Protein Alignment CG2111 and LOC1272139

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_311017.5
• Gene: LOC1272139 / 1272139
• VectorBaseID: AGAMI1_006784
• Length: 953
• Species: Anopheles gambiae
• Alignment Length: 935
• Identity: 221/935 - (23%)
• Similarity: 389/935 - (41%)
• Gaps: 110/935 - (11%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNA-HDLAIGKRRAVTL---S 85
            :||..|||..|.:.:...:::..  |.|.|.|.|...::|.:|.|:| |||.:.:.....:   .
Mosquito    46 KLPTDLVPSGYSLHLHPVLDRSI--FSGRVNITLLCAKATNQINLHAHHDLTVDELELEVVRIGG 108

  Fly    86 DKNGNSVPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLT 150
            .:.|..||:..:....|...|.:.....|.....|.:|:.|...:..:..|.:...|....:|..
Mosquito   109 AEGGTKVPIRRVDRVPKKPLLVIYFHDALTAGAAYEVRLRFVGNIWENVEGIFEGKYKQQQSTGP 173

  Fly   151 QWLAATQ----------------FEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQR 199
            ...|.|:                |.|:|||..|||||:|.::.||.:::..|..:..|.|..::|
Mosquito   174 SEPAGTESEGVTEPEEHSFIGTYFRPHHARRVFPCFDEPSYKVPFNVSIVRPRTHHVLFNTALER 238

  Fly   200 TIRHASLKDYVWTQFVESHPMQTYLVAFMISKFDR--PGFT---SSERSDCPISTWARPDALSQT 259
            |:.....| :|...|.::.||.|:...|::|...:  |..:   ..||....|..|||.|.....
Mosquito   239 TVETGDGK-HVIDVFKQTAPMSTFTFGFLVSDLQQVTPSLSDEKEDERLKPTIRVWARRDFQKNV 302

  Fly   260 EFANMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTF-KSKENWGLPAFAEESLL---YDSQRSS 320
            ......|...|...::.:......:|:|:||||.|:: |..:||||..|.|..|:   |:
Mosquito   303 ADVQQRVKLALRKLQEYWGVPLPLEKLDVVALPGFSYVKPADNWGLIVFKESELMRGYYN----- 362

  Fly   321 IDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLY 385
                      :|..:|.||.|:.::..||.:..:....|.:||......:....:::.::.:.:.
Mosquito   363 ----------LAQELVYQWLGSWITPHWWSDAHVNKAIAGFLSADTAIKIDGGDEFEGKYPMTIL 417

  Fly   386 LSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYA 450
            .|:. |:       .:...| .|.|.|...|....|..::..||:..:|||.:...|:|::....
Mosquito   418 YSIY-YE-------FSKRYP-HSRITAMKQETTCSKTELVLRMLNYTLGEETFRRGLQRFIQHRE 473

  Fly   451 NRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI 515
            .:|....|.|:.|..|...:.||.:.:.:..::..|:.:...|:|.|.|:|.:|||.|:|:.:
Mosquito   474 YKTFYGEDVWEALTKQAHLDQRLCESVTVNDVVNSWITKDRIPMVRVVRSYANRTATVTQRLY-- 536

  Fly   516 TPQFRNRWARNP-----CWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEP 575
               .|.|....|     .||:||........:...:|..||:        .:...|.|::|.. |
Mosquito   537 ---LRERPHDVPEQDKMLWWIPLVVVRQDRLNFGNVSTIRWM--------KQVREVTLDELPG-P 589

  Fly   576 TDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMA 640
            .::|:.|.:...||.||||.|||.||...|.......:|....||:|:.|.::||::||:.:..|
Mosquito   590 DEFIIVNPEEIGPFPVNYDERNWNLLATFLQKEESRTMIPVYTRAKLLHDAWNLAYAGDLSFGTA 654

  Fly   641 LGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSS--- 702
            ..:..::::|...:||.......:.|......:..:..|:.|:|.||...::.::.:...|.
Mosquito   655 FNMTLFMKYERNHLVWNPVFTLIDHIGRHIDMSAVHKKFEMYVRTLLTPLYEELVGNQQESEEMW 719

  Fly   703 SGNMTHRPVIIRLACEYELPACVSLARREFMKGTPEKGGWMTIRERET-------VVCTAVKFGT 760
            ..|:  |.:.....|......|:..|:|.|.|       ||...:.:.       .:|...|:||
Mosquito   720 KANL--RSLAKNFLCRAGYKPCIEEAQRAFKK-------WMDSPDPDAGNPVANQFICPVFKWGT 775

  Fly   761 E-----GDRDMVESMYKRSNFAAEKESLLTALA-CSRNVFALQRVL-IWTFESSGVRKQN-ARRT 817
            .     |.:.::.  :..|...:|:..||..|| |....|.:.|:| |...|.:|....| ....
Mosquito   776 REEWEFGLQRVIN--FPESRVKSERTYLLKTLAGCPSQPFKIDRLLNIMVLEDNGNFTDNDISLI 838

  Fly   818 FKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNST---DKVVNLMTPLIECLSTPKELLYFSKFFKE 879
            ||.:...|.||.....::..|...|:....:..   |.::|..|.|   .:|.:.....|:.:.:
Mosquito   839 FKMLSGGSSGYSTLFNFLKNNWDAIKLRFKDRESLWDNMINSATGL---FTTQEGYDMVSQLYVQ 900

  Fly   880 ILRDMNGSERLIKILLERGNDNIHW 904
            ...:...:|.:|:..|:...:...|
Mosquito   901 HQGEFGTAEHIIEKSLKNIKEETKW 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	111/482 (23%)
		ERAP1_C	578..897	CDD:463368	79/339 (23%)
LOC1272139	XP_311017.5	None