Protein Alignment CG2111 and rnpepl1

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: NP_001335117.1
• Gene: rnpepl1 / 100535895
• ZFINID: ZDB-GENE-030131-5522
• Length: 692
• Species: Danio rerio
• Alignment Length: 681
• Identity: 149/681 - (21%)
• Similarity: 232/681 - (34%)
• Gaps: 213/681 - (31%)

  Fly    14 FHLEAN-KTAVGRLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIG 77
            |||:.: ..||.|:..|.|     :::.     |.||...::::|....     :::::.|.
Zfish    51 FHLDLHLNFAVKRITGWQV-----LELT-----PVQPGVQSLILDTHPS-----LLIHSVDC--- 97

  Fly    78 KRRAVTLSDKNGNSVPVSSIQMDIKLSRLTVSLKRPL-----KVNVTYSMRV-----AFTSVLRN 132
                         .||.:|...|:.|| ||..:: |.     .:|:|....|     ||...:|.
Zfish    98 -------------KVPGASGAPDVFLS-LTYRVE-PFTDYGSSLNITLPAAVIRPHRAFRVTVRY 147

  Fly   133 DNTGFYSSNYVDHNTTL--TQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNM 195
            ..|...:..::|...|.  |:.|..||......|..|||||.|..::.:...:..|.....|  |
Zfish   148 TTTDGPAIWWLDAELTCGQTRPLVFTQGHSVCNRSFFPCFDTPAVKSTYSATVRVPEGVTVL--M 210

  Fly   196 PVQRTIRHASLKDYVWTQFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDALSQTE 260
            ...|:.  .|.:|.|: ||...:|:..||||.:.............|      .||.|..|:
Zfish   211 SASRSA--YSKQDRVF-QFSMEYPVPAYLVALVAGDLQHADIGPRSR------VWAEPCILT--- 263

  Fly   261 FANMVVAPL-------LSFYEDLFNSTYRQKKIDLVAL-PDFTFKSKENWGLPAFAEESLLYDSQ 317
               ..|:.|       |:..|.|| ..|...:.|||.| |.|...:.||..| .|...|:|...:
Zfish   264 ---CAVSKLGGSVERWLNVAEGLF-GPYVWGRYDLVFLPPSFPIVAMENPCL-TFIISSILESQE 323

  Fly   318 RSSIDDQQGVARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHAL 382
            ...||        |...:.:.||||.|:.|.|.|:||....|.|..|
Zfish   324 FLLID--------VIHEIAHGWFGNAVTNATWEEMWLSEGLATYAQR------------------ 362

  Fly   383 QLYLSVLDYDAHVNTDLVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLV 447
                       .:.|:              ||.|     |....|.:.|       |.||.|.:.
Zfish   363 -----------RITTE--------------AYGE-----AFTCLETVFR-------LDALHRQMR 390

  Fly   448 VYANRTATSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLV--------------TVT 498
            :..:....|       :||    .:...|:|.:.:|..:..:.|:..|              :..
Zfish   391 LLGDNNPVS-------KLQ----AKFEPGVNPSSLMNLFTYEKGFCFVSYLSQLCGDIKRFDSFL 444

  Fly   499 RNYDHR---TAIVSQQ--RFFITPQFRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLT-C--P 555
            |.|..:   :::::|.  .||:.            ::..|...|.:  ..|.:.|.|||. |  |
Zfish   445 RAYIEKFRFSSVIAQDLLDFFLG------------FFPELKEGCVA--QREGLEFERWLNGCGPP 495

  Fly   556 TSKPSSKSNTVLLEKLEAEPTDWILFNVQHTAPFRVN----------YDLRNWQLLNKTLADPNK 610
            ..:|...:...|...            |||......|          :||.:|......|
Zfish   496 LCEPDLSAGRTLTGP------------VQHLCDLWGNDAPDTQVISTFDLSSWSTFQTVL----- 543

  Fly   611 F--RLIHRVNRAQLVDDLFSLAWSGDIEYDM 639
            |  ||:.|...:|.|..|.|..::..:: ||
Zfish   544 FLDRLLDRSPLSQEVMSLLSSCYAALLD-DM 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	105/473 (22%)
		ERAP1_C	578..897	CDD:463368	18/74 (24%)
rnpepl1	NP_001335117.1	M1_LTA4H	36..490	CDD:341062	126/578 (22%)
		Leuk-A4-hydro_C	536..649	CDD:462686	12/44 (27%)