Protein Alignment CG2111 and LOC11175889

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_003436573.2
• Gene: LOC11175889 / 11175889
• VectorBaseID: AGAMI1_012506
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 923
• Identity: 241/923 - (26%)
• Similarity: 405/923 - (43%)
• Gaps: 118/923 - (12%)

  Fly    29 WLVPLSYRVDIVTRI----NQPYQPFGGTVVIDLRSER-STKRIVLNAHDLAIGKRRAVTLSDKN 88
            |  |..|.::|...:    |:....|.|:..|.:.::: :..:|.|:...:.|   .|.:::.|:
Mosquito    52 W--PTHYDIEIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKLHMARMDI---TAWSVTRKS 111

  Fly    89 GNS-VPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQW 152
            .|: :|......|.:...||:.|...|:.||.|.:...:...:.:|..|||.|.|.:....:  |
Mosquito   112 DNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMDDDMHGFYRSYYWEDGVKV--W 174

  Fly   153 LAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSN--------MPVQRTIRHASLKDY 209
            :.:|||:..|||.||||||:|.|:..|::.:.|...|...||        ..|.||:
Mosquito   175 MGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKTQYNVYSNTAIVGTAVAEVGRTL-------- 231

  Fly   210 VWTQFVESHPMQTYLVAFMISKF---DRPGFTSSERSDCPISTWARPDALSQTEFANMVVAPLLS 271
              |.|..:..|.:||:||:::.:   ||.|          :...|||.|.:||:::..|...||.
Mosquito   232 --TTFGVTPSMSSYLIAFIVAPYQINDRDG----------MGILARPQAQNQTQYSLDVGIKLLK 284

  Fly   272 FYEDLFNSTYR----QKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVA 332
            ..|:..:..|.    ..::.:.|:|||:..:.|||||..:.|.::||.|..|:...|..:|..::
Mosquito   285 ALEEWIDYPYASVAGMTRMYMAAVPDFSAGAMENWGLLTYRETNILYRSDDSTSMQQHRIAAVIS 349

  Fly   333 MMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNT 397
            ..:.:||||:||:..||...||...||.|...:|...:..||:...:..::....|:..|:..:|
Mosquito   350 HEIAHQWFGDLVTCEWWDVTWLNEGFARYYQYYGTALVETEWNLDHQFVVEQLQGVMQMDSLRST 414

  Fly   398 DLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDL 462
            ..:|..|..::.....::.|...|.||:..|:...:..|.:.||||.|:...|.:|....|.:..
Mosquito   415 HPMTHPVYTQAQASGIFDNISYNKGAVMLRMMEHYLTTETFKTALRAYIKDRAFKTTRPEDLFSA 479

  Fly   463 LQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAI-VSQQRFFITPQFRNRWARN 526
            |. :.|.|.|        ..|:.|..|.||||||||   .|.|.. ::|:||.:.....|   ..
Mosquito   480 LN-RYDPNAR--------SYMEPWTIQSGYPLVTVT---SHDTGFTITQKRFLVNEPDHN---EQ 529

  Fly   527 PCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSN-TVLLEKLEAEPTDWILFNVQHTAPFR 590
            ..|.:|:::...:.:.|            .::|:..:. |..:....|...::.:.|.|....:|
Mosquito   530 IAWPLPITFATKASEFS------------ITRPAFYTGMTFEIPMQGASDVEYFILNNQQVGYYR 582

  Fly   591 VNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVV 655
            ||||...|..::|.|.... |..||.:||||:|||||:||....:.|..||.||.||:.|.|:..
Mosquito   583 VNYDAILWGKISKALHSEG-FGGIHVLNRAQIVDDLFNLARGDVVPYGTALEILEYLKEETEYAP 646

  Fly   656 WVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNM-TH-RPVIIRLACE 718
            |:|.......::....::...| |..::..:..:.:..|.....|::...: |: |..:::.||.
Mosquito   647 WLAAVNGLTTLSRRIHADDEKL-FAAHILDIFSKAYDIVKFQAPTATERRIFTYMRQNVLQWACN 710

  Fly   719 YELPACVSLARREF--------MKGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMYKRSN 775
            |....|...|..||        :|..|:.        |:.|.|..::.|:..:.:.:.:.|..:|
Mosquito   711 YGHEECSKAAVAEFHRYHQNPSVKVHPDL--------RQVVYCEGIRKGSTEEFEFLWNQYLTTN 767

  Fly   776 FAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVSNSMGYRLAKKYVSVNMQ 840
            .|.|:..:|..|.|..:...:..:|. ...|..||.|:....|..|::|........:|:   .|
Mosquito   768 VATEQILILQGLGCVSSSELITDMLN-GIASPHVRSQDKNNAFTYVINNPYTLPHVSRYL---QQ 828

  Fly   841 NIRNYCSN--STDKVVNLMTPLIECLSTPKELLYFSKFF---KEILRDMNGSERLIKILLE---- 896
            |..|:.::  |...|.:....::..|.:..|....|.|.   |.||.  ..:...||..||
Mosquito   829 NHANWAASHGSYTNVASAFNNVLARLKSDSERDAISAFIESNKNILG--QAAYDSIKSGLEDYET 891

  Fly   897 ------RGNDNIH 903
                  |..|.||
Mosquito   892 NKQFTLRNRDEIH 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	127/474 (27%)
		ERAP1_C	578..897	CDD:463368	86/343 (25%)
LOC11175889	XP_003436573.2	None