Protein Alignment CG2111 and LOC11175588

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_061502291.1
• Gene: LOC11175588 / 11175588
• VectorBaseID: AGAMI1_013558
• Length: 958
• Species: Anopheles gambiae
• Alignment Length: 895
• Identity: 229/895 - (25%)
• Similarity: 389/895 - (43%)
• Gaps: 80/895 - (8%)

  Fly    26 LPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNGN 90
            ||...||..|.:.:.|.|:...:.|.....|.|.....|..||::..:|.|.......::...||
Mosquito    71 LPNTTVPTHYSISLRTDIHNDVRTFSAITRIYLTVLAPTDLIVMHVQELNIASVALYRIASTGGN 135

  Fly    91 SVPVSS--IQMDIKLSRLTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDHNTTLTQW- 152
            .:.:.|  ..:||....:|......|.:. .|::.||:|..:||..:|:..|.|   .....:|
Mosquito   136 EIWIDSPTYMIDIVREHVTFRTAGMLPLG-NYALEVAYTGSMRNYQSGYLVSRY---RNEANEWR 196

  Fly   153 -LAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKDYVWTQFVE 216
             :..|.|:...||..|||:|:|..:..|.:.:.|...|.|::|||:..|....:.::|:.::|..
Mosquito   197 SVGTTHFQATLARRVFPCYDEPALKATFDLKITHHRTYTAIANMPLAGTDIDPNDREYLVSRFER 261

  Fly   217 SHPMQTYLVAFMISKFD--RPGFTSSERSDCPISTWARPDALSQTEFANMVVAPL-----LSFYE 274
            :..|.|||:||.::.|.  |.|     :.:..:.:.|:.||:......:.::..|     ||:|:
Mosquito   262 TPLMSTYLLAFAVTDFKTLRNG-----QHEIVVRSNAQDDAMYALTVGSTILERLGSYLELSYYD 321

  Fly   275 DLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMMVVNQW 339
            .:       .|:..:|:||....:.|||||..:.|.||||....::..:::.|...:|....:||
Mosquito   322 YM-------PKMTSIAVPDRGTGAMENWGLVTYGEPSLLYSPAVNTYRNRKRVTTVIAHEYAHQW 379

  Fly   340 FGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYDAHVNTDLVTASV 404
            ||:|||...|..|||...||............|..:|.|..::::.......||:.....:....
Mosquito   380 FGDLVSPRSWDFIWLSEGFATLYEYLATRLAEPGDEYWELFSVEVVQRAFLQDANEQIRPINWQA 444

  Fly   405 PDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLLQLQVDR 469
            ..::.:.:.::.|..:||..:..|...|:||..|...|.:||.......||..:....||..|:.
Mosquito   445 ATQAEVSSLFDIIAYQKAGSVLNMFRNVLGESEWRQGLTQYLTDRGYDAATEENLALHLQRAVEG 509

  Fly   470 NGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFF---ITPQFRNRWARNPCWWV 531
            ...|....|:..::..|...||:|::.|.|.|.....|:||:||.   :.|       ....|.:
Mosquito   510 KDILPPTANVRDLLASWTDAPGFPVLNVYRLYRDGMMILSQERFLEQSVLP-------TGHVWHI 567

  Fly   532 PLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTD--WILFNVQHTAPFRVNYD 594
            |.:|...|......::.:.||       ||::     .|||....|  |::||.|.|..:|||||
Mosquito   568 PFNYAYESSATFYDLTTAGWL-------SSRA-----AKLETPVPDDEWVVFNKQQTGYYRVNYD 620

  Fly   595 LRNWQLLNKTL-ADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYLEHEDEFVVWVA 658
            .|||.||.:.| |:.|   .|||.|||||:||.|:||.:..::..:.|.::.||..|.::..|.|
Mosquito   621 RRNWDLLAQALMANRN---AIHRANRAQLIDDAFNLARADLLDMAVVLRLMRYLRAERDYAPWYA 682

  Fly   659 TEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMT----HRPVIIRLACEY 719
            .:.....:.:..::..:...|..|:..|:|..: ..:|.| |...|..|    .|.:|...||..
Mosquito   683 ADKVLTYLYDKVRATEHEHAFLVYVDELIEEVY-ATLSVD-TVGQGESTLYKYLRQLITGWACRI 745

  Fly   720 ELPACV----SLARREFMKGTPEKGGWMTIRERETVVCTAVKFGTEGDRDMVESMYKRSNFAAEK 780
            ....|:    :..|:|.:.|..|....:....|..|.|..::..:..:..::......|...||:
Mosquito   746 GYKDCLERSRAALRKELLPGQGESSVAVHPDVRAVVYCYGLQQDSAEEFQLIFQRLMASRNQAER 810

  Fly   781 ESLLTALACSRNVFALQRVLIWTFESSG------VRKQNARRTFKAVVSNSMGYRLAKKYV---S 836
            ..|:.||.|:||..::..:|.....|:.      ...:...|.|:|:.|......||...|   .
Mosquito   811 TDLIDALGCARNADSITSLLATIVFSAAPDTTFVYLSEERNRVFQAIYSGGRAPTLALMNVLSDP 875

  Fly   837 VNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRDMNG 886
            |::|.:.......|  :.|.:..:.:..:..:|:..    .:.:|..|||
Mosquito   876 VSVQQLLAIVGEGT--ITNAVMNIAQRTNGAEEMAR----LEMMLTAMNG 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	115/464 (25%)
		ERAP1_C	578..897	CDD:463368	85/327 (26%)
LOC11175588	XP_061502291.1	None