DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1628 and T10F2.2

DIOPT Version :9

Sequence 1:	NP_572639.2	Gene:	CG1628 / 31990	FlyBaseID:	FBgn0030218	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001380014.1	Gene:	T10F2.2 / 188387	WormBaseID:	WBGene00020422	Length:	301	Species:	Caenorhabditis elegans

Alignment Length:	306	Identity:	155/306 - (50%)
Similarity:	206/306 - (67%)	Gaps:	18/306 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 MHGGG-----TGNNI--NFVEGLIDFLAGSLGGAAQVYVSQPLDTVKVKLQTFPEAYRGMLDCFL 212
            ||..|     ||:..  :|.:|:||.|||:.||.|.||..|||||||||:||||..|...:.|..
Worm     1 MHESGEPTTATGDASANHFKDGIIDLLAGTAGGIANVYAGQPLDTVKVKVQTFPNLYSNWIVCLK 65

  Fly   213 STYRKDGVLRGLYAGSVPAVFANVAENSVLFAAYGGCQKFVAFCVGKETAGDLTTVQNACAGSLA 277
            .||:.||: ||||||::||:.||||||:|||.|||.|||.:|...|.|....:|.::||.:||||
Worm    66 DTYKLDGI-RGLYAGTLPALAANVAENAVLFTAYGYCQKTIATLNGLEDVRQMTPLENAFSGSLA 129

  Fly   278 ACFSTLTLCPTELIKCKLQALREMKNFVEPAHPQDIRTPWTLTRYIWRTEGIRGFYRGLSSTFLR 342
            |.|:...||||||:||||||.||||...         ||:::.|.|.:..|:|||:.|::.|..|
Worm   130 AVFAATVLCPTELVKCKLQAAREMKKKC---------TPFSVCRDIMKDTGVRGFFVGMTPTLAR 185

  Fly   343 EMPGYFFFFGSYEGTRELLRRDDQSKDDIGPLRTMIAGAIGGVCLWTSTFPADVIKSRIQVKNLN 407
            |:||||||||:||..|.||..:.|.|::||.::|.:||::||:.||||.:||||:|||:||....
Worm   186 EVPGYFFFFGAYETCRFLLTDEGQKKEEIGLVKTAMAGSVGGMALWTSIYPADVVKSRMQVTGGG 250

  Fly   408 ESMFAVGADIVRREGVLALYRGLLPSVLRTIPATATLFVVYEYTKR 453
            ..|..:|| :|:..|:..||:||||:.|||..|:..|||.||.|::
Worm   251 TFMSTLGA-VVKENGIRGLYKGLLPTNLRTCFASGCLFVAYEETRK 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1628	NP_572639.2	PTZ00169	162..455	CDD:240302	150/294 (51%)
		Mito_carr	170..252	CDD:278578	51/81 (63%)
		Mito_carr	263..364	CDD:278578	50/100 (50%)
		Mito_carr	369..455	CDD:278578	41/85 (48%)
T10F2.2	NP_001380014.1	Mito_carr	25..105	CDD:395101	51/80 (64%)
		Mito_carr	116..208	CDD:395101	50/100 (50%)
		Mito_carr	212..298	CDD:395101	41/85 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156776
Domainoid	1	1.000	106	1.000	Domainoid score	I4157
eggNOG	1	0.900	-	-		E1_KOG0763
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6957
Inparanoid	1	1.050	292	1.000	Inparanoid score	I1680
Isobase	1	0.950	-	0	Normalized mean entropy	S1473
OMA	1	1.010	-	-		QHG54095
OrthoDB	1	1.010	-	-		D1072378at2759
OrthoFinder	1	1.000	-	-		FOG0002272
OrthoInspector	1	1.000	-	-		oto19000
orthoMCL	1	0.900	-	-		OOG6_104887
Panther	1	1.100	-	-	LDO	PTHR45624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2214
SonicParanoid	1	1.000	-	-		X1947
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750