Protein Alignment CG9806 and AOPEP

DIOPT Version :10

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001372995.1
• Gene: AOPEP / 84909
• HGNCID: 1361
• Length: 859
• Species: Homo sapiens
• Alignment Length: 561
• Identity: 107/561 - (19%)
• Similarity: 176/561 - (31%)
• Gaps: 176/561 - (31%)

  Fly    51 GEVIIRLRVWRETRTIILSNNGLQVGENVLLVRRNTGGRVTVR-----KMWQASSVHQLGIVFNS 110
            ||::.....|           .||:        |.||.:....     ::|..:....     .|
Human   216 GELLFDTDTW-----------SLQI--------RKTGAQTATDFPHAIRIWYKTKPEG-----RS 256

  Fly   111 MLWLGEEYTLVVQFSGQLSRASGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPCFENRTFLAPF 175
            :.|.          |.|..|...|.||..::::                 .:|||.|      |.
Human   257 VTWT----------SDQSGRPCVYTVGSPINNR-----------------ALFPCQE------PP 288

  Fly   176 ILNLAHPRGTNAVSNMRVLKTSDHE-KDDYVWTT-----FQQTPAMSVQKLAFSINRFT------ 228
            :..........|.::..||.:.::. |...:|..     :..|..|.......::..:|
Human   289 VAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMET 353

  Fly   229 ---NRTSAEIPKGPALTTWLRPKIADQGDY------AISITPQII---VFF-ISLFGK------- 273
               |..:.|.|..|:...:....:....:|      |.:.|.:||   ||. :.|.|.
Human   354 WSSNDLATERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLR 418

  Fly   274 --------------PYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQQVASH 324
                          .:|..::|.|::|    .:...||:.| |...||  :|...|.......:.
Human   419 LIPPCLSAAHSVLGAHPFSRLDVLIVP----ANFPSLGMAS-PHIMFL--SQSILTGGNHLCGTR 476

  Fly   325 VAQEFAHHWLSDLENAALYWLHNGLSDYVSGFAVDNVEPAW---------RFHELSMVRQAL--A 378
            :..|.||.|.. |...|..|....||:   |||....:..|         ...|...:|..|  .
Human   477 LCHEIAHAWFG-LAIGARDWTEEWLSE---GFATHLEDVFWATAQQLAPYEAREQQELRACLRWR 537

  Fly   379 VLVEDSKSSAYPMSLAYASK-----SSDTQAN-----------------QKSALLFRMLHSLIGT 421
            .|.::.:.|...|.:...||     :||:.|:                 .|...|.|.|...:|.
Human   538 RLQDEMQCSPEEMQVLRPSKDKTGHTSDSGASVIKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGD 602

  Fly   422 QAFLNALRLYLQRSHKGSSSNQAFLWHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYP------ 480
            :.:.:.||.::...|.....:|.||...|:...:.:   |.::.|..:...|....|.|
Human   603 ETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEK---RLELSVENIYQDWLESSGIPKPLQRE 664

  Fly   481 --------LIRVVRNYDTNEVTVTQERFLRNPGKLMQKRQQ 513
                    |.|.||...|..:.|.     |.|.|  :||::
Human   665 RRAGAECGLARQVRAEVTKWIGVN-----RRPRK--RKRRE 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	M1_APN-Q_like	30..474	CDD:341064	93/506 (18%)
		ERAP1_C	560..878	CDD:463368
AOPEP	NP_001372995.1	GluZincin	<244..652	CDD:472708	85/459 (19%)
		Nucleolar localization signal. /evidence=ECO:0000250|UniProtKB:Q8BXQ6	689..699		5/12 (42%)
		Leuk-A4-hydro_C	721..>771	CDD:462686