Protein Alignment HOXA2 and bap

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 68/247 - (27%)
• Similarity: 88/247 - (35%)
• Gaps: 66/247 - (26%)

Human    42 LSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKP---SPAGSR-----GSP-------------- 84
            ||.|...|......:...||.:.........|:|   .|:..|     .||
  Fly    16 LSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQ 80

Human    85 ---VPAGALQPPEY-----------------PWMKEKKAA----KKTALLPAAAAA--------- 116
               :...|.||..|                 .......||    :|.|...:..||
  Fly    81 PKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTS 145

Human   117 --ATAAATGPACLSHKESLEIADGSG-GGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAA 178
              :...:..|...|..||....|||| ...:|.|.|:::.|:.|||:.|...:||..|.|.|:|.
  Fly   146 NDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAK 210

Human   179 LLDLTERQVKVWFQNRRMKHKRQTQCKENQNSE----GKCKSLEDSEKVEED 226
            .|.|||.|||:||||||.|.||    |:.|..|    |..|.:.....|.||
  Fly   211 SLRLTETQVKIWFQNRRYKTKR----KQIQQHEAALLGASKRVPVQVLVRED 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		14/75 (19%)
		Antp-type hexapeptide	94..99		1/21 (5%)
		Homeodomain	144..200	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		10/33 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279
bap	NP_732637.1	Homeodomain	176..232	CDD:459649	28/55 (51%)