Protein Alignment CG2111 and LOC1270378

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_309093.5
• Gene: LOC1270378 / 1270378
• VectorBaseID: AGAMI1_011814
• Length: 1133
• Species: Anopheles gambiae
• Alignment Length: 1137
• Identity: 226/1137 - (19%)
• Similarity: 383/1137 - (33%)
• Gaps: 334/1137 - (29%)

  Fly     8 ILTALFFHLEANKT---AVGRLPKWLVPLSYRVDIVTRINQPYQPFG------------------ 51
            :.|||.......:|   ..|::|...||..|      ..::|:||..
Mosquito    73 LATALVIAYAGPQTVCPCAGKIPPGYVPDGY------NSSEPFQPIATNGQPFPWLLPTLPNNVK 131

  Fly    52 ------------------GTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNGNSVPVSSIQ 98
                              |.|.|:|..|:.|..:||:|.||.|.::   .|....|.::.:..:.
Mosquito   132 PNRYILTIHPNLTTLDVKGQVSIELYVEKETNFVVLHAQDLNITEK---ALVGPKGFALKILRML 193

  Fly    99 MDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQWLAATQFEPNHA 163
            ......:|.:..:..|:....|::.:.:.|.:..|.        .:.:..:.:.||||..:|...
Mosquito   194 EYTPRQQLYIETREKLRKKANYTLSIRWHSKMILDQ--------FEGDFDMKKTLAATVLKPGST 250

  Fly   164 REAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRT------IRHASLKDYVWTQFVESHPMQT 222
            |:||||||:|..|..|||:|.....:..|||..||.|      :....|:|    .|.|:.|:..
Mosquito   251 RKAFPCFDEPHLRAAFKISLFRDRFHIGLSNSIVQDTDDVGFYMGTGLLRD----DFAETPPLPP 311

  Fly   223 YLVAFMISKFDRP----------------GFTSSERSDCPIST------WARPDALSQTE---FA 262
            ..|:::||.|.|.                |.:::.....|.||      .:.|..:::||   |.
Mosquito   312 DSVSWVISDFRRELLEPSAKYQKVNASGNGASAAGAGKVPPSTAGAGNGKSTPSKVTKTEKKPFR 376

  Fly   263 NMV-------------------------------------------------------------V 266
            |:.                                                             .
Mosquito   377 NLTAVLLSKNLFKLTNTAPTKEPTQIENDVTISAAESGPAVAKSNGTVLPEHDALWNGDTALIRT 441

  Fly   267 APLLSFY-----------------------EDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFA 308
            ||..|||                       :...:..|...|:|.||||........:.|:....
Mosquito   442 APAYSFYAPETHIAKGTFILHTSRDILEYLQQWLSVAYPLSKLDFVALPSLLDDLSSSLGIIVCR 506

  Fly   309 EESLLYDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPE 373
            ...|...:..||.:....|.: ::..:|.|:||.|:|...|...||......|||||.:.:::|.
Mosquito   507 TSFLNEPTAISSKEYHMSVVK-ISEGIVKQYFGGLISPKVWKHKWLWEGLIRYLSRFLLATIQPL 570

  Fly   374 WDYQERHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAW 438
            |..:|...:......||.||....:.::|...|.......|.:    |:|.|..||...:||..:
Mosquito   571 WPMKELFLIDTLTKALDIDALQGWESISAGASDSGDNDPFYVD----KSAALLSMLQSAIGERNF 631

  Fly   439 LTALRRYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDH 503
            ...|.::|..|..:||..||.|.:...||: |.:.     :..:|..|.....:||:.||.|
Mosquito   632 RQCLGKFLKTYQFQTAEPSDLWAICAKQVN-NSKY-----VREMMNQWTNTAAFPLLNVTMN--- 687

  Fly   504 RTAIVSQQRFFITPQF-------------RNRWARNPC--------------------WWVPLSY 535
            .|::..:|..|...::             .....|:..                    |..|:.|
Mosquito   688 GTSLTVRQTGFRPAEYLAIYDEPMEEIEREGEQGRSTTTTPAPVDATGKSGSGEAGTRWVFPIHY 752

  Fly   536 ---------TCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRV 591
                     |....:|.|..|...||        :.|..::.....|:   ||..|...|..:||
Mosquito   753 ITDVLNTNETAAEAEHKEQQSLIIWL--------NSSEVIITLNHTAQ---WIKLNHGQTGYYRV 806

  Fly   592 NYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVW 656
            .||..||..|.:.:...|  .:....:|..||.|:|:|..:..|....|:.::.|...|.|:...
Mosquito   807 LYDEANWAKLVEQMQINN--AVFSTQDRVGLVSDIFTLCHANLIPCHAAMELISYFPKEKEWGPI 869

  Fly   657 VATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTHRPVIIRLACEYEL 721
            |......|:...:.|.:..||:...|:|..|.:.. :|:..|.|........|||::..|..:|.
Mosquito   870 VLGTSHLEKWRKILKYSECYLVLAEYVRQNLAKSI-QVLGWDDTGEDETKLLRPVLMLSAALWEE 933

  Fly   722 PACVSLARREFMKG--------------------------TPEKGGW-------MTIRERETVVC 753
            ...:     :|.||                          :.|...|       ||:|.
Mosquito   934 SETI-----KFAKGLVTNFTTHSIPIPPNLRSVAYIGSVLSGEFQYWQFCWDRYMTVRR------ 987

  Fly   754 TAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVL-----IWTFESSGVRKQN 813
                              ::|:...|:..||.||..:::.:...|:|     :..||...|
Mosquito   988 ------------------EKSSVLEERMELLRALGVTKDAWLQNRLLSHVITLPVFEIVQV---- 1030

  Fly   814 ARRTFKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFK 878
                .:|:.....|..:|.:::.....:.::.....|.:...:::.:.:..||        ||..
Mosquito  1031 ----LEAIAGTPTGGAMACRFLQAKWFDFQSKLGRGTVQFARVISAITQYGST--------KFDY 1083

  Fly   879 EILRDM------NGSERLIKILLERGNDNIHW 904
            :.|:.:      ....:|:.:.|.....|:.|
Mosquito  1084 DELKSLVERFGDGPGLKLLNMTLSTVAANVEW 1115

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	126/604 (21%)
		ERAP1_C	578..897	CDD:463368	69/362 (19%)
LOC1270378	XP_309093.5	None