DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXA2 and Dr

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_477324.1 Gene:Dr / 45285 FlyBaseID:FBgn0000492 Length:515 Species:Drosophila melanogaster


Alignment Length:182 Identity:56/182 - (30%)
Similarity:73/182 - (40%) Gaps:44/182 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    26 PPVADTFQSSSIKTSTLS--HSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAG 88
            ||.....||:.:..:.|:  |..:.|.||.    :|...:....|.||          |.|.|..
  Fly   334 PPPGSHMQSTILSPAALASGHVPIRPTPFS----ALAAAAVAWTGMGG----------GVPWPGT 384

Human    89 ALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACL-----SHKESLEIADGSGGGSRRLRT 148
            ...||..|          ..:.|.|.....  |..|..:     .||.           :|:.||
  Fly   385 RQMPPFGP----------PGMFPGAGFGGD--ANEPPRIKCNLRKHKP-----------NRKPRT 426

Human   149 AYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 200
            .:|..|||.|||:|...:||....|.|.::.|.|||.|||:||||||.|.||
  Fly   427 PFTTQQLLSLEKKFREKQYLSIAERAEFSSSLRLTETQVKIWFQNRRAKAKR 478

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93 12/52 (23%)
Antp-type hexapeptide 94..99 1/4 (25%)
Homeodomain 144..200 CDD:459649 29/55 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 2/3 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279
DrNP_477324.1 Homeodomain 422..478 CDD:459649 29/55 (53%)
Blue background indicates that the domain is not in the aligned region.

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