Protein Alignment CG9806 and Aopep

DIOPT Version :9

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 613
• Identity: 119/613 - (19%)
• Similarity: 200/613 - (32%)
• Gaps: 176/613 - (28%)

  Fly   129 SRASGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRV 193
            ::..|..|....|....|  ...|..:|.....:|||.|      |.:..........|.::..|
Mouse   250 TKPEGQSVAWTTDQNGRP--CVYTMGSPINNRALFPCQE------PPVAMSTWQATVRAAASFVV 306

  Fly   194 LKTSDHE------KDDYVWTTFQQTPAMSVQKLAFSINRFTNRTSAEIPKGPALTTWLRPKIADQ 252
            |.:.::.      ::.|:...:..|..|.....|.::..:|.......|....:|....|....:
Mouse   307 LMSGENSAKPTPLREGYMSWHYYVTMPMPASTFAIAVGCWTEMKPKASPPDDLMTEHSLPLSPSE 371

  Fly   253 GDY-----------------AISITPQIIVFFI--------------------------SLFGKP 274
            .|.                 |.:.:..||.:.:                          |:.| .
Mouse   372 ADLRYDNTCNHMEYPCRFQSASAASQDIIPYRVFAPVCLEGACQEALLWLIPSCLSAAHSVLG-T 435

  Fly   275 YPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQQVASHVAQEFAHHWLSDLEN 339
            :|..::|.|::| |.:.|   ||:.| |...||  :|.:.|.......:.:..|.||.|.. |..
Mouse   436 HPFSRLDILIVP-TNFPS---LGMAS-PHIIFL--SQSTLTGTSHLCGTRLCHEIAHSWFG-LAI 492

  Fly   340 AALYWLHNGLSDYVSGFAVDNVEPAW---------------------RFH----ELSMVRQALAV 379
            .|..|....||:   |||....:..|                     |:|    ||....:.:.|
Mouse   493 GARDWTEEWLSE---GFATHLEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELRNSPEGMQV 554

  Fly   380 LVEDSKSSAYPMSLAYAS--------KSSDTQANQ-KSALLFRMLHSLIGTQAFLNALRLYLQRS 435
            |..:.:.:.: :|.:.||        :....|.:. |...|.|.|...:|.:.:...||.::...
Mouse   555 LRPNKEETGH-VSASGASVVKHGLNPEKGFMQVHYLKGYFLLRFLTRTLGEKIYFPFLRKFVHLF 618

  Fly   436 HKGSSSNQAFLWHTLQEESDNQMSLRQDIKVSQLMDSWTMQPGYP----------------LIRV 484
            |.....:|.||...|:...:|:   |..:.|..::..|....|.|                |.|.
Mouse   619 HGQLILSQDFLQMLLENIPENK---RLGLSVENIVRDWLECSGIPKALQEERKAEDCSPSRLARQ 680

  Fly   485 VRNYDTNEVTVTQERFLRNPGKLMQKRQQCWWVPLTFATAGIDSFVSTLPSEWLTCQGRQTASPL 549
            |.:.....:.|.     |.|.|..:.:::     :.|.....|..|..|  |||..|  :|.||.
Mouse   681 VGSEVAKWIRVN-----RRPRKRKRGKRE-----VAFEKLSPDQIVLLL--EWLLEQ--KTLSPQ 731

  Fly   550 ILNEVAQ----PD-------KWVVFNLRLATPCRITYDERNWQLIGNALSGTNA-SSIDRFTRAQ 602
            .|:.:.|    |:       :|          |.:....:.          |.| :.::||
Mouse   732 TLHCLQQTYHLPEQDAEVRHRW----------CELVIKHKY----------TKAYNQVERF---- 772

  Fly   603 LISDV---LNLAGAGVVTYDLALNFLGH 627
            |:.|.   :.|.|..:|:.|..|..|.|
Mouse   773 LLEDQAMGIYLYGELMVSEDARLQQLAH 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	ERAP1_C	561..878	CDD:288671	14/71 (20%)
		Peptidase_M1	25..392	CDD:279741	61/336 (18%)
		GluZincin	30..480	CDD:301352	82/433 (19%)
Aopep	NP_001276853.1	GluZincin	186..634	CDD:301352	76/404 (19%)
		Leuk-A4-hydro_C	680..821	CDD:286244	34/159 (21%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703		3/9 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845878
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830