Protein Alignment CG2111 and anpep

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_031755081.1
• Gene: anpep / 100492262
• XenbaseID: XB-GENE-981369
• Length: 977
• Species: Xenopus tropicalis
• Alignment Length: 933
• Identity: 267/933 - (28%)
• Similarity: 426/933 - (45%)
• Gaps: 110/933 - (11%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPF-----GGTVVIDLRSERSTKRIVLN-AHDLAIGKRRAVT 83
            ||||.|.|:.|.|::        |||     .|..|.   ..:||...:.| |.||.|.....:.
 Frog    84 RLPKTLSPVHYDVEL--------QPFLVKNADGLYVF---RGKSTAFFICNDATDLIIIHSNKLN 137

  Fly    84 LSDKNGNSVPVSSIQMDIKLSR---------LTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYS 139
            .:..|.....:.....|:.|..         |.|.....|.....|.:...|...|.:|..|||.
 Frog   138 HTKFNSFDAKLQDGATDVALKSTFFQKDKQFLVVQAAANLVPGKQYGLYTEFVGELADDLAGFYR 202

  Fly   140 SNYVDHNTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHA 204
            |.|::..  :|:.:|.||.:...||:||||||:|..:..|.|.|.:...|:|:|||   |.|..:
 Frog   203 SEYLEDG--VTKIIATTQMQAPDARKAFPCFDEPAMKATFNITLKYRQPYKAMSNM---REIDRS 262

  Fly   205 SLKD--YVWT--QFVESHPMQTYLVAFMISKFDRPGFTSSERSDCPISTWARPDAL---SQTEFA 262
            ::.:  ..||  :|.::..|.:|||||::|:|:..| .....:...:..|.|..|:   :|.|:|
 Frog   263 TVTEDGQQWTVSKFDKTPKMSSYLVAFIVSEFEAVG-DPGNATVTGVQIWGRKKAIQDENQGEYA 326

  Fly   263 NMVVAPLLSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGV 327
            ..|..|:|.|:.:.:.:.|...|.|.||||||:..:.|||||..:.|.:||:|.|.|||.:::.|
 Frog   327 LSVTKPILDFFAEYYRTPYPLPKSDQVALPDFSAGAMENWGLVTYRETALLFDDQVSSIGNKERV 391

  Fly   328 ARAVAMMVVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYLSVLDYD 392
            ...:|..:.:|||||||::.||:::||...||.|:...|.....|.|:.::...|.....|:..|
 Frog   392 VTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADKAEPNWNIKDLIVLNDVHRVMAVD 456

  Fly   393 AHVNTDLVTA---SVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTA 454
            |..::..:|:   .|...|.|.|.::.|...|.|.:..||...:.|..::..|..||..:.....
 Frog   457 ALASSHPLTSREDEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVDGLASYLKGFEYSNT 521

  Fly   455 TSSDFWDLLQLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFITPQ- 518
            ..||.|..||..|:....:...|.|..||..|:.|.|:|:|.:    |..|.:|:|:.|.:.|.
 Frog   522 VYSDLWTHLQWAVNNQTAVKLPLPIKDIMDTWVLQMGFPVVKI----DTATGVVTQKHFLLDPDS 582

  Fly   519 -------FRNRWARNPCWWVPLSYTCPSCQHSEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPT 576
                   |..:|.      ||:||...|.:.      :.||       .::|.||  |..:....
 Frog   583 VVTRPSPFDYKWK------VPISYKISSKED------NIWL-------QNESETV--EDFKITGN 626

  Fly   577 DWILFNVQHTAPFRVNYDLRNW-QLLNKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMA 640
            ||:|.|:..|..:|||||..|| :|||:.   ....:.|..:||||::||.|:||.:..|....|
 Frog   627 DWLLVNLNVTGYYRVNYDDNNWSRLLNQL---QTSHQAIPVINRAQIIDDAFNLARAKQITTIQA 688

  Fly   641 LGILGYLEHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGN 705
            |....|:..:.|::.|.|..........:......:...|.||::.:...|:.     ....:||
 Frog   689 LDTTKYISADREYMPWQAALSGLSYFTQMFDRTEVFGPMKKYMKMQVNPLFEY-----FKQETGN 748

  Fly   706 MTHRPV----------IIRLACEYELPACVSLARREFMKGTPEKGGWMTIRE--------RETVV 752
            .|:|||          .:..||.|::..|:..|...|.:       ||...:        |..|.
 Frog   749 WTNRPVSLTDQYCEINTLSTACSYDIEDCLKFASELFSQ-------WMATPQQNNIHPNLRTNVY 806

  Fly   753 CTAVKFGTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRT 817
            ||||..|.|.:.:.|...::.::.|.|::.|..|||||:..:.|.|.|.::.:.:.:|:|:|..|
 Frog   807 CTAVAQGGEQEWNFVWDRFQLTDIAQEQDKLRAALACSKEPWILNRFLEYSLDPTMIRRQDAVST 871

  Fly   818 FKAVVSNSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILR 882
            ..:||:|.:|..||..:|....:.:.:....|:....||:..:....||..||....:|..:...
 Frog   872 ISSVVNNPIGQSLAWDFVRAKWKTLYSMFGESSFSFGNLIERVTRRFSTEFELQQLLQFKADNQN 936

  Fly   883 DMNG-SERLIKILLERGNDNIHW 904
            ...| :.:.::..:|:...||:|
 Frog   937 PGFGTASQALEQAIEKTKANINW 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	143/478 (30%)
		ERAP1_C	578..897	CDD:463368	89/338 (26%)
anpep	XP_031755081.1	M1_APN-Q_like	92..555	CDD:341064	144/479 (30%)
		ERAP1_C	628..955	CDD:463368	90/341 (26%)