DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9806 and Rnpepl1

DIOPT Version :9

Sequence 1:	NP_572643.1	Gene:	CG9806 / 31994	FlyBaseID:	FBgn0030222	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_852070.3	Gene:	Rnpepl1 / 108657	MGIID:	1914170	Length:	720	Species:	Mus musculus

Alignment Length:	418	Identity:	94/418 - (22%)
Similarity:	146/418 - (34%)	Gaps:	98/418 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 FPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKTSD-----HEKDDYVWTTFQQTPAMSVQKLAF 222
            ||||:.......:...:..|.|      ::||.::.     .|:..|.:......||..|..:|.
Mouse   201 FPCFDTPAVKCTYSAVVKAPLG------VQVLMSATQSVYVEEEGLYHFHMEHPVPAYLVALVAG 259

  Fly   223 SINRFTNRTSAEIPKGPALTTWLRPKIADQGDYAIS-ITPQIIVFFISLFGKPYPAMKIDQLVLP 286
            .:.      .|:|  ||....|..|.:.......:| ...|.:.....|:| ||...:.|.:.||
Mouse   260 DLK------PADI--GPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYG-PYMWGRYDIVFLP 315

  Fly   287 DTAYQSHEHLGLVSYPEAA-------FLYSAQRSTTRAKQQVASHVAQEFAHHWLSDLENAALY- 343
            .            |:|..|       |:.|   |...:.:.:...|..|.||.|..:....|.:
Mouse   316 P------------SFPIVAMENPCLTFIIS---SILESDEFLVIDVIHEVAHSWFGNAVTNATWE 365

  Fly   344 --WLHNGLSDYVS--------GFAVDNVEPAWRFHELSMVRQALAVLVEDSKSSAYPMSLAYASK 398
              ||..||:.|..        |.|...:|.|:|   |..:.:.:.:|.|||..|...:.|.....
Mouse   366 EMWLSEGLATYAQRRITTETYGAAFTCLETAFR---LDALHRQMRLLGEDSPVSKLQVKLEPGVN 427

  Fly   399 SSDTQ---ANQKSALLFRMLHSLI-GTQAFLNALRLYLQRSHKGSSSNQAFLWHTLQEESDNQMS 459
            .|...   ..:|.......|..|. |.|.|.:.||.|::: :|.:|.       ..|:..|:.:|
Mouse   428 PSHLMNLFTYEKGYCFVYYLSQLCGGPQRFDDFLRAYVEK-YKFTSV-------VAQDLLDSFLS 484

  Fly   460 LRQDIKVSQL-------MDSWTMQPGYPLIRVVRNYDTNEVTVTQERFLRNPGKLMQKRQQCWWV 517
            ...::|...:       .:.|....|.||.         |..::|...|..|   ::...|.|..
Mouse   485 FFPELKEQSVDCRAGLEFERWLNATGPPLA---------EPDLSQGSSLTRP---VEALFQLWTA 537

  Fly   518 -PLTFATA---GIDSFVSTLPSEWLTCQ 541
             ||..|.|   .||.      |:|.|.|
Mouse   538 EPLEQAAASASAIDI------SKWRTFQ 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	ERAP1_C	561..878	CDD:288671
		Peptidase_M1	25..392	CDD:279741	57/252 (23%)
		GluZincin	30..480	CDD:301352	76/351 (22%)
Rnpepl1	NP_852070.3	M1_LTA4H	29..507	CDD:189006	75/346 (22%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P15144	321..325		1/3 (33%)
		Leuk-A4-hydro_C	524..668	CDD:312599	14/45 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	671..708
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830