Protein Alignment CG2111 and LOC1275101

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_314331.5
• Gene: LOC1275101 / 1275101
• VectorBaseID: AGAMI1_000111
• Length: 915
• Species: Anopheles gambiae
• Alignment Length: 962
• Identity: 248/962 - (25%)
• Similarity: 408/962 - (42%)
• Gaps: 162/962 - (16%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVT---LSD 86
            |||...||..|.:.:.|.|::....:.|.|.|.:....:|.:|||::      .|..:|   |.:
Mosquito    40 RLPNTTVPTHYTLRLDTDIHREIFDYTGNVQIRINVLEATDQIVLHS------SRSEITHVQLRN 98

  Fly    87 KNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNV-TYSMRVAFT-SVLRNDNTGFYSSNYVDHNTTL 149
            ..|.||||.:.:.|.....|.|::...|:.|. ||::.:.|| |:.|||..|||.|:|.|.| .:
Mosquito    99 GVGLSVPVKNFEFDEDKEFLVVNVGTTLQPNTGTYTLEIDFTNSIARNDQAGFYRSSYDDEN-GV 162

  Fly   150 TQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKD--YVWT 212
            .::|..||||...||.:|||:|:|..:|.:.|.:.....|.|.||.|    :|...|.:  ...:
Mosquito   163 RRYLGLTQFESVDARTSFPCYDEPGIKTTYDILIVCGIDYHARSNAP----LRGIQLLEGGKKLS 223

  Fly   213 QFVESHPMQTYLVAFMIS--KFDRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLSFYED 275
            .|..:..|||||||:::|  |::|...|..:.:   |::|::|.::....::.......:...|:
Mosquito   224 TFATTPRMQTYLVAWLVSDFKYEREVLTDPQLA---IASWSKPSSVHLLSYSVDASKRFMRAMEE 285

  Fly   276 LFNSTYRQKKIDLVAL--PDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQ---GVARAVAMMV 335
            .|:..|...|||.||:  .|:...:.|||||..:.|.::.|..:    |.:|   ||...|....
Mosquito   286 YFDQLYSMSKIDNVAIKDEDYAAGAMENWGLVTYKESAISYGPE----DGEQRQVGVVTIVGHEF 346

  Fly   336 VNQWFGNLVSVAWWHEIWLKNVFA-LYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDL 399
            .:|:||||::..||..:||...|| ||....|..| .||...:||.....:.:.|..|..:....
Mosquito   347 THQFFGNLLAPKWWSYLWLNEGFARLYQYYLGAIS-HPELQLRERFVTGPFQTALRADNSLTVRP 410

  Fly   400 VTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANR-TATSSDFWDLL 463
            :|........|...::.|...|:|.:..|::..:||..:...||.||.....| ....|:.:|.|
Mosquito   411 MTYYTETRPSISRLFDSIAYDKSACVLRMMNYALGERTFQKGLRYYLQQNKERGVVEESNLFDSL 475

  Fly   464 QLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI-TP---QFRNRWA 524
            :.....:..|...|:|..|...|..|||.|||.|.|  |....:.:|:|:.. ||   .|.|
Mosquito   476 EQAAKEDAVLPISLSIHEIFGSWSHQPGVPLVKVRR--DGNEYLFTQERYIANTPPEEPFEN--- 535

  Fly   525 RNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPF 589
               .||:|:|::.||....|.:. :.|:     .|:.......:|.::.|.   :.||...|..:
Mosquito   536 ---SWWIPISFSTPSNNAFEKLP-AFWM-----PPNVSEVAYTIETVQDEV---VSFNPHSTGYY 588

  Fly   590 RVNYD---LRNWQLLNKTLADPNKFRLIHRVN----------RAQLVDDLFSLAWSGDIEYDMAL 641
            ||.|:   ||               .||.|:|          ||:|:||..::|.|....||:.|
Mosquito   589 RVEYEESMLR---------------ELIERINKDHTGFEPATRARLIDDTLNIAQSRGGNYDVVL 638

  Fly   642 GILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDL------- 699
            .:|.||:.|.::|.|.....:...:.::.::|       ..:..||||..:::.|..|
Mosquito   639 QLLNYLQRETDYVPWAVAYENLRHMQSMLRTN-------EAVSQLLERFIEKIASPLLERYGVDH 696

  Fly   700 ----TSSSGNMTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKFGT 760
                ::|.|.:  |.:.|.|||... .:|...|:........:|...|   |...::|..::...
Mosquito   697 RTGESASVGEL--RTIAIDLACSGS-QSCKDDAQSAVRSLASKKHYTM---EDNALLCHGLQQSN 755

  Fly   761 EGDRDMVESMY------KRSNFAAEKESLLTALAC--------------------SRNVFALQRV 799
            ...|..:::.:      |..:..:.|:.||.:|:|                    |....||.|:
Mosquito   756 AEQRKSLQAQFSQVLSDKNLDNPSAKQFLLQSLSCLGGDMTKVQSFAKYLLALSESDRTKALHRL 820

  Fly   800 LIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECL 864
            |:..........|:.:.......|||:.|:...|.:.    .|..|.::..|  |.|::.:...
Mosquito   821 LVELNVPLAEIVQSLQSELSQRRSNSVYYKHGPKLIF----EIARYVTDPAD--VQLLSSVASS- 878

  Fly   865 STPKELLYFSKFFKEILRDMNGSERLIKILLERGNDNIHWQRTKFRPMLQAI 916
                   |.|....||.:.:|.              |::|......|:..|:
Mosquito   879 -------YDSWVASEIEQQVNA--------------NLNWVEQNVEPLKNAL 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	136/469 (29%)
		ERAP1_C	578..897	CDD:463368	76/368 (21%)
LOC1275101	XP_314331.5	None