DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9806 and lnpep

DIOPT Version :9

Sequence 1:	NP_572643.1	Gene:	CG9806 / 31994	FlyBaseID:	FBgn0030222	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	XP_002933474.1	Gene:	lnpep / 100216271	XenbaseID:	XB-GENE-950921	Length:	1024	Species:	Xenopus tropicalis

Alignment Length:	883	Identity:	219/883 - (24%)
Similarity:	389/883 - (44%)	Gaps:	77/883 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LHLCLPIGGTGAT--------ASNLRPLHYNLSLLTEVEPLKLSGNFSGEVIIRLRVWRETRTII 67
            |.|..||...|..        .::::|:||.|:|    .|...:..|:|.|.|:|.:...:..|:
Frog   147 LELVYPIATNGKVFPWAKSRLPNSIKPVHYVLTL----HPDMTTMYFAGTVQIKLNITASSNNIV 207

  Fly    68 LSNNGLQVGENVLLVRRNTGGRVTVRKMWQASSVHQLGIVFNSMLWLGEEYTLVVQFSGQLSRA- 131
            |.::||::.:..:.|   |.|.....::.:..:..::.|:....|..|:|..|.:|::...|..
Frog   208 LHSSGLRIIKAHVSV---TEGTTMDAEVLEYPTFEEIAIILPESLPKGKECLLTIQYTSNFSSTY 269

  Fly   132 SGYFVGGYMDSKHHPQWIAVTQLAPNLANTVFPCFENRTFLAPFILNLAHPRGTNAVSNMRVLKT 196
            .|::...||: |.:.:.:|.||..|..|..|||||:...|.:.|.:|:...:...::|||...||
Frog   270 YGFYKIDYME-KGNKRSLAATQFEPLAARKVFPCFDEPAFKSTFQINIIRNQSMISLSNMPKAKT 333

  Fly   197 SDHEKDDYVWTTFQQTPAMSVQKLAFSINRFTNRTSAEIPKGPALTTWLRPKIADQGDYAISITP 261
            |. ..|..:...:..:..||...:||.:....|.|  :......::.:..|:..||..||:....
Frog   334 ST-MSDGLLLDEYSTSVNMSTYLVAFIVGDIKNTT--QETNDTLVSVYAVPEKMDQVKYALDSAM 395

  Fly   262 QIIVFFISLFGKPYPAMKIDQLVLPDTAYQSHEHLGLVSYPEAAFLYSAQRSTTRAKQQVASHVA 326
            :::.|:.:.:...||..|:|.:.:||....:.|:.||:::.|.|.||....|:...||.:...:|
Frog   396 KLLYFYSNYYNIAYPLKKLDLVAIPDFQAGAMENWGLITFRETALLYKEDSSSVADKQSITKVIA 460

  Fly   327 QEFAHHWLSDLENAALY---WLHNGLSDYVSGFAVDNVEPAWRFHELSMVRQALAVLVEDSKSSA 388
            .|.||.|..:|.....:   ||:.|.:.|:...::.::.|... .|.|.::.....|.:||.:::
Frog   461 HELAHQWFGNLVTMEWWNDLWLNEGFATYMEYVSMSSLFPELN-SENSFLKMRFTALQKDSLNAS 524

  Fly   389 YPMSLAYASKSS-----DTQANQKSALLFRMLHSLIGTQAFLNALRLYLQRSHKGSSSNQAFLWH 448
            :|:|....|...     |..:..|.|.:..||.:.:....|.:.:..|||....||:::.: ||.
Frog   525 HPISTDIQSPEQIEEMFDDLSYIKGASILLMLQAFLSEDVFHHCIMEYLQAHQYGSTTSDS-LWD 588

  Fly   449 TLQEESDNQMSLRQDIKVSQLMDSWTMQPGYPLIRVVRNYDTNEVTVTQERFLRNPG-KLMQKRQ 512
            ::      .:...::..|..:|.:||.:.||||:..:|..:  |:||.||||||.|. .......
Frog   589 SM------NVVTNKNPNVKNMMKTWTQKAGYPLVTALRKGE--EITVQQERFLRTPSPDHATNAS 645

  Fly   513 QCWWVPLTFATAGIDSFVSTLPSEWLTCQG--RQTASPLILNE------VAQPDKWVVFNLRLAT 569
            ..|.:|||:.|.              .|.|  .|..:..:|.|      |:....||.||:.:..
Frog   646 TVWHIPLTYVTR--------------KCSGIEPQCDNIYLLKEVTGRINVSSEFPWVKFNVNMTG 696

  Fly   570 PCRITYDERNWQLIGNAL--SGTNASSIDRFTRAQLISDVLNLAGAGVVTYDLALNFLGHLRNE- 631
            ...:.|....|..:...|  ..|...|.|   ||.||.|:..|||.|.|....|...||:|.||
Frog   697 YYIVDYGADGWDALIKQLLRDHTVLHSSD---RANLIHDIFMLAGVGKVPLAKAFELLGYLANET 758

  Fly   632 DEFIVWQAADTYLEWLHRTLRQTTIISTFKGFMR---DLLQTKFDELFKRDGSAAENANITELMV 693
            :...:.||.:.:.. :|..|.:..:.......|.   .||....::.::.:|:.||.    ||..
Frog   759 NSAPITQALNQFYH-IHGILLKRGLDELSDKVMERGLKLLSNLINQTWEDEGTLAER----ELRS 818

  Fly   694 IVLQLSCRTDLESCADFALKEFAGLTLETNRIPVDLSETIYCTAIQFGTEADWTLLRRLYTRSNV 758
            .:|..:|.:.|:||.|.|::.|....|...|||.|:.:.::....:  |...|..|...||.|..
Frog   819 SLLDFACSSGLQSCVDKAMELFNIWRLNNTRIPTDVMKVVFKVGAK--TAEGWAFLWDKYTTSLY 881

  Fly   759 SEERRILLSAMACSRENWALDKLLNLAFAGRYMPKDDVLLIFSAVAQNPLGYNIAKKYLVDNIKA 823
            ..|:|.:|.|:|.:.....|..|:..:..|..:...::..:...:::...||.:|.::...|...
Frog   882 ETEKRKILEALASTDNGRKLQWLMQESLDGGLIRSQELPAVLGFISKGSPGYLLAWEFAKQNWDL 946

  Fly   824 IIKLYGSNTDELAQLVTVLMKEVTTEEELNALRMFMRT 861
            |.:.:...:..:..:|:......:|:..||.:..|..:
Frog   947 ITQKFMPGSFPIQSIVSTTTYHFSTDTHLNEVIAFFNS 984

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9806	NP_572643.1	ERAP1_C	561..878	CDD:288671	74/307 (24%)
		Peptidase_M1	25..392	CDD:279741	94/370 (25%)
		GluZincin	30..480	CDD:301352	113/458 (25%)
lnpep	XP_002933474.1	M1_APN-Q_like	174..609	CDD:341064	111/453 (25%)
lnpep	XP_002933474.1	ERAP1_C	687..1003	CDD:378732	75/308 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020