Protein Alignment CG2111 and trhde.1

DIOPT Version :10

• Sequence 1: NP_572644.1
• Gene: CG2111 / 31995
• FlyBaseID: FBgn0030223
• Length: 931
• Species: Drosophila melanogaster
• Sequence 2: XP_001345457.3
• Gene: trhde.1 / 100006808
• ZFINID: ZDB-GENE-170406-2
• Length: 994
• Species: Danio rerio
• Alignment Length: 931
• Identity: 270/931 - (29%)
• Similarity: 438/931 - (47%)
• Gaps: 114/931 - (12%)

  Fly    25 RLPKWLVPLSYRVDIVTRINQPYQPFGGTVVIDLRSERSTKRIVLNAHDLAIGKRRAVTLSDKNG 89
            |||..|.|..|  |:...::.....|.|.|.|:.....|||.|||::..|.:.|....:.|.|.|
Zfish   109 RLPATLRPRHY--DLRLTVHMENFSFSGEVNIEFECVNSTKLIVLHSDRLELDKVLVFSDSKKAG 171

  Fly    90 NSVPVSSIQMDIKLSR---------LTVSLKRPLKVNVTYSMRVAFTSVLRNDNTGFYSSNYVDH 145
                      .:::.|         ..::|.|.:|...||.:.:.||:.:.::..||:.|:|:.:
Zfish   172 ----------AMRIQRRFHYQPKQVYVIALHREMKPLRTYKINITFTAHIEHELLGFFRSSYMLN 226

  Fly   146 NTTLTQWLAATQFEPNHAREAFPCFDDPIFRTPFKINLAHPYLYRALSNMPVQRTIRHASLKD-Y 209
            ..  .::||.|||.|.|||:||||||:||::..|:::|.|...|::||||||:.|   .|.:| :
Zfish   227 GE--RRFLAVTQFSPTHARKAFPCFDEPIYKATFRVSLKHESSYQSLSNMPVEAT---TSDEDGW 286

  Fly   210 VWTQFVESHPMQTYLVAFMISKFDRPGFTSSER---SDCPISTWARPDAL--SQTEFANMVVAPL 269
            |...|..:..|.||.:|:.:.     .||..|.   :...|..:|||||:  ...::|..:...|
Zfish   287 VTNHFSRTPRMSTYYLAWAVC-----NFTYKEAVADNGVLIRLYARPDAIQSGSGDYALRITKRL 346

  Fly   270 LSFYEDLFNSTYRQKKIDLVALPDFTFKSKENWGLPAFAEESLLYDSQRSSIDDQQGVARAVAMM 334
            |.||:|.|...|...|:||:|:|...:.:.|||||..|.|:.:|.|.:.||...|..:...|...
Zfish   347 LQFYQDYFKVKYSLPKLDLLAVPKHPYSAMENWGLSVFVEQKILLDPEVSSFSYQMELTVVVVHE 411

  Fly   335 VVNQWFGNLVSVAWWHEIWLKNVFALYLSRFGVHSLRPEWDYQERHALQLYL-SVLDYDAHVNTD 398
            :.:||||:||:..||.::|||..||.|....|...|.|:|:.:::..|...| .|:..|...::.
Zfish   412 ICHQWFGDLVTPVWWEDVWLKEGFAHYFEYIGADFLFPKWNMEKQRFLTDVLHEVMLLDGLASSH 476

  Fly   399 LVTASVPDESHIWAAYNEIGERKAAVLFEMLHRVMGEEAWLTALRRYLVVYANRTATSSDFWDLL 463
            .::..|.:.:.|...::.|..:|.|.|..||..|||:..:..||..||:.:....|...|.|:.|
Zfish   477 PISQQVFEATDIDRVFDWIAYKKGAALIRMLANVMGQTLFQRALNDYLMTHMYGNAARDDLWNKL 541

  Fly   464 QLQVDRNGRLGKGLNITRIMKCWLGQPGYPLVTVTRNYDHRTAIVSQQRFFI--------TPQFR 520
            ...:.|.   ||.:|||::|..|..|.|||:||:::|.....:|...|..|:        .|:..
Zfish   542 SEAMQRE---GKDINITQVMDRWTLQMGYPVVTISKNDSLDNSITISQEHFVYDTDAKIQNPELF 603

  Fly   521 NRWARNPCWWVPLSYTCPSCQH--SEIISFSRWLTCPTSKPSSKSNTVLLEKLEAEPTDWILFNV 583
            |:..:   |.:||:....:..|  :|.|.   |:|       :||....:..:..|  .|:|.|:
Zfish   604 NKSFQ---WQIPLTLAVGNASHISTETII---WVT-------NKSEAHRVGHMVGE--TWLLGNI 653

  Fly   584 QHTAPFRVNYDLRNWQLL-NKTLADPNKFRLIHRVNRAQLVDDLFSLAWSGDIEYDMALGILGYL 647
            ..|..|||||||.||:|| .:.:::|.   :|...|||.|:||:|:||.:|.:..::.|.::.||
Zfish   654 NQTGYFRVNYDLHNWKLLIQQLMSNPT---IISVGNRAGLIDDVFNLARAGYLPQNVPLQMISYL 715

  Fly   648 EHEDEFVVWVATEISFERINNVAKSNPNYLIFKTYMRLLLERQFKRVISSDLTSSSGNMTH---- 708
            ..|.||:.|.|...:..:::.:.....::.:|..|:...:|.::.: :....||..|:..|
Zfish   716 SQEPEFLPWHAASRALYQLDKLLDRTLDHSLFSDYVLRQVEPKYHK-LGWPATSPDGSFMHSAYQ 779

  Fly   709 ----RPVIIRLACEYELPAC----VSLARREFMKGTPEKGGWMTIRE-------RETVVCTAVKF 758
                :..:|.|||.:....|    |||.           ..|::..:       |:.|.||.|..
Zfish   780 TEELQREVIMLACSFGNKHCHRQAVSLI-----------SDWISSNKNRIPPNVRDIVYCTGVSL 833

  Fly   759 GTEGDRDMVESMYKRSNFAAEKESLLTALACSRNVFALQRVLIWTFESSGVRKQNARRTFKAVVS 823
            ..|...:.:...:..|...:||:.||.||.||.|:|.|.|:|..:..|..|..|:.......|..
Zfish   834 MDEDVWEFIWMKFHSSTAVSEKKVLLEALTCSDNIFLLNRLLNLSLTSDLVPDQDVIDVIIHVAR 898

  Fly   824 NSMGYRLAKKYVSVNMQNIRNYCSNSTDKVVNLMTPLIECLSTPKELLYFSKFFKEILRDMNGSE 888
            |.:|..||.:|.......:.:....:......|::.:.|.|:|..||    ...||.:....|..
Zfish   899 NPLGRHLAWRYFREKWDILNSRYGEALFMNSKLISGVTEFLNTEAEL----NELKEFILTSGGES 959

  Fly   889 -----RLIKILLERGNDNIHW 904
                 |.::|:    ..|:.|
Zfish   960 APAFARAVEIV----QANVKW 976

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2111	NP_572644.1	M1_APN-Q_like	33..487	CDD:341064	148/469 (32%)
		ERAP1_C	578..897	CDD:463368	91/343 (27%)
trhde.1	XP_001345457.3	M1_APN-Q_like	118..563	CDD:341064	149/469 (32%)
		ERAP1_C	648..975	CDD:463368	92/349 (26%)