DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9806 and CG10602

DIOPT Version :9

Sequence 1:	NP_572643.1	Gene:	CG9806 / 31994	FlyBaseID:	FBgn0030222	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_609916.5	Gene:	CG10602 / 35146	FlyBaseID:	FBgn0032721	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	563	Identity:	119/563 - (21%)
Similarity:	188/563 - (33%)	Gaps:	164/563 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 TASNLRPLHY----NLSLLTEVEPLKLS--------------------GNFSGEVIIRLRVWR-- 61
            |:..|.|::.    |:..|..|:|...|                    ....|.|:.|.:|..
  Fly    57 TSHKLLPIYQVQKRNMGRLGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTAN 121

  Fly    62 ------ETRTIILSNNGLQVGENVL--------------------LVRRNTGGRVTVRKMWQASS 100
                  :.|.|.::|..|..|.:.|                    |......|.:.||..::.||
  Fly   122 LDKILLDVRDINVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSS 186

  Fly   101 VHQLGIVFNSMLWLGEEYTLVVQFSGQLSRASGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPC 165
                  ..:.:.||....||                     .|.||...:..|...  |.:|.||
  Fly   187 ------SASGLQWLNPTQTL---------------------GKEHPYMFSQCQAIH--ARSVIPC 222

  Fly   166 FENRTFLAPFILNLAHPRGTNAVSNMRVLKTSDHEKDDYVWTTFQQTPAMSVQKLAFSINRFTNR 230
            .:.......:...:.||      |.:..|.::..:|.:...|.|:|...:....:|.:|.:..:|
  Fly   223 QDTPAVKFTYDATVEHP------SELTALMSALIDKKEPGKTLFKQEVPIPAYLVAIAIGKLVSR 281

  Fly   231 TSAEIPKGPALTTWLRPKIADQGDYAISITPQIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEH 295
                 |.|...:.|....|.|......|.|..::.....|.| ||...:.|.||:|.
  Fly   282 -----PLGENSSVWAEEAIVDACAEEFSETATMLKTATELCG-PYVWKQYDLLVMPP-------- 332

  Fly   296 LGLVSYP----EAAFLYSAQRSTTRAKQQVASHVAQEFAHHWLSDL---ENAALYWLHNGLSDYV 353
                |:|    |...|.....:.....:.:|..||.|.||.|..:|   :|...:||:.|.:.:|
  Fly   333 ----SFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFV 393

  Fly   354 SGFAVDNVEPAWR--FHELS-------MVRQALAVLVEDSK-----SSAYP----MSLAYASKSS 400
            ....|..::.|..  |..||       .:|..|....|.:|     |:..|    .|:.|.
  Fly   394 ESKIVGRMQGAKELDFKMLSNLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYI---- 454

  Fly   401 DTQANQKSALLFRMLHSLI-GTQAFLNALRLYLQRSHKGSSSNQAFLWHTLQEESDNQMSL---- 460
                  |.:...|.|..|. |...|...||.||::          :.:.:: |..|.|.:|
  Fly   455 ------KGSTFLRYLEDLFGGPTVFEPFLRDYLKK----------YAYKSI-ETKDFQSALYDYF 502

  Fly   461 ----RQDIKVSQL-MDSWTMQPGYPLIRVVRNYDTNEVTVTQE 498
                ::| |:|.: .|.|....|.|  .|:.|:|.:...||:|
  Fly   503 IDTDKKD-KLSAVDWDLWLKSEGMP--PVIPNFDESLANVTKE 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	ERAP1_C	561..878	CDD:288671
		Peptidase_M1	25..392	CDD:279741	89/443 (20%)
		GluZincin	30..480	CDD:301352	109/536 (20%)
CG10602	NP_609916.5	Ribosomal_L13	16..>50	CDD:294238
		leuko_A4_hydro	79..681	CDD:274120	113/541 (21%)
		M1_LTA4H	79..520	CDD:189006	104/515 (20%)
		Leuk-A4-hydro_C	541..680	CDD:286244	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462063
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840