Protein Alignment Rab9Db and RAB9A

DIOPT Version :10

• Sequence 1: NP_572642.1
• Gene: Rab9Db / 31993
• FlyBaseID: FBgn0030221
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 184
• Identity: 58/184 - (31%)
• Similarity: 89/184 - (48%)
• Gaps: 34/184 - (18%)

  Fly     8 FKIIILGDSGVGKTCLLMRFSDNQFTERHRVTVGMD--RRECSVEFADWRMGRM--LQVWDTSDD 68
            ||:|:|||.||||:.|:.|:..|:|..:...|:|::  .::..|:      |..  :|:|||:..
Human     8 FKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVD------GHFVTMQIWDTAGQ 66

  Fly    69 ERFKLLKATQCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLC----PDKVTVLLVGNKSDDPNH 129
            |||:.|:....|.:...||.:.:..|:||||:..|.||.....    |:....:::|||. |.:.
Human    67 ERFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKI-DISE 130

  Fly   130 RQVSMAQGFNYAHRQSIC-------FEEVSAKSGRNVYDIFSSLAMDIYTYRRV 176
            ||||..:.      |:.|       :.|.|||...||...|..      ..|||
Human   131 RQVSTEEA------QAWCRDNGDYPYFETSAKDATNVAAAFEE------AVRRV 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Db	NP_572642.1	Rab	8..167	CDD:206640	55/173 (32%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	56/182 (31%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		2/10 (20%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		4/13 (31%)