Protein Alignment Rab9Db and RAB35

DIOPT Version :10

• Sequence 1: NP_572642.1
• Gene: Rab9Db / 31993
• FlyBaseID: FBgn0030221
• Length: 197
• Species: Drosophila melanogaster
• Sequence 2: NP_006852.1
• Gene: RAB35 / 11021
• HGNCID: 9774
• Length: 201
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 68/163 - (41%)
• Similarity: 107/163 - (65%)
• Gaps: 3/163 - (1%)

  Fly     4 YDNPFKIIILGDSGVGKTCLLMRFSDNQFTERHRVTVGMDRRECSVEFADWRMGRMLQVWDTSDD 68
            ||:.||::|:|||||||:.||:||:||.|:..:..|:|:|.:..:||....::  .||:|||:..
Human     5 YDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKV--KLQIWDTAGQ 67

  Fly    69 ERFKLLKATQCRSAHGILLVYDITSSKSFQNIDGWMKEIRRLCPDKVTVLLVGNKSDDPNHRQVS 133
            |||:.:.:|..|..||:::|||:||::||.|:..|:.||.:.| |.|..:|||||:|||..:.|.
Human    68 ERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPERKVVE 131

  Fly   134 MAQGFNYAHRQSICFEEVSAKSGRNVYDIFSSL 166
            ....:.:|.:..|...|.|||...||.::|:.:
Human   132 TEDAYKFAGQMGIQLFETSAKENVNVEEMFNCI 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab9Db	NP_572642.1	Rab	8..167	CDD:206640	66/159 (42%)
RAB35	NP_006852.1	Rab35	3..201	CDD:133310	68/163 (42%)
		Switch 1. /evidence=ECO:0000269|PubMed:30905672, ECO:0007744|PDB:6IF2, ECO:0007744|PDB:6IF3	30..42		4/11 (36%)
		Switch 2. /evidence=ECO:0000269|PubMed:30905672, ECO:0007744|PDB:6IF2, ECO:0007744|PDB:6IF3	64..80		5/15 (33%)