DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43347 and zf30C

DIOPT Version :9

Sequence 1:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster
Sequence 2:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster

Alignment Length:	648	Identity:	132/648 - (20%)
Similarity:	215/648 - (33%)	Gaps:	219/648 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   814 EEEDEDEDQPPHPHLLPVLPPADAVDGITASNGQAGNFHVRSKSQGSKKSQAAKAAAAAMMPPNS 878
            |.||.|:|.|                  .||         |.|::..::||.:          :|
  Fly   196 ESEDSDDDIP------------------LAS---------RLKTKLKQESQNS----------DS 223

  Fly   879 YDEHDD-EPGAGLGGNDEDDDDDE--ELDEEALAREMKMEQNFVEEEDEHDIAFRSHQSCRECSI 940
            .||..| ||     .|.|||.|..  :|...|:.:        ||..||.|..::......:
  Fly   224 GDECPDFEP-----NNSEDDADASGFQLPPPAMVK--------VEAFDEEDFEYQDASMYVK--- 272

  Fly   941 AHDHKLCPLRNACGNVTDAVDLGEWIERRNLEALAKLKADAQRQAKRASGRQRHEDDDMEDMEDM 1005
                            |::.|:....:.:.|:.|.                  :|.|.::..|.:
  Fly   273 ----------------TESTDIFSNEKDKLLDVLL------------------NEGDGLKPFESL 303

  Fly  1006 DMDMDESSQLSELETKPLITFAEASVPAEFELHNVE----PNVTGVFARTEVRAFTKLGPLIGQP 1066
            .::.. :..|.|:...||:..||..| .|...|.:|    |...|...:.::            |
  Fly   304 KVEQG-AGILDEIAAVPLVEVAEEDV-LELRGHQMEKPPGPRKRGRPPKEKI------------P 354

  Fly  1067 VQTGEVREGSDMKWIFEMCEAGADKSYLLCCDNPNASNWLRFVRPAPSYEERNVNLVSIDRQAYF 1131
            |...:.|:                                |....:||.::.:    ...::...
  Fly   355 VVKRKYRK--------------------------------RNAPRSPSPDDSS----GTPKRVAK 383

  Fly  1132 VSCRDLR------NGMELLYWSDDCNTMWR-KKHTEKTNCGGCNLKFEHPLYYRTHCSVFHDPSM 1189
            :|.::|:      |.||..:....|..::. :|..||      :|:.:|.|.......:|.|..:
  Fly   384 ISKKELKERLKMINKMEKSWKCPHCVKIYHIRKPYEK------HLRDDHKLNEAEMKEIFKDVDV 442

  Fly  1190 --SLTIRKYHCKVCGEPVLGKDNIMKH-AAEKHDGKGAYQCQ-FCSKFFL--------------R 1236
              .|....:.|.:|.:..|.:..::.| .....|||..::|. :|:.||.              .
  Fly   443 HAKLDEEVFKCPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKE 507

  Fly  1237 LNYLEMHRTY--GCASNPNRSRP--------------VCDFCGRKFCQPQKLKAHIKR------- 1278
            |.|.|....|  |..|..|..|.              :||.||:||.....|..|::.
  Fly   508 LLYCEKCDKYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPL 572

  Fly  1279 -------MHSDMAEVLR----------DFQCKLCSKLLGSRAALQRHSKEVHSRNSTVVSCPRCQ 1326
                   .|...|.:|:          .:||..|.|....:|..:.|.|..|: :.....|..|.
  Fly   573 YGCSVCGKHLSTAGILKTHMLLHKADTPYQCDKCGKTFKVKAQYKSHLKTRHT-DYKPYKCHLCP 636

  Fly  1327 KLFQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQCLQFHYKKVHNYTQEQMPKIERSVAY 1389
            |.:..|.:|..||..|:|::.|.|  ..|...||....||.| :|||..|..|:|...::..|
  Fly   637 KEYPYRESLLTHMTVHTGIKRFLC--NNCGKRFTCISNLQAH-RKVHADTCGQLPLNAKATQY 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	25/101 (25%)
		C2H2 Zn finger	1198..1219	CDD:275368	4/21 (19%)
		C2H2 Zn finger	1227..1255	CDD:275368	11/44 (25%)
		C2H2 Zn finger	1259..1280	CDD:275368	8/34 (24%)
		C2H2 Zn finger	1292..1313	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1322..1342	CDD:275368	7/19 (37%)
		zf-H2C2_2	1334..1361	CDD:290200	9/26 (35%)
		C2H2 Zn finger	1350..1373	CDD:275368	8/22 (36%)
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368
		C2H2 Zn finger	134..152	CDD:275368
		C2H2 Zn finger	511..532	CDD:275370	6/20 (30%)
		COG5048	<523..>672	CDD:227381	36/151 (24%)
		C2H2 Zn finger	546..566	CDD:275368	8/19 (42%)
		C2H2 Zn finger	575..595	CDD:275368	3/19 (16%)
		C2H2 Zn finger	603..624	CDD:275368	6/20 (30%)
		C2H2 Zn finger	632..652	CDD:275368	7/19 (37%)
		C2H2 Zn finger	660..680	CDD:275368	8/22 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100