DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43347 and CG3032

DIOPT Version :9

Sequence 1:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster
Sequence 2:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	435	Identity:	96/435 - (22%)
Similarity:	159/435 - (36%)	Gaps:	99/435 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  1015 LSELETKPLITFAEA-SVPAEFEL---------HNVE---------PNVTGVFARTEVRAFTKLG 1060
            |.:||.:||.|..:: .:|...||         .:||         ||...:..|:.|:.|.|..
  Fly    18 LLQLEKEPLKTELQSDEIPISQELQQLLNINLSQDVENQDADQQWLPNELCLECRSAVQNFEKFR 82

  Fly  1061 PLIGQ-PVQTGEVREGSDMKWIFEMCEAGADKSYLLCCDNPNASNWLRFVRPAPSYE-------- 1116
            ....: ..|..|:.:....:..||:...|.:       ::..:.:.|....|||..:
  Fly    83 RKADECRKQLLEMLKKDPREPTFEVVYDGRE-------EDQESLHGLEPPEPAPDPDPIDEPAIK 140

  Fly  1117 -----------ERNVNLVSIDRQAY------FVSCRDLRNGMELLYWSDDCN----------TMW 1154
                       .||....|:.|:::      ....|.:..|.:..:..|.|.          |..
  Fly   141 SDKSPRKSFRGSRNTLKCSVCRRSFAHQITLAAHIRKVHEGSKRPFQCDQCEKAYSFMGGLYTHI 205

  Fly  1155 RKKHTEKTN---CG--GCNLKFEHPLYYRTHCSVFHDPSMSLTIRKYHCKVCGEPVLGKDNIMKH 1214
            |:.|..|..   |.  ||...:...:..:.|..:.|.|.....::|:.|:.||.......|:..|
  Fly   206 REVHAPKERRHPCDQPGCERIYTSRIAMQKHKRLKHSPRDRDALKKFICEQCGASFNQSANLKYH 270

  Fly  1215 AAEKHDGK--------GAYQCQFC--------SKFFLRLNYLEMHRTYGCASNPNRSRPVCDFCG 1263
            ...||..:        ||.:..||        |::.|:.:.|:.|...  ...|:.    |..||
  Fly   271 LKTKHPTEDEVAAREGGAGERHFCDICQKEFHSRYTLKYHTLQQHEVQ--EELPHE----CQVCG 329

  Fly  1264 RKFCQPQKLKAHIKRMHSDMAEVLRDFQCKLCSKLLGSRAALQRHSKEVHSRNSTVVSCPRCQKL 1328
            |:..:...|..|: .|||:     ....|:.|.:....|..|:.|.:.||.:... ..|..|.:.
  Fly   330 RRMAKKFMLLQHM-LMHSN-----DKLPCEHCGRRFARRFELEAHVRAVHLKLKP-FPCHHCPES 387

  Fly  1329 FQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQCLQFHYKKVH 1373
            |.:|..|:.|...|:|.:|:.|  ..|..||..:.||:.| :|||
  Fly   388 FASRKTLRHHEYIHTGEKPYIC--DTCGQAFRQQTCLKNH-RKVH 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	20/85 (24%)
		C2H2 Zn finger	1198..1219	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1227..1255	CDD:275368	7/35 (20%)
		C2H2 Zn finger	1259..1280	CDD:275368	6/20 (30%)
		C2H2 Zn finger	1292..1313	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1322..1342	CDD:275368	6/19 (32%)
		zf-H2C2_2	1334..1361	CDD:290200	9/26 (35%)
		C2H2 Zn finger	1350..1373	CDD:275368	8/22 (36%)
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071	18/76 (24%)
		C2H2 Zn finger	158..179	CDD:275368	3/20 (15%)
		C2H2 Zn finger	188..209	CDD:275368	4/20 (20%)
		C2H2 Zn finger	218..239	CDD:275368	4/20 (20%)
		C2H2 Zn finger	254..275	CDD:275368	5/20 (25%)
		C2H2 Zn finger	294..315	CDD:275368	4/20 (20%)
		C2H2 Zn finger	325..345	CDD:275368	6/20 (30%)
		C2H2 Zn finger	352..373	CDD:275368	5/20 (25%)
		C2H2 Zn finger	381..401	CDD:275368	6/19 (32%)
		C2H2 Zn finger	409..429	CDD:275368	8/22 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100