DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment HOXA2 and zen

DIOPT Version :10

Sequence 1:NP_006726.1 Gene:HOXA2 / 3199 HGNCID:5103 Length:376 Species:Homo sapiens
Sequence 2:NP_476793.1 Gene:zen / 40828 FlyBaseID:FBgn0004053 Length:353 Species:Drosophila melanogaster


Alignment Length:181 Identity:62/181 - (34%)
Similarity:84/181 - (46%) Gaps:20/181 - (11%)


- Green bases have known domain annotations that are detailed below.


Human   144 RRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQ 208
            :|.|||:|:.||:|||.||..|.||.|.||:|||..|.|.|||||:||||||||.|:..|.....
  Fly    91 KRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREP 155

Human   209 NSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGD---SQ 270
            .|..|.     ::...|....:.:.::.:|.|..  .|||....:.......||.....|   ||
  Fly   156 KSNAKL-----AQPQAEQSAHRGIVKRLMSYSQD--PREGTAAAEKRPMMAVAPVNPKPDYQASQ 213

Human   271 SFPVSPLTSN--------EKNLKHFQHQSPTVPNCLSTMGQNCGAGLNNDS 313
            .......|:|        .:.|:|.. |:...|. :||...:.|...|:.|
  Fly   214 KMKTEASTNNGMCSSADLSEILEHLA-QTTAAPQ-VSTATSSTGTSTNSAS 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXA2NP_006726.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 42..93
Antp-type hexapeptide 94..99
Homeodomain 144..200 CDD:459649 36/55 (65%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..229 5/30 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 257..279 5/24 (21%)
zenNP_476793.1 Homeodomain 91..147 CDD:459649 36/55 (65%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.