Protein Alignment CG9806 and RNPEP

DIOPT Version :10

• Sequence 1: NP_572643.1
• Gene: CG9806 / 31994
• FlyBaseID: FBgn0030222
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_064601.3
• Gene: RNPEP / 6051
• HGNCID: 10078
• Length: 650
• Species: Homo sapiens
• Alignment Length: 680
• Identity: 140/680 - (20%)
• Similarity: 210/680 - (30%)
• Gaps: 207/680 - (30%)

  Fly    22 ATASNLRP---LHYNLSLLTEVEPL---KLSGNFSGEVIIRLRVWRETRTIIL---SNNGLQVGE 77
            |:|||.|.   ||.:|.|..|..|.   ..|...||..::.||.........|   |:..|:|
Human    26 ASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEV-- 88

  Fly    78 NVLLVRRNTGGR-----------------------VTVRKMWQASSVHQLGIVFN-----SMLWL 114
            ....:||...|.                       |:..:..:|:...|:.:.:.     .:.||
Human    89 TAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWL 153

  Fly   115 GEEYTLVVQFSGQLSRASGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNL 179
            ..|.|.                     .|..|  ...||....|....||||:.......:...:
Human   154 APEQTA---------------------GKKKP--FVYTQGQAVLNRAFFPCFDTPAVKYKYSALI 195

  Fly   180 AHPRGTNAVSNMRVLKTSDHEKDDYVWTTFQQTPAMSVQKLAFSINRFTNRTSAEIPKGPALTTW 244
            ..|.|..|     |:..|..||.......||....:....:|.:|.   :..|||:  ||....|
Human   196 EVPDGFTA-----VMSASTWEKRGPNKFFFQMCQPIPSYLIALAIG---DLVSAEV--GPRSRVW 250

  Fly   245 LRPKIAD--QGDYAISITPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFL 307
            ..|.:.|  :.:|. .:..:.:.....||| ||...:.|.|.:|.:.     ..|.:..|...|:
Human   251 AEPCLIDAAKEEYN-GVIEEFLATGEKLFG-PYVWGRYDLLFMPPSF-----PFGGMENPCLTFV 308

  Fly   308 YSAQRSTTRAKQQVASHVAQEFAHHWLSDL---ENAALYWLHNGLSDYVS--------GFAVDNV 361
            .....:..|:...|..|   |.:|.|..:|   .|...:||:.|.:.|..        |.|...:
Human   309 TPCLLAGDRSLADVIIH---EISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCL 370

  Fly   362 EPAWRFHELSMVRQALAVLVEDSKSSAYPMSLAYASKSSDTQAN---QKSALLFRMLHSLIGTQ- 422
            |.|   ...:::||.:.:..|::..:...:.:.......||...   :|.......|..|:|.|
Human   371 EAA---TGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQD 432

  Fly   423 ---AFLNA---------------LRLYLQ------------------------------------ 433
               :||.|               |..||:
Human   433 QFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSP 497

  Fly   434 -RSHKGSSSNQAFLWHTLQEESDNQMSLRQDIKVS------------QLMDSWTMQPG------- 478
             .|....:...|.||  ..||.|  |...:.:.:|            :::....:.||
Human   498 GDSLMKPAEELAQLW--AAEELD--MKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGD 558

  Fly   479 -YPLIRVVRN-------------YDTNEVTVTQERFLRNPGKLMQKRQQCWWVPLTFATAGIDSF 529
             ||.|...||             .|..|.....:.||.|.||      |.:.:||..|..|....
Human   559 TYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGK------QKYTLPLYHAMMGGSEV 617

  Fly   530 VSTLPSEWLTCQGRQTASPL---ILNEVAQ 556
            ..||..|...    .|||.|   ::|.|.|
Human   618 AQTLAKETFA----STASQLHSNVVNYVQQ 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	M1_APN-Q_like	30..474	CDD:341064	106/561 (19%)
		ERAP1_C	560..878	CDD:463368
RNPEP	NP_064601.3	M1_LTA4H	24..484	CDD:341062	102/505 (20%)
		Leuk-A4-hydro_C	530..644	CDD:462686	29/124 (23%)