGLHDYTYRGNVSIRIAIVSDTNEVV 70

  Fly    69 LNAHDLAIGKR-RAVTLSD-KNGNSV--------PVSSIQMDIKLSRLTVSLKRPLKVNVTYSMR 123
            |  |:  :|.| :::.|.. ::|.::        |.|.: :.|:..|:   |:|.....:|  :.
Mosquito    71 L--HN--VGNRLKSICLRRCRDGEAISHQLLESEPASEL-LRIRTDRI---LRRADDQVIT--LT 125

  Fly   124 VAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYL 188
            :.|.:.|..|..|||.:.|.... .:...:|.|.|:|::||.||||||:|.|:|.|:|.:.....
Mosquito   126 IVFHNTLGEDRMGFYRTQYRGAK-RIPMAVATTHFQPSYARLAFPCFDEPGFKTTFQITIVANGS 189

  Fly   189 YRALSNMPVQRTIRHASLKDYVWTQ-------FVESHPMQTYLVAFMISKFDRPGFTSSERSDCP 246
            :...||.|:...         .|.|       |..:.|||||||.|:|:.|......|.  |...
Mosquito   190 HLVASNAPIATV---------TWLQDGHKAVRFERTPPMQTYLVTFLIANFTSVHTVSP--SGVE 243

  Fly   247 ISTWARPDALSQTEFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEES 311
            |...|.|......:|:......|||..|:....:...:|:|.||:|.|. .:.|||||.|:.|:.
Mosquito   244 IGILAPPKDEKSLQFSLQAATTLLSSLEEYTGQSLGLQKLDHVAIPRFG-NAMENWGLVAYDEQF 307

  Fly   312 LLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALY----LSRFGVHSLRP 372
            |:..::...:...|.|. .:.....:|.|||||..|||..:||...||.|    |.......|.|
Mosquito   308 LVLSAKAHRLQRAQAVL-TIGHETAHQLFGNLVGPAWWSYLWLSEGFATYFELLLGADAYPELLP 371

  Fly   373 -EWDYQERHALQLYLSVLDYDAH-VNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGE 435
             |..:..|| :...|....|:.| :..:.::|:.|:   |...::.|...||..:..|::..:||
Mosquito   372 LEESFAVRH-MHPALMADAYEQHPLTVEPLSANTPE---IETLFDTITYSKAGCILRMINCSIGE 432

  Fly   436 EAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRN 500
            ||:...::.||..:.|...|..|.:....:|..::..     .:.::.:.|:.:||||:|||.|
Mosquito   433 EAFQAGVQNYLEQHRNGIVTPEDLYASFFVQQRKDTP-----TVEQMFRSWVDKPGYPVVTVER- 491

  Fly   501 YDHRTAIVSQQRFF---ITPQ-FRNRWARNPCWWVPLSYTCPSC--QHSEIISFSRWLTCPTSKP 559
            .:.......|||:.   :|.| ..:|      |::|::|...|.  |:....:|  |:
Mosquito   492 LNGSFVRFRQQRYHNQEVTIQDITSR------WFIPITYYTNSSLGQYEYQPAF--WM------- 541

  Fly   560 SSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVD 624
             .:::..|:.:|:....|.::.|.:....:||.||.|.|..:...|.      .:..:.:|:|:|
Mosquito   542 -KETDQELVLQLKMNTQDVLVVNPRQIGFYRVEYDERGWSSIVDNLT------TLPSIMQAKLID 599

  Fly   625 DLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLER 689
            |.|.||.:|.:.|::.|.:|..|....:.|.|:..         :|:.|..||     .|:|...
Mosquito   600 DAFVLARAGLVGYELCLEMLQELATSPDPVPWLIA---------MAEENIGYL-----QRVLQSA 650

  Fly   690 QFKRVISS------DLTSSSGNMTHRPVIIRLACEY--ELPACVSLARREFMKGTPEKGGWMTIR 746
            :|.|.::.      ||..:.|....:...:.:|.::  .|.|....::||           .:||
Mosquito   651 EFDRFLTGFVGEMFDLAGNVGRTLLQSQALDVAYDWWSRLAASFIESKRE-----------SSIR 704

  Fly   747 ER---ETVVCTAVKFGTEGDRDMVESMY-------KRSNFAAEKESLLTALACSR--------NV 793
            .|   .|.|...|:.....|..:.|.::       |:||   |...||.||...|        .:
Mosquito   705 PRACLPTPVQEVVQALVSPDDHVRERLFVRLKCLPKQSN---EPSVLLLALERIRAANLLTPGKL 766

  Fly   794 FALQRVLI 801
            ||:...||
Mosquito   767 FAVLESLI 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	127/477 (27%)
		ERAP1_C	578..897	CDD:463368	59/250 (24%)
LOC1278754	XP_318379.6	None