DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1628 and SLC25A52

DIOPT Version :10

Sequence 1:NP_572639.2 Gene:CG1628 / 31990 FlyBaseID:FBgn0030218 Length:459 Species:Drosophila melanogaster
Sequence 2:NP_001029344.4 Gene:SLC25A52 / 147407 HGNCID:23324 Length:297 Species:Homo sapiens


Alignment Length:312 Identity:66/312 - (21%)
Similarity:110/312 - (35%) Gaps:87/312 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 FLAGSLGGAAQVYVSQPLDTVKVKLQTFPEAYRGMLDCFLSTYRKDGVLRGLYAGSVPAVFANVA 237
            :|.|.......|.::.|:..|..:.|.:....|   |..|. .|:|| .|.||.|.:|.:.....
Human    34 YLCGCCAAFNNVAITYPIQKVLFRQQLYGIKTR---DAVLQ-LRRDG-FRNLYRGILPPLMQKTT 93

  Fly   238 ENSVLFAAYGGCQKFVAFCVGKE--TAGDLTT--VQNACAGSLAACFSTLTLCPTELIKCKLQAL 298
            ..:::|..|....     |:.::  .|.:..|  |....||:..|.|:     |.|.::..||..
Human    94 TLALMFGLYEDLS-----CLLRKHVRAPEFATHGVAAVLAGTAEAIFT-----PLERVQTLLQNH 148

  Fly   299 REMKNFVEPAHPQDIRTPWTLTRYIWRT---EGIRGFYRGLSSTFLREMPGYFFFFGSYEGTREL 360
            :....|             |.|...::.   .||..:||||.....|.......|||        
Human   149 KHHDKF-------------TNTYQAFKALKCHGIGEYYRGLVPILFRNGLSNVLFFG-------- 192

  Fly   361 LRRDDQSKDDIGPLR---------------TMIAGAIGGVCLWTSTFPADVIKSRIQVKNLNESM 410
            ||         ||::               ..|.|.:.|..|....||.:|:|:|:|.:      
Human   193 LR---------GPIKEHLPTATTHSAHLVNDFIGGGLLGAMLGFLCFPINVVKTRLQSQ------ 242

  Fly   411 FAVGAD------------IVRREGVLALYRGLLPSVLRTIPATATLFVVYEY 450
              :|.:            :.|...::.|:||...:..|::.:...:...||:
Human   243 --IGGEFQSFPKVFQKIWLERDRKLINLFRGAHLNYHRSLISWGIINATYEF 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1628NP_572639.2 Mito_carr 170..252 CDD:395101 19/78 (24%)
Mito_carr 263..364 CDD:395101 25/105 (24%)
Mito_carr 369..456 CDD:395101 20/109 (18%)
SLC25A52NP_001029344.4 Solcar 1. /evidence=ECO:0000255 28..108 19/83 (23%)
Mito_carr 31..112 CDD:395101 20/87 (23%)
Solcar 2. /evidence=ECO:0000255 116..200 27/118 (23%)
Mito_carr 118..203 CDD:395101 27/119 (23%)
Solcar 3. /evidence=ECO:0000255 209..296 18/92 (20%)
Mito_carr <229..297 CDD:395101 14/72 (19%)

Return to query results.
Submit another query.