Protein Alignment CG2111 and LOC1274368

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_061505691.1
• Gene: LOC1274368 / 1274368
• VectorBaseID: AGAMI1_004163
• Length: 818
• Species: Anopheles gambiae
• Alignment Length: 810
• Identity: 217/810 - (26%)
• Similarity: 368/810 - (45%)
• Gaps: 96/810 - (11%)

  Fly   133 DNTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPV 197
            ||..:|..|       |.::||.|.|...:||..|||:|:|..:..|.:.:.|...:.|||||||
Mosquito    15 DNVVYYFCN-------LLRYLATTFFAATYARTVFPCYDEPGHKARFNVKIRHRSHHTALSNMPV 72

  Fly   198 QRTIRHASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTEFA 262
               ||...:..|..|.|..:..|.||||||::|:..    |.|...:. ...:|..:.::.|.:|
Mosquito    73 ---IRSTMIDGYSETTFDTTPLMSTYLVAFVVSEMK----TLSSIGEL-FRVYAPENKVNYTVYA 129

  Fly   263 NMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLY-DSQRSSIDDQQG 326
            :......:...|:.|....:.:|||||.:|||...:.||||:..|.|:.|:| |.::::...:|.
Mosquito   130 HDFAVRAVRALENHFGRQNQMRKIDLVGIPDFAMGAMENWGMITFREDYLIYQDEEKTTALAKQK 194

  Fly   327 VARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDY 391
            :|..:...:|:.||||.|:..||..:||...||.:...:....|.|.|...::..|......|..
Mosquito   195 IASVITHELVHMWFGNEVTPEWWTYVWLNEGFANFFEYYITSQLEPAWRLWDQFILDNVHWALSK 259

  Fly   392 DAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTAL------RRYLVVYA 450
            |:|.:...:.....|.:.:...|:.:...|:|.:..|:..|:|.:.:..|:      |.||....
Mosquito   260 DSHSSVRPMNYYATDPAVLNGLYDYVVYEKSASVIRMIQNVIGFDTFQQAINDYLRSRSYLTTRP 324

  Fly   451 NRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI 515
            ....||.:.:..:.|..          ::..|.:.|...||||:|||:.:...||...||:||::
Mosquito   325 QYLYTSIEKFRTVDLPA----------SVEVIFESWANTPGYPVVTVSIDRTKRTLTASQKRFWM 379

  Fly   516 TPQFRNRWARNPCWWVPLSY--TCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDW 578
             |...:...:|..:::|::|  ..|:....|..:.:.|||     |...:.||.||    ...:|
Mosquito   380 -PNELDTPPQNMLFYIPVNYGSNVPTSTDFEDTTPTFWLT-----PQDPTATVSLE----AGVEW 434

  Fly   579 ILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGI 643
            ::.|.|.|..:|||||..:|..|.:.|........:..:||||||||:.:||.:|::.||:||.:
Mosquito   435 VVVNKQQTGYYRVNYDDESWHKLIEVLNSDQFEDQLPVINRAQLVDDVANLARAGEVGYDVALSL 499

  Fly   644 LGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTH 708
            :.|||.|.|::.|.....:.:.::.:..|:..|..|:.|:.:|....|..:...| |.|..|..|
Mosquito   500 MQYLERETEYIPWATAYNALQHLDRMFSSHKEYNRFENYVGILTSHVFNEMNLFD-TESHLNRLH 563

  Fly   709 RPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERETVVCTAVKFG--TEGDRDMVESMY 771
            |...:.|||.:.:.||:..|.:...:...|:...:....:..|.|...|:.  .|||..:  .::
Mosquito   564 RDKSVYLACYFGVEACLDAATKIIEEALAEETLNIPKELQNAVFCALHKYDLLVEGDYGL--EIF 626

  Fly   772 KRSNFAAEK-----ESLLTALACSRNV----FALQRVLIWTFESSGVRKQNA---RRTFKAVVSN 824
            ::...|.::     :..:.||.||||:    |.||.:.|         .:.|   ..:.|..:.|
Mosquito   627 QKYWLATDQYQPLMDKFINALGCSRNLAMNEFYLQMIEI---------NETALPITVSMKNNILN 682

  Fly   825 SM------GYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILR- 882
            ||      ....|.:|||.....:.|..::....:.|   .|.:.:::|:|.    ...||::.
Mosquito   683 SMIKGGPATRSAAFRYVSARFDTVSNMLNHELSAMFN---ALGDSVNSPREY----DMLKELIHT 740

  Fly   883 --------DMNGSERLIKILLERGNDNIHW 904
                    .|..:.|    .|.:..:|:||
Mosquito   741 HQTSLNPSSMQAATR----ALAQAEENLHW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	98/360 (27%)
		ERAP1_C	578..897	CDD:463368	88/347 (25%)
LOC1274368	XP_061505691.1	None