Protein Alignment CG2111 and LOC11175602

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_003436572.2
• Gene: LOC11175602 / 11175602
• VectorBaseID: AGAMI1_012959
• Length: 935
• Species: Anopheles gambiae
• Alignment Length: 944
• Identity: 245/944 - (25%)
• Similarity: 422/944 - (44%)
• Gaps: 123/944 - (13%)

  Fly    13 FFHLEANKTAVG---RLPKWLVPLSYRVDIVTRI----NQPYQPFGGTVVIDLRSER-STKRIVL 69
            :|.:||...|..   ||...:.|..|.::|...:    |:....|.|:..|.:.::: :..:|.|
Mosquito    31 YFLVEAEPRAQPEDYRLNDDVWPTHYDIEIKPYLEQEGNKAQFTFDGSAKITVSTQKQNVMQIKL 95

  Fly    70 NAHDLAIGKRRAVTLSDKNGNS-VPVSSIQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRND 133
            :...:.|   .|.:::.|:.|: :|......|.:...||:.|...|:.||.|.:...:...:.:|
Mosquito    96 HMARMDI---TAWSVTRKSDNTIIPTLPQTYDQETQILTLPLSSALQANVEYVLSFTYVGNMDDD 157

  Fly   134 NTGFYSSNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSN---- 194
            ..|||.|.|.:....:  |:.:|||:..|||.||||||:|.|:..|::.:.|...|...||
Mosquito   158 MHGFYRSYYWEDGVKV--WMGSTQFQQTHARRAFPCFDEPRFKATFQLKINHKTQYNVYSNTAIV 220

  Fly   195 ----MPVQRTIRHASLKDYVWTQFVESHPMQTYLVAFMISKF---DRPGFTSSERSDCPISTWAR 252
                ..|.||:          |.|..:..|.:||:||:::.:   ||.|          :...||
Mosquito   221 GTAVAEVGRTL----------TTFGVTPSMSSYLIAFIVAPYQINDRDG----------MGILAR 265

  Fly   253 PDALSQTEFANMVVAPLLSFYEDLFNSTY----RQKKIDLVALPDFTFKSKENWGLPAFAEESLL 313
            |.|.:||:::..|...||...::..:..|    ...::.:.|:|||:..:.|||||..:.|.::|
Mosquito   266 PQAQNQTQYSLDVGIKLLKALDEWLDYPYASMPAMTRMYMAAVPDFSAGAMENWGLLTYREANIL 330

  Fly   314 YDSQRSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQE 378
            |.|..|:...||.:|..::..:.:||||:||:..||...||...||.|...:....:...||:::
Mosquito   331 YRSDDSTSMQQQRIATVISHEIAHQWFGDLVTCEWWDVAWLNEGFARYYEYYATALVETNWDFED 395

  Fly   379 RHALQLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALR 443
            :..:....||:..|:..:|..:|..|..::...|.::.|...|.||:..|:...:..|.:.||||
Mosquito   396 QFVVAQLQSVMQMDSLRSTHPMTHPVYTQAESSAIFDSITYNKGAVVLRMMEHYLTTETFKTALR 460

  Fly   444 RYLVVYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAI- 507
            .|:...|.:|....|.:..|. :.|.|.|        ..|:.|..||||||||||   .|.|..
Mosquito   461 AYIKDRAFKTTRPEDLFSALN-RYDPNAR--------SYMEPWTVQPGYPLVTVT---SHDTGFT 513

  Fly   508 VSQQRFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSN-TVLLEKL 571
            |:|:||.:.....|   ....|.:|:::...:.:.|            |::|:..:. |..:...
Mosquito   514 VTQKRFLVNEPDHN---EQTAWPLPITFATKASEFS------------TTRPAFYTGMTFEIPMQ 563

  Fly   572 EAEPTDWILFNVQHTAPFRVNYDLRNWQLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIE 636
            .|...::.:.|.|....:|||||...|..::|.|.... |..||.:||||:|||||:||....:.
Mosquito   564 GASDVEYFILNNQQVGYYRVNYDAILWGKISKALHSEG-FGGIHVLNRAQIVDDLFNLARGDVVP 627

  Fly   637 YDMALGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTS 701
            |..||.||.||:.|.|:..|:|.......::....::...| |..::..:..:.:..|.....|:
Mosquito   628 YGTALEILEYLKEETEYAPWLAAVNGLTTLSRRIHADDEKL-FAAHILDIFSKAYDIVKFQAPTA 691

  Fly   702 SSGNM-TH-RPVIIRLACEYELPACVSLARREF--------MKGTPEKGGWMTIRERETVVCTAV 756
            :...: |: |..:::.||.|....|...|..||        :|..|:.        |:.|.|..:
Mosquito   692 TERRIFTYMRQNVLQWACNYGHEECSKAAVAEFHRYHQNPSVKIHPDL--------RQVVYCEGI 748

  Fly   757 KFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAV 821
            :.|:..:.:.:.:.|..:|.|.|:..:|..|.|:.: ..|..:::....|..||.|:....|..|
Mosquito   749 RKGSMEEFEFLWNQYLTTNMATEQLLILQGLGCASS-SELITIMLDAITSPHVRSQDKSNAFTYV 812

  Fly   822 VSNSMGYRLAKKYVSVN----------MQNIRNYCSN-----STDKVVNLMTPLIECLSTPKELL 871
            ::|........:|:..|          ..|:.:..:|     .:|...::::..||   :.|.:|
Mosquito   813 INNLYTLPHVSRYLQQNHAIWAASHGSYANVASAFNNVLARLKSDSERDVISAFIE---SNKNIL 874

  Fly   872 YFSKF--FKEILRDMNGSERLIKILLERGNDNIH 903
            ..:.:  .|..|.|...:::...    |..|.||
Mosquito   875 GQAAYDSIKSGLEDYETNKQFTL----RNRDEIH 904

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	128/474 (27%)
		ERAP1_C	578..897	CDD:463368	81/345 (23%)
LOC11175602	XP_003436572.2	None