Protein Alignment CG2111 and LOC1278415

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_318000.5
• Gene: LOC1278415 / 1278415
• VectorBaseID: AGAMI1_009252
• Length: 1020
• Species: Anopheles gambiae
• Alignment Length: 887
• Identity: 246/887 - (27%)
• Similarity: 409/887 - (46%)
• Gaps: 88/887 - (9%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTL-SDKN 88
            |||...:|:.|.:.:.|.|::..:.|.|||.|.|:..::|.::|::...|.:...:..:| :...
Mosquito    64 RLPTTSIPIHYDLHLRTEIHRNERTFTGTVGIQLQVVQATDKLVMHNRGLVMSSAKVSSLPNGVT 128

  Fly    89 GNSVPVSSIQ--MDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQ 151
            |....:..:|  .|.....:|.:....|:.. ||.:.|||...|..::.|||.|:||..|.. .:
Mosquito   129 GAPTLIGDVQYSTDTTFEHITFTSPTILQPG-TYLLEVAFQGRLATNDDGFYVSSYVADNGE-RR 191

  Fly   152 WLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQFVE 216
            :||.||||...||.||||:|:|..:..|.:::.|...|:|:|||| |:|.  ..::..:.|.|.|
Mosquito   192 YLATTQFESTSARMAFPCYDEPGLKATFTVSITHSRSYKAISNMP-QKTF--TDIETDMRTTFFE 253

  Fly   217 SHP-MQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLSFYEDLFNST 280
            ..| |.|||:||::..| :...:.::|      .:.||:||::..||......:|...:|.....
Mosquito   254 KTPAMSTYLLAFVVCDF-QIRLSGAQR------VYVRPNALNEATFALEAGVKILKVLDDHLGIP 311

  Fly   281 Y--RQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNL 343
            |  ...|:|.:|:|||...:.|||||..:.|::||::...|:...:..||..:|....:||||||
Mosquito   312 YDTYMPKLDQIAIPDFAAGAMENWGLVTYREQALLFNPAVSTYRGKTNVATTIAHEYAHQWFGNL 376

  Fly   344 VSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASVPDES 408
            ||..||..|||...||.....:.:....|..:|.|....|:....:..|...:|..:..:.....
Mosquito   377 VSPEWWEYIWLNEGFATLYEFYALDMAYPGQEYWELFNQQVIQYAMGQDGQASTRPMNWNAATPG 441

  Fly   409 HIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRL 473
            .|.|.::.:...|:..:..|:..|:|::.|...|:.||...|.:.|.....:..||..::..|.|
Mosquito   442 EISALFDRVAYDKSGSVLNMMRHVLGDDNWKAGLKAYLTDRALQGAVDEQLYAGLQSAIEGKGVL 506

  Fly   474 GKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQFRNRWARNPCWWVPLSYTCP 538
            ..|:.:.:||:.|..:.|||::.|.|:||....|:||:||:......|    ...|.:|.:|.
Mosquito   507 PNGVTVGQIMRTWTNEAGYPVLNVRRSYDTGDVIISQERFYNDRNVPN----TNIWMIPYNYV-- 565

  Fly   539 SCQHSEIISFS-----RWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVNYDLRNW 598
               |.....|:     :||   .:|.:....||       ...:||:||.|....:|||||.|||
Mosquito   566 ---HQAKADFNEFDDFQWL---ATKAARIETTV-------PANEWIVFNKQQVGYYRVNYDERNW 617

  Fly   599 QLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVATEISF 663
            :|:...|.:  .:..|||:|||||:||.:.||.||.::..:||..:.||.:|.|:..|.|..::.
Mosquito   618 ELITNALHE--NWASIHRLNRAQLIDDAYWLARSGRLDLRVALRFMTYLRNEREYAPWTAANVAL 680

  Fly   664 ERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTHRPVIIRL---ACEYELPACV 725
            ...||..:....|..|..::..|:|..:. :::.|..|....:.|:.::..:   ||......|:
Mosquito   681 TYFNNRLRGTAEYHNFLIFVDALIEDIYS-LLTIDAVSPDDTLLHKYLVQTISTWACSMGYTDCL 744

  Fly   726 ----SLARREFMKGT-----PEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMYKRSNFAAEKE 781
                :|.:.| ..||     |:..        ....|..::...|.:...:......|...||:.
Mosquito   745 MKTAALLKAE-ASGTGPAVHPDIA--------SVTYCYGMRSALESEFQYLYRKMMNSKNLAERT 800

  Fly   782 SLLTALACSRNVFALQRVLIWTFES-SGV----RKQNARRTFKAVVSNS-----------MGYRL 830
            .|:.:|.||.|...|:..|.....| :||    |....||..:|:.|..           |...|
Mosquito   801 MLIDSLGCSNNKEFLKAFLTTALGSGTGVEINYRADERRRVVQAIYSGGRTGVDALIEFLMDPAL 865

  Fly   831 AKKYVSV----NMQNIRNYCSNSTDKV--VNLMTPLIECLST 866
            ..::||.    .:.:..:..::.|:.|  :|.:..||..|.:
Mosquito   866 VNEFVSTLSTSTLNSALSAIASRTNNVEEMNKLNALITALGS 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	134/459 (29%)
		ERAP1_C	578..897	CDD:463368	84/323 (26%)
LOC1278415	XP_318000.5	None