DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43347 and zgc:173713

DIOPT Version :9

Sequence 1:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster
Sequence 2:	NP_001373793.1	Gene:	zgc:173713 / 100137115	ZFINID:	ZDB-GENE-080215-19	Length:	420	Species:	Danio rerio

Alignment Length:	239	Identity:	66/239 - (27%)
Similarity:	93/239 - (38%)	Gaps:	46/239 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1158 HT--EKTNCGGCNLKFEHPLYYRTHCSVFHDPSMSLTIRKYHCKVCGEPVLGKDNIMKHAAEKHD 1220
            ||  .|..|..|...|.|...:..|..: |...     :.:.||.||:....|.|:..| ...|.
Zfish   132 HTGERKFTCQECGKSFYHVGNFAAHMRI-HTGE-----KPFSCKQCGKSFCHKPNLDVH-MRVHT 189

  Fly  1221 GKGAYQCQFCSKFFLRLNYLEMHRTYGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRMHSDMAE 1285
            |:..|.|:.|.|.|.:......|........|    ..|..||:.:...:.|.||: |.|:..
Zfish   190 GEKPYTCEQCGKSFGQKQSFNTHMRIHTGKRP----CTCQQCGKSYYNARSLAAHM-RTHTGE-- 247

  Fly  1286 VLRDFQCKLCSKLLGSRAAL-----------------------QRHSKEVHSRNST---VVSCPR 1324
              |.|.|.||.|....:..|                       |:...::|.|..|   ..:|..
Zfish   248 --RPFSCILCRKSFSLKLTLIAHMRVHAREKPHTCEQCGKSFGQKQDLDIHMRIHTGEKPYTCTE 310

  Fly  1325 CQKLFQNRSNLKIHMLTHSGVRPFKCAEPECNAAFTTKQCLQFH 1368
            |.|.|.:.|:||.|:.||:|.:||.||  :|..:||||..|:.|
Zfish   311 CGKSFPHISSLKHHIRTHTGEKPFTCA--QCGKSFTTKTSLKNH 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	19/69 (28%)
		C2H2 Zn finger	1198..1219	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1227..1255	CDD:275368	6/27 (22%)
		C2H2 Zn finger	1259..1280	CDD:275368	7/20 (35%)
		C2H2 Zn finger	1292..1313	CDD:275368	6/43 (14%)
		C2H2 Zn finger	1322..1342	CDD:275368	8/19 (42%)
		zf-H2C2_2	1334..1361	CDD:290200	12/26 (46%)
		C2H2 Zn finger	1350..1373	CDD:275368	9/19 (47%)
zgc:173713	NP_001373793.1	COG5048	81..>406	CDD:227381	66/239 (28%)
		C2H2 Zn finger	84..104	CDD:275368
		C2H2 Zn finger	112..132	CDD:275368	66/239 (28%)
		C2H2 Zn finger	140..160	CDD:275368	5/20 (25%)
		C2H2 Zn finger	168..188	CDD:275368	7/20 (35%)
		C2H2 Zn finger	196..216	CDD:275368	5/19 (26%)
		C2H2 Zn finger	224..244	CDD:275368	7/20 (35%)
		C2H2 Zn finger	252..272	CDD:275368	5/19 (26%)
		C2H2 Zn finger	280..300	CDD:275368	3/19 (16%)
		C2H2 Zn finger	308..328	CDD:275368	8/19 (42%)
		C2H2 Zn finger	336..356	CDD:275368	9/19 (47%)
		C2H2 Zn finger	364..384	CDD:275368
		C2H2 Zn finger	392..412	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910