Protein Alignment HOXA2 and NK7.1

DIOPT Version :10

• Sequence 1: NP_006726.1
• Gene: HOXA2 / 3199
• HGNCID: 5103
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_650357.2
• Gene: NK7.1 / 41747
• FlyBaseID: FBgn0024321
• Length: 721
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 80/305 - (26%)
• Similarity: 117/305 - (38%)
• Gaps: 71/305 - (23%)

Human    27 PVADTFQSSSI-KTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGAL 90
            |:..|.||..: |::|...|:..|...::.:.|.         ....|..||.||..|
  Fly   298 PMPATKQSQILGKSATKKESSGKPAAKKKKLSST---------VALPPDISPTGSSDS------- 346

Human    91 QPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGS------RRLRTA 149
                  .|::|..|..:: .|.:...|...:...:.|...|     |.|..||      ::.||.
  Fly   347 ------LMRDKLMANNSS-SPGSNVNAQMQSNANSTLETTE-----DDSDSGSTDARRKKKARTT 399

Human   150 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKC 214
            :|..|:.||||.|...|||....|.|:|.||.:||.|||:||||||.|.|:|.....|:.:|.|.
  Fly   400 FTGRQIFELEKMFENKKYLSASERTEMAKLLMVTETQVKIWFQNRRTKWKKQDNVTNNEAAEHKS 464

Human   215 KSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSF-PVSPLT 278
            .:                            .:.|.|.     :....|:|...|.:|. ..||..
  Fly   465 SN----------------------------AKPGATG-----TATTTPSGEPTDKRSSNATSPTV 496

Human   279 SNEKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDSPEALEVPSLQ 323
            .|...:...: :||..||..|....|.....|.::.|. :||:.|
  Fly   497 GNAATIAEIK-KSPKSPNRGSNNNNNNTLNNNVNNSEG-KVPAKQ 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXA2	NP_006726.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..93		9/50 (18%)
		Antp-type hexapeptide	94..99		0/4 (0%)
		Homeodomain	144..200	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..229		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..279		6/22 (27%)
NK7.1	NP_650357.2	Homeodomain	394..450	CDD:459649	29/55 (53%)