Protein Alignment HOXA2 and tin

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_524433.1
• Gene: tin / 42536
• FlyBaseID: FBgn0004110
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 62/271 - (22%)
• Similarity: 93/271 - (34%)
• Gaps: 99/271 - (36%)

Human    39 TSTLSHSTLIPPP----------------------------FEQTIPSLN--------------- 60
            |::.|.|.|:|||                            |:.:..:.|
  Fly   109 TTSSSLSPLLPPPPHQLYGGYQDYGMPAHMFQHHHGHPHQSFQHSASAYNMSASQFYAGASATAY 173

Human    61 --PGSHPRHGAG-----GRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAA---------KKTAL 109
              |.::..:.||     |...||..|.:...:|...:.|.  |.:....:|         :|..:
  Fly   174 QTPATYNYNYAGSGEVYGGATPSAVGIKSEYIPTPYVTPS--PTLDLNSSAEVDSLQAPTQKLCV 236

Human   110 LPAAAAAATAAATGPACLS---------HKESLEIAD----------------GSGGGS------ 143
            .|.:......|:...:..|         .|::.::..                ||..||
  Fly   237 NPLSQRLMETASNSSSLRSIYGSDEGAKKKDNSQVTSSRSELRKNSISGNSNPGSNSGSTKPRMK 301

Human   144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR-QTQCKEN 207
            |:.|..::..|:||||..|...|||....|..||..|:|:..|||:||||||.|.|| ...|
  Fly   302 RKPRVLFSQAQVLELECRFRLKKYLTGAEREIIAQKLNLSATQVKIWFQNRRYKSKRGDIDC--- 363

Human   208 QNSEGKCKSLE 218
               ||..|.|:
  Fly   364 ---EGIAKHLK 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		16/100 (16%)
		Antp-type hexapeptide	94..99		1/4 (25%)
		Homeodomain	144..200	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		7/22 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279
tin	NP_524433.1	Homeodomain	302..358	CDD:459649	26/55 (47%)