Protein Alignment CG9806 and Erap1

DIOPT Version :9

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_006231762.1
• Gene: Erap1 / 80897
• RGDID: 708542
• Length: 954
• Species: Rattus norvegicus
• Alignment Length: 977
• Identity: 231/977 - (23%)
• Similarity: 424/977 - (43%)
• Gaps: 159/977 - (16%)

  Fly     2 IKLPWYLIVLHLCLPIGGTGATASNLRPLHYNLSLLTEVEPLKLSGNFSGEVIIRLRVWRETRTI 66
            ::||.|:..:|..|.|             |.|||.||          |.|:..:.:.|.:.|.||
  Rat    41 MRLPEYITPIHYDLMI-------------HANLSTLT----------FWGKTEVEITVSQPTSTI 82

  Fly    67 ILSNNGLQVGENVLLVRRNTGGRVTVR--KMWQASSVHQLGIVFNSMLWLGEEYTLVVQFSGQLS 129
            |:.::.||:.:..|  ||.....:...  |:.:.|:..|:.::....|..|..||:::.::..||
  Rat    83 IMHSHQLQISKATL--RRGAEEMLPEEPLKLMEYSAHEQVALLTAQPLLAGSVYTVIITYAANLS 145

  Fly   130 -RASGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRV 193
             ...|::...|...:...:.:|.||..|..|...||||:.....|.|.:.:.......|:|||.:
  Rat   146 ENFHGFYKSTYRTQEGERRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNMPL 210

  Fly   194 LKT--------SDHEKDDYVWTTFQQTPAMSVQKLAFSINRFTNRTSAEIPKGPALTTWLRPKIA 250
            :|:        .||         |..|..||...:||.|:.|.: .|.....|..::.:..|...
  Rat   211 VKSVTVAEGLIEDH---------FDITVKMSTYLVAFIISDFKS-VSKMTKSGVKVSVYAVPDKI 265

  Fly   251 DQGDYAISITPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTT 315
            :|.|||:.....::.|:...|..|||..|.|...:||....:.|:.||.:|.|:|.||..::|:.
  Rat   266 NQADYALDAAVTLLEFYEDYFSIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESALLYDKEKSSA 330

  Fly   316 RAKQQVASHVAQEFAHHWLSDLENAALY---WLHNGLSDY------------------------- 352
            .:|..:...|:.|.||.|..:|.....:   ||:.|.:.:
  Rat   331 SSKLGITMTVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVTVTHPELKVMQILTANHQN 395

  Fly   353 ----VSGFAVDNVEPAWRFHELSMVRQALAVLVEDSKSSAYPMSL-----AYASKSSDTQANQKS 408
                :||.|::..|..:.|.:..   .|:.|   |:.:|::|:|.     |...:..|..:.:|.
  Rat   396 EPEDLSGRAMERTEEEYFFGKCF---NAMEV---DALNSSHPVSTPVENPAQIREMFDEVSYEKG 454

  Fly   409 ALLFRMLHSLIGTQAFLNALRLYLQR-SHKGSSSNQAFLWHTL------------------QEES 454
            |.:..||...:....|...:..|||: |:|.:.:..  ||:::                  .:.|
  Rat   455 ACILNMLRDYLSADTFKRGIVQYLQKYSYKNTKNED--LWNSMMHICPTDGTQTMDGFCSRNQHS 517

  Fly   455 DNQMSLRQD-IKVSQLMDSWTMQPGYPLIRV-VRNYDTNEVTVTQERFLRNPGKLMQKRQQCWWV 517
            .:....||: |.:..:|::||:|.|:|||.: ||.   ..|.:.||.:::. .:...:....|.|
  Rat   518 SSTSHWRQEVIDIKSMMNTWTLQKGFPLITITVRG---RNVHLKQEHYMKG-SECFPETGSLWHV 578

  Fly   518 PLTFATAGIDSFVSTLPSEWLTCQGRQTASPLILNEVAQPDKWVVFNLRLATPCRITYDERNWQL 582
            ||||.|:..||....|.        :.....:||.|..:   |:.||:.:.....:.|.:..|..
  Rat   579 PLTFITSKSDSVQRFLL--------KTKTDVIILPEAVE---WIKFNVGMNGYYIVHYGDDGWAS 632

  Fly   583 IGNAL--SGTNASSIDRFTRAQLISDVLNLAGAGVVTYDLALNFLGHLRNEDEFI-VWQAADTYL 644
            :...|  :.|..||.|   ||.||::...|...|.::.:.||:.:.:|:||.|.: ::|..:..:
  Rat   633 LNGLLKEAHTTISSND---RASLINNAFQLVSIGKLSIEKALDLILYLKNETEIMPIFQGLNELI 694

  Fly   645 EWLHRTLRQTTII---STFKGF----MRDLL--QTKFDELFKRDGSAAENANITELMVIVLQLSC 700
            . :::.:.:..::   :.||.|    ::||:  ||..||     ||.:|....::|::    |:|
  Rat   695 P-MYKLMEKRDMVEVETQFKDFLLRLLKDLINKQTWTDE-----GSVSERMLRSQLLL----LAC 749

  Fly   701 RTDLESCADFALKEFAGLTLETNR--IPVDLSETIYCTAIQFGTEADWTLLRRLYTRSNVSEERR 763
            ....:.|...|.:.|.........  :|:|::..::....| .||. |..|...|..|..|.|:.
  Rat   750 VHRYQLCVQRAERYFREWKASNGNMSLPIDVTLAVFAVGAQ-NTEG-WDFLYSKYQSSLSSTEKS 812

  Fly   764 ILLSAMACSRENWALDKLLNLAFAGRYMPKDDVLLIFSAVAQNPLGYNIAKKYLVDNIKAIIKLY 828
            .:..::..|::...|..||:.:|.|..:...:...|.:.:.:||:||.:|.|:|.:|...|::.:
  Rat   813 QIEFSLCISQDPEKLQWLLDQSFKGEIIKTQEFPHILTLIGRNPVGYPLAWKFLKENWNKIVQKF 877

  Fly   829 GSNTDELAQLVTVLMKEVTTEEELNALRMFMRTDLQNLPGFEI-AFRRILELGEDNISWHNRQYH 892
            ...:..:|.:|.....:.:|...|..::.|..:..:|  |.:: ..::.:|..|:||.|.::.:.
  Rat   878 ELGSSSIAHMVMGTTNQFSTRARLEEVKGFFSSLKKN--GSQLRCVQQTIETIEENIRWMDKNFD 940

  Fly   893 NL 894
            .:
  Rat   941 KI 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	ERAP1_C	561..878	CDD:288671	74/331 (22%)
		Peptidase_M1	25..392	CDD:279741	100/409 (24%)
		GluZincin	30..480	CDD:301352	124/517 (24%)
Erap1	XP_006231762.1	Peptidase_M1	42..454	CDD:279741	109/452 (24%)
		M1_APN_2	50..544	CDD:189008	127/536 (24%)
		ERAP1_C	611..927	CDD:288671	74/332 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850