DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43347 and znf1043

DIOPT Version :9

Sequence 1:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster
Sequence 2:	XP_009299198.1	Gene:	znf1043 / 565722	ZFINID:	ZDB-GENE-080215-14	Length:	476	Species:	Danio rerio

Alignment Length:	398	Identity:	93/398 - (23%)
Similarity:	148/398 - (37%)	Gaps:	93/398 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly  1133 SCRDLRNGMELLYWSDDCNTMWRKKHTEKT--NCGGCNLKFEHPLYYRTHCSVFHDPSMSLTIRK 1195
            ||:..||........|    :..:.||.:.  .|..|...|.....::.|..:.....      |
Zfish    83 SCKQCRNSFSQKSKLD----VHMRVHTREQPYTCEQCGKSFGQIQGFKAHMRIHTGEG------K 137

  Fly  1196 YHCKVCGEPVLGKDNIMKHAAEKHDGKGAYQCQFCSKFFLRLNYLEMH-RTYGCASNPNRSRP-V 1258
            :.|:.||:......|...| ...|.|:..:.|:.|.|.|.:.:.|::| |.:      .|.:| .
Zfish   138 FTCQECGKSFYQAGNFAAH-MRIHTGEKPFSCKQCGKSFSQKSNLDVHMRVH------TREQPYT 195

  Fly  1259 CDFCGRKFCQPQKLKAHIKRMHS------------------DMAEVLR------DFQCKLCSKLL 1299
            |:.||:.|.|.|..|||: |:|:                  :.|..:|      .|.||.|.|..
Zfish   196 CEQCGKSFGQIQSFKAHM-RIHTGEGKFTCQECGKSFYQAGNFAAHMRIHTGEKPFSCKQCGKSF 259

  Fly  1300 GSRAALQRHSKEVHSRNSTVVSCPRCQKLFQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQC 1364
            ..::.|..|.: ||:|... .:|.:|.|.|..:.:...||..|:|.:||.|  .:|..:|..|..
Zfish   260 SQKSNLDVHMR-VHTREQP-YTCEQCGKSFSQKQSFNTHMRIHTGEKPFSC--KQCGKSFFQKPN 320

  Fly  1365 LQFHYKKVHN----YTQEQMPKIERSVAYTFDAYSGGMKVDF-------LGKQTATATPASAA-- 1416
            |..| .:||.    :|.||..|            |.|.|.|.       .|::..|.|....:
Zfish   321 LDVH-MRVHTGEKPHTCEQCGK------------SFGQKQDLYIHMRIHTGEKPYTCTECGKSFP 372

  Fly  1417 ---------SAQAQPRPNAAVVSPSSFTEQAPRRRRKSLEDQSSMLSGSLQSDAEFSDDNLF--E 1470
                     ......:|.|......|||      .:.||::..:..:|::....:....:|.  :
Zfish   373 HISTLKHHMRIHTGEKPFACAQCGKSFT------TKTSLKNHMNGHTGTIVFTCDQCGKSLTRKD 431

  Fly  1471 AIKKSGKS 1478
            .|||..|:
Zfish   432 TIKKHMKT 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	20/71 (28%)
		C2H2 Zn finger	1198..1219	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1227..1255	CDD:275368	7/28 (25%)
		C2H2 Zn finger	1259..1280	CDD:275368	10/20 (50%)
		C2H2 Zn finger	1292..1313	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1322..1342	CDD:275368	6/19 (32%)
		zf-H2C2_2	1334..1361	CDD:290200	9/26 (35%)
		C2H2 Zn finger	1350..1373	CDD:275368	6/22 (27%)
znf1043	XP_009299198.1	COG5048	67..468	CDD:227381	93/398 (23%)
		C2H2 Zn finger	84..104	CDD:275368	4/23 (17%)
		C2H2 Zn finger	112..132	CDD:275368	4/19 (21%)
		C2H2 Zn finger	140..160	CDD:275368	5/20 (25%)
		zf-H2C2_2	152..177	CDD:290200	8/25 (32%)
		C2H2 Zn finger	168..188	CDD:275368	7/19 (37%)
		zf-H2C2_2	180..203	CDD:290200	8/28 (29%)
		C2H2 Zn finger	196..216	CDD:275368	10/20 (50%)
		C2H2 Zn finger	224..244	CDD:275368	2/19 (11%)
		zf-H2C2_2	236..261	CDD:290200	7/24 (29%)
		C2H2 Zn finger	252..272	CDD:275368	6/20 (30%)
		zf-H2C2_2	264..289	CDD:290200	9/26 (35%)
		C2H2 Zn finger	280..300	CDD:275368	6/19 (32%)
		zf-H2C2_2	292..315	CDD:290200	8/24 (33%)
		C2H2 Zn finger	308..328	CDD:275368	6/22 (27%)
		zf-H2C2_2	320..343	CDD:290200	8/35 (23%)
		C2H2 Zn finger	336..356	CDD:275368	7/31 (23%)
		zf-H2C2_2	348..371	CDD:290200	4/22 (18%)
		C2H2 Zn finger	364..384	CDD:275368	1/19 (5%)
		zf-H2C2_2	377..401	CDD:290200	5/29 (17%)
		C2H2 Zn finger	392..412	CDD:275368	5/25 (20%)
		C2H2 Zn finger	420..440	CDD:275368	5/20 (25%)
		C2H2 Zn finger	448..468	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910