Protein Alignment CG9806 and LAP2

DIOPT Version :10

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_014353.1
• Gene: LAP2 / 855682
• SGDID: S000004990
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 836
• Identity: 175/836 - (20%)
• Similarity: 276/836 - (33%)
• Gaps: 272/836 - (32%)

  Fly    22 ATASNLRP---LHYNLSLLTEVEPLKLSGNFSGEVIIRLRVWRETRT----IILSNNGLQVGENV 79
            :|.||.:.   ||.:|:|....|...:||:    |..:|:...|.:.    :.|..:.|.|.| |
Yeast    59 STLSNYKDFAVLHTDLNLSVSFEKSAISGS----VTFQLKKLHEGKNKSDELHLDTSYLDVQE-V 118

  Fly    80 LLVRRNTGGRVTVRKMWQASSVHQLG--IVFNSMLWLGEEYTLVVQFSGQLSRASGYFVGGYMDS 142
            .:.......::..||       ..||  :|.|:.. ..:.:||.:||     |.:        |.
Yeast   119 HIDGSKADFQIEQRK-------EPLGSRLVINNAS-CNDNFTLNIQF-----RTT--------DK 162

  Fly   143 KHHPQWI-----------AVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKT 196
            ....||:           ..:||....|.::||||:..:..:.|..::..|... ..|.:|:..|
Yeast   163 CTALQWLNSKQTKGGKPYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESPLPV-VFSGIRIEDT 226

  Fly   197 SDHEKDDYVWTTFQQTPAMSVQKLAFSINRFTNRTSAEIPKGPALTTWLRP-KIAD-QGDYAISI 259
            |   ||..::...|:.|..     |:.|...:...|: .|.||..|.:..| ::.| |.::...:
Yeast   227 S---KDTNIYRFEQKVPIP-----AYLIGIASGDLSS-APIGPRSTVYTEPFRLKDCQWEFENDV 282

  Fly   260 -----TPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQ 319
                 |.:.|:|       .|.....|.||..|    |:.:.|:.| |...|......:..|:..
Yeast   283 EKFIQTAEKIIF-------EYEWGTYDILVNVD----SYPYGGMES-PNMTFATPTLIAHDRSNI 335

  Fly   320 QVASHVAQEFAHHWLSDL-ENAAL--YWLHNGLSDYVSGFAVDNV--EPAWRFHEL---SMVRQA 376
            .|.:|   |.||.|..:| .|.:.  :||:.|.:.|:....:..:  ||...|..|   |.::.:
Yeast   336 DVIAH---ELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNS 397

  Fly   377 LAVLVEDSKSSAYPMSLAYASKSSD---TQANQKSALLFRMLHSLIGTQA-FLNALRLYLQRSHK 437
            :..:.:..:.|....:|...:...|   |...:|...|...|.:::|.:| |...:|.|.::..|
Yeast   398 IDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAK 462

  Fly   438 GSSSNQAFLWHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYPLIRVVRNYDTNEVTVTQERFLR 502
            .|.....|| .||.|....    :::|..|...::|..:||.|                     .
Yeast   463 KSLDTFQFL-DTLYEFYPE----KKEILDSVDWETWLYKPGMP---------------------P 501

  Fly   503 NPGKLMQKRQQCWWVPLTFATAGIDSFVSTLPSEWLTCQGRQTASPLILNEVAQPDKWVVFNLRL 567
            .|               .|.||..|                        |.....||||    .:
Yeast   502 RP---------------HFITALAD------------------------NVYQLADKWV----EM 523

  Fly   568 ATPCRITYDERNWQLIGNALSGTNASSIDRFTRAQLISDVLNLAGAGVVTYDLALNFL---GHLR 629
            |...:.|.|.|         |..||..|..|...||:               |.|..|   ||..
Yeast   524 AQHLKTTEDFR---------SEFNAIDIKDFNSNQLV---------------LFLETLTQNGHSN 564

  Fly   630 NEDEFIVWQAADTYLEWLHRTLRQTTIISTFKGFMRDLLQTKFDELFKRDGSAAENANITELMVI 694
            .:.:...|                    :.|....|.||....|.:.|     ::||.:...|
Yeast   565 KKPKDFDW--------------------AKFPVASRALLDIYQDNIVK-----SQNAEVVFKM-- 602

  Fly   695 VLQLSCRTDLESCADFALKEFAGLTLETNRIPVDLSETIYCTAIQFGTEADW--TLLRRLYTRSN 757
                           |..:.||.|..|...:                  |||  |:.|..:.|..
Yeast   603 ---------------FKFQIFAKLQEEYKHL------------------ADWLGTVGRMKFVRPG 634

  Fly   758 V----SEERRILLSAMACSRENWALDKLLNLAFAGRYMPKDDVLLIFSAVAQNPLG 809
            .    |.:||:.|:         ..||     |...|.|      |..|:.:..||
Yeast   635 YRLLNSVDRRLALA---------TFDK-----FKDTYHP------ICKALVKQDLG 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	M1_APN-Q_like	30..474	CDD:341064	108/479 (23%)
		ERAP1_C	560..878	CDD:463368	52/259 (20%)
LAP2	NP_014353.1	leuko_A4_hydro	57..669	CDD:274120	173/833 (21%)