DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA2 and Abd-B

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_524896.2 Gene:Abd-B / 47763 FlyBaseID:FBgn0000015 Length:493 Species:Drosophila melanogaster


Alignment Length:231 Identity:69/231 - (29%)
Similarity:97/231 - (41%) Gaps:51/231 - (22%)


- Green bases have known domain annotations that are detailed below.


Human    27 PVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQ 91
            |..:|..|:::|..| :|.......|.|...|   |.:.|......|.|.      :..|.|...
  Fly   240 PGFETDTSAAVKRHT-AHWAYNDEGFNQHYGS---GYYDRKHMFAYPYPE------TQFPVGQYW 294

Human    92 PPEYPWMKEKKAAKKTALLPAA----AAAATAAATGPACLSHK---------------ESLEIAD 137
            .|.|...:...||...|.:..|    :|||..:..|.:..|::               |:...:.
  Fly   295 GPNYRPDQTTSAAAAAAYMNEAERHVSAAARQSVEGTSTSSYEPPTYSSPGGLRGYPSENYSSSG 359

Human   138 GSGGGS----------------------RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 180
            .|||.|                      |:.|..|:..|.|||||||.||.|:.:.:|.|:|..|
  Fly   360 ASGGLSVGAVGPCTPNPGLHEWTGQVSVRKKRKPYSKFQTLELEKEFLFNAYVSKQKRWELARNL 424

Human   181 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKS 216
            .|||||||:||||||||:|:.:|.:.||.:.....|
  Fly   425 QLTERQVKIWFQNRRMKNKKNSQRQANQQNNNNNSS 460

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93 10/50 (20%)
Antp-type hexapeptide 94..99 1/4 (25%)
Homeodomain 144..200 CDD:459649 33/55 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 5/19 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279
Abd-BNP_524896.2 Homeodomain 388..444 CDD:459649 33/55 (60%)
Blue background indicates that the domain is not in the aligned region.

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