DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA2 and CG34367

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_001097140.1 Gene:CG34367 / 5740879 FlyBaseID:FBgn0085396 Length:420 Species:Drosophila melanogaster


Alignment Length:373 Identity:88/373 - (23%)
Similarity:126/373 - (33%) Gaps:100/373 - (26%)


- Green bases have known domain annotations that are detailed below.


Human    11 FINSQPSLAECLTSFPPVADTFQSS------SIKTSTLSHSTLI----PPPFEQT---------I 56
            ||||       ::|....|||..|.      .|...::|.|..|    |.|.|::         .
  Fly    44 FINS-------ISSGGSYADTCASGEESVDIDITDLSVSESNTILAIDPEPTEESHSQREEHVET 101

Human    57 PSLNPGSHPRHGAGGRPKP-------------SPAGSRGSPVPAGAL----QPPEYPWMKEKKAA 104
            .||:|   ..|.|...|||             .|...:.|.:|..::    :....|     |.|
  Fly   102 YSLSP---TLHKAAVEPKPKNWLISEDLDVDSQPEDPKMSGLPTASITECTEDSNTP-----KLA 158

Human   105 KKTALLPAAAAAATAAATGPACLSHKESLEIADGS--GGGSRRLRTAYTNTQLLELEKEFHFNKY 167
            ....|||....:       |....::|..:..|.|  ....||.||.:|..||.|||:.|....|
  Fly   159 PDKPLLPEECVS-------PEPSRNREHCDPLDTSLVNTKQRRSRTNFTLDQLNELERLFEETHY 216

Human   168 LCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEG---------------KCK-- 215
            .....|.|::..|.|:|.:|:|||||||.|.::.    |||..:|               .|:  
  Fly   217 PDAFMREELSQRLGLSEARVQVWFQNRRAKCRKH----ENQMHKGFLVGSRSPPIATPLEPCRVA 277

Human   216 ------SLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPV 274
                  :|..|..........:...||..|||        |.....:....:|:.||.......:
  Fly   278 PYVSLAALRSSSVPSHPAAATSSNPQAPGVSG--------TSSSGKVVTVDSPHNHNPAISRSAI 334

Human   275 SPLTSNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEA--LEVP 320
            ...:|.......|....|.:   :|.......|.:.|.:..|  ..||
  Fly   335 KQFSSTVAAAAAFSAFDPAI---ISVAAHQYAAAITNGTVPAGLFSVP 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93 17/80 (21%)
Antp-type hexapeptide 94..99 1/4 (25%)
Homeodomain 144..200 CDD:459649 26/55 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 7/53 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279 3/21 (14%)
CG34367NP_001097140.1 Homeodomain 193..249 CDD:459649 26/55 (47%)
OAR 392..410 CDD:461067
Blue background indicates that the domain is not in the aligned region.

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