DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43347 and CG11398

DIOPT Version :9

Sequence 1:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	330	Identity:	69/330 - (20%)
Similarity:	116/330 - (35%)	Gaps:	72/330 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1184 FHDPSMSLTIRKYHCKVCGEPVLGKDNIMKHAAEKHDGKGAYQCQFCSKFFLRLNYLEMHR---T 1245
            :.|..:||...:          |..:.:.:.:..:..|..::.|:.|...||....|..||   .
  Fly    19 YEDEELSLNTEE----------LQFEELNERSQHQQGGSPSFVCRRCPALFLTREELAAHRPTHR 73

  Fly  1246 YGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRM--HSDMAEVLRDFQCKLCSKLLGSRAALQRH 1308
            |........|...||.|||.|   ||..|.:..|  |:|    :|::.|..|......|:..:.|
  Fly    74 YQGGQQTPASEHACDACGRVF---QKHNALVDHMNAHND----VRNYPCPECPARFVQRSNRECH 131

  Fly  1309 SKEVHSRNSTVVSCPR--CQKLFQNRS-----------------------------NLKIHMLTH 1342
            .|.|| |...:.|||.  |:|.||.|.                             |.:.|:.:|
  Fly   132 LKNVH-RKVYLHSCPEPGCKKRFQQRRECDQHVKTVHQNERNLVCDTCSARFSHPVNYRKHLASH 195

  Fly  1343 SGVRPFKCAEPECNAAFTTKQCLQFHYKKVHNYTQEQMPKI-----ERSVAYTFDAYSGGMKVDF 1402
            ...:.:.|  |.|...|...:....|. .||:..:..:..:     .|.........:.|...|.
  Fly   196 GSAKSYGC--PICGKLFGRPENRDVHL-FVHSICKAYICSVCGADYMRRNQLIRHGLASGHHNDP 257

  Fly  1403 LGKQTATATPASAASAQAQPRPNAAVVSPSSFTEQAPRRRRKSLEDQSSMLSGSLQSDAEFSDDN 1467
            :.:|....:||.||..::|          .|..:::.....:.|:...::.|.....:::||:..
  Fly   258 IVRQKPQFSPALAAKNRSQ----------RSAIDESQDEELQWLKGVDALDSAGYLENSQFSNTG 312

  Fly  1468 LFEAI 1472
            ...||
  Fly   313 KMTAI 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	17/72 (24%)
		C2H2 Zn finger	1198..1219	CDD:275368	1/20 (5%)
		C2H2 Zn finger	1227..1255	CDD:275368	8/30 (27%)
		C2H2 Zn finger	1259..1280	CDD:275368	10/22 (45%)
		C2H2 Zn finger	1292..1313	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1322..1342	CDD:275368	9/50 (18%)
		zf-H2C2_2	1334..1361	CDD:290200	7/26 (27%)
		C2H2 Zn finger	1350..1373	CDD:275368	5/22 (23%)
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	7/19 (37%)
		C2H2 Zn finger	87..107	CDD:275368	10/22 (45%)
		C2H2 Zn finger	115..136	CDD:275368	5/20 (25%)
		C2H2 Zn finger	144..165	CDD:275368	7/20 (35%)
		C2H2 Zn finger	175..195	CDD:275368	2/19 (11%)
		C2H2 Zn finger	203..223	CDD:275368	5/22 (23%)
		C2H2 Zn finger	231..247	CDD:275368	1/15 (7%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100