Protein Alignment CG9806 and AAP1

DIOPT Version :10

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 919
• Identity: 211/919 - (22%)
• Similarity: 372/919 - (40%)
• Gaps: 140/919 - (15%)

  Fly    25 SNLRPLHYNLSLLTEVEPLKLSGNFSGEVIIRLRVWRETRTIILSNNGLQV-------------G 76
            :|:.||||:::|    ||...:..|.|.:.|.|::...      |.|.:|:             |
Yeast     8 NNVTPLHYDITL----EPNFRAFTFEGSLKIDLQINDH------SINSVQINYLEIDFHSARIEG 62

  Fly    77 ENVLLVRRNTGGRVTVRKMWQASSVHQLGIVFNSMLWLGEEYTLVVQFSGQLS-RASGYFVGGYM 140
            .|.:.|.:|       ....:|:.|...|...|    ||....|.:.|||.|: :.:|::...|.
Yeast    63 VNAIEVNKN-------ENQQKATLVFPNGTFEN----LGPSAKLEIIFSGILNDQMAGFYRAKYT 116

  Fly   141 DS-KHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKTSDHEKDDY 204
            |. ....:::|.||:....|...||||:.....|.|.:.|........:|||.|...:..|...|
Yeast   117 DKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKY 181

  Fly   205 VWTTFQQTPAMSVQKLAFSIN--RFTNRTSAEIPKGPALTTWLRPKIADQGDYAISITPQIIVFF 267
              |||..||.||...:||.:.  |:....:..||    :..:..|.....|.:|.::..:.:.||
Yeast   182 --TTFNTTPKMSTYLVAFIVADLRYVESNNFRIP----VRVYSTPGDEKFGQFAANLAARTLRFF 240

  Fly   268 ISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQQVASHVAQEFAHH 332
            ...|...||..|:|.:.:.:.:..:.|:.|||:|.....|...:.|:....|:||..:..|.||.
Yeast   241 EDTFNIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQ 305

  Fly   333 WLSDLENAALY---WLHNGLSDYVSGFAVDNVEPAWRFHELSMVRQALAVLVEDSKSSAYPMSLA 394
            |..:|.....:   ||:.|.:.::|.::.:..:|.|:..|..:.......|..||..|::|:.:.
Yeast   306 WFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVP 370

  Fly   395 YASKSS-----DTQANQKSALLFRMLHSLIGTQAFLNALRLYLQRSHKGSSSNQAFLWHTLQEES 454
            ..:...     |..:..|.:.|.||:...:|.:.|:..:..||.:...|::.. ..||..|.:.|
Yeast   371 VNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKT-GDLWDALADAS 434

  Fly   455 DNQMSLRQDIKVSQLMDSWTMQPGYPLIRVVRNYDTNEVTVTQERFLRNPGKLMQKRQQCWWVPL 519
            ...        |..:|:.||.:.|:|::.|..:  .|::|:||.|:| :.|.:.::.....: |:
Yeast   435 GKD--------VCSVMNIWTKRVGFPVLSVKEH--KNKITLTQHRYL-STGDVKEEEDTTIY-PI 487

  Fly   520 TFA---TAGIDSFVSTLPSEWLTCQGRQTASPLILNEVAQPDKWVVFNLRLATPCRI-------- 573
            ..|   :.|||                   :.|:|||     |...|.|:.....:|
Yeast   488 LLALKDSTGID-------------------NTLVLNE-----KSATFELKNEEFFKINGDQSGIF 528

  Fly   574 --TYDERNWQLIGNALSGTNASSIDRFTRAQLISDVLNLAGAGVVTYDLALNFLGHLRNEDEFIV 636
              :|.:..|..:...   .|..|::  .|..|::|...|:.:|..:....||.:.:.:|||.|:|
Yeast   529 ITSYSDERWAKLSKQ---ANLLSVE--DRVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVV 588

  Fly   637 WQAADTYLEWLHRT--LRQTTIISTFKGFMRDLLQTKFDEL---FKRDGSAAENANITELMVIVL 696
            |:.....|..|..|  .....|::....|..||:..|..||   ...|.|.|    |..|.|.:.
Yeast   589 WEQIINSLSALKSTWVFEPEDILNALDKFTLDLVLNKLSELGWNIGEDDSFA----IQRLKVTLF 649

  Fly   697 QLSCRTDLESCADFAL---KEFAGLTLETNRIPVDLSETIYCTAIQFGTEADWTLLRRLYTRSNV 758
            ..:|.:..|.....|:   :|:|....:.  ||......::.|..:.|.|.::..:..:|.....
Yeast   650 SAACTSGNEKMQSIAVEMFEEYANGNKQA--IPALFKAVVFNTVARLGGENNYEKIFNIYQNPVS 712

  Fly   759 SEERRILLSAMACSRENWALDKLLNLAFAGRYMPKDDVLLIFSAVAQNPL-GYNIAKK------- 815
            |||:.|.|.|:....:...|::.|:....|..:.:|..:         |: |..:.||
Yeast   713 SEEKIIALRALGRFEDKELLERTLSYLLDGTVLNQDFYI---------PMQGIRVHKKGIERLWA 768

  Fly   816 YLVDNIKAIIKLYGSNTDELAQLVTVLMKEVTTEEELNALRMFMRTDLQNLPGFEIAFRRILELG 880
            ::.::...|.|.....:..|..::|:.:...|:.|.|..:..|....:..  ||:....:.|:..
Yeast   769 WMQEHWDEIAKRLQPGSPVLGGVLTLGLTNFTSFEALEKISAFYSRKVTK--GFDQTLAQALDTI 831

  Fly   881 EDNISWHNR 889
            .....|.:|
Yeast   832 RSKAQWVSR 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	M1_APN-Q_like	30..474	CDD:341064	113/468 (24%)
		ERAP1_C	560..878	CDD:463368	71/343 (21%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	114/469 (24%)
		ERAP1_C	517..833	CDD:463368	70/337 (21%)